Zhixian Gao

Two neuroanatomical subtypes of major depressive disorder exhibit dissociable clinical profiles and distinct molecular signatures

Chang Wang, C H I Zhang, Zidan Li, Chen Liu et autres

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Multiscale Comparative Analyses of OVB-Organoids and Cerebral Organoids

Jingyi Yang, Xi Zhang, Shuang Li, Zhixian Gao

Organoid technology is critical for studying human brain development, but existing single-organoid culture systems fail to simulate inter-organ interactions (e.g., optic vesicle-brain) in embryogenesis. This study aimed to establish a more comprehensive in vitro model for early neurodevelopment. We established standardized protocols …

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Biosynthesis of ZnONPs and TTOL for enhancing preservation of CTS films

Jiaqi Lin, Jiaxin Zhang, Yujing Ma, Han Cui et autres

• Chitosan-ZnO nanoparticles-tea tree oil liposomes composite films were prepared. • ZnO nanoparticles and tea tree oil liposomes addition enhanced the mechanical of chitosan films. • The composite films showed good antibacterial activities. • The composite films have great potential for fruit …

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Corrigendum to “Integrated Multi-channel Microfluidic Biosensing Chip Based on Chain Amplified Enhanced Fluorescence for Determination of SEs” [Sens. Actuator B. Chem., Volume 442, 1 November 2025, 138149]

Meiling Wang, Wei Pang, Jiaxin Zhang, Li Wang et autres

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Exploring potential resting-state EEG biomarkers of obsessive-compulsive disorder based on explainable machine learning analysis of independent training and test samples

Zongya Zhao, Junming Wang, Yanxiang Niu, Mengyue Qiu et autres

BACKGROUND: At present, the clinical diagnosis of obsessive-compulsive disorder (OCD) is primarily based on interviews with patients by experienced psychiatrists, which is inherently limited by its subjectivity. Therefore, there is a pressing clinical need to identify objective biomarkers of OCD. Although the …

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Dual functional G-quadruplex/β-cyclodextrin@AuNP/antibody probes for fluorescence assay of atrazine

Hui Huang, Jiang Wang, Zhixian Gao, Shiping Yang

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Applications of DNA origami in biomedicine: advances, challenges, and prospects

Ruipeng Chen, Xuexia Jia, Wei Pang, Yingao Yang et autres

DNA serves as a fundamental carrier of genetic information, and its unique properties allow it to be used as a versatile structural component for the engineering and self-assembly of nanostructures. The advent of DNA templates has significantly improved self-assembled DNA nanostructures, and …

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Melanin‐derived Biomimetic Nanoparticles Improve Patency and Tissue Regeneration of Vascular Grafts via ROS Scavenging and Immunomodulation in an Atherosclerotic Rat Model

Kang Qin, Wengeng Guo, Yu Zhang, Haoxuan Sun et autres

Abstract Surgically bypassing or replacing using biodegradable synthetic small diameter vascular grafts (SDVGs) have garnered significant attention. However, complications such as thrombosis and foreign polymer‐induced local inflammation severely impair graft patency in vivo. To address these challenges, a biomimetic nanoparticle is developed, …

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Highly sensitive, self-powered and ultra-stretchable amphibious ionogel artificial skin

Mengmeng Chen, Jiangshan Zhang, Jiahong Yang, Yuan Yang Peng et autres

Abstract Ionogel, a novel flexible electronic material, presents a plethora of applications. Despite its potential, the fabrication of multifunctional ionogel with high-performance suitable for diverse scenarios remains a significant challenge. In this study, we prepare a multifunctional amphibious ionogel skin (AIGS) using …

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A 3D-printed, self-driven microfluidic sensor chip for point-of-care testing (POCT) of norovirus

Weiya Wang, Jiadi Sun, Tao Wang, Jin Wu et autres

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A novel efficient pretreatment device integrated with chitosan aerogel and hydrogel composite membrane for detection of norovirus in seafood

Ran Li, Rui Zhang, Ruixiang Shi, Ting Hu et autres

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Label-Free SERS Platform Assisted by Machine Learning for Multi-Target Detection and Physiological State Classification in Sweat

Banglei Zhu, Jin Chen, Bingwei Wang, Huanying Zhou et autres

The detection of sweat metabolites is crucial for health monitoring, disease screening, and personalized medicine. Traditional methods encounter challenges like low metabolite concentrations, complex biological matrices, and difficulty in achieving multitarget simultaneous detection, limiting sensitivity, stability, and multiplexing capabilities. This study introduces …

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