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Jianhua Yin, Yuhui Zheng, Zhuoli Huang, Wenwen Zhou et autres
Human peripheral blood exhibits molecular and cellular heterogeneity across populations, yet the underlying mechanisms remain unclear. We present the Chinese Immune Multi-Omics Atlas (CIMA), characterizing molecular variations linked to sex, age, and genetic variants through multi-omics analysis of more than 10 million …
cn, hk, sg (code pays fourni par la source)
Lianxin Zhang, Guolin Miao, Si Mei, Yufei Han et autres
Sepsis-induced cardiac dysfunction (SICD) is a major contributor to mortality in sepsis. Kinesin family member 13B (KIF13B) has been identified as a critical protective factor for metabolic disorder and cardiovascular disease; however, the role of KIF13B in SICD remains unknown. After introducing …
cn, us (code pays fourni par la source)
Yong Bai, Xiangyu Guo, Keyin Liu, Bingjie Zheng et autres
Spatially resolved transcriptomics (SRT) for characterizing spatial cellular heterogeneities in tissue environments requires systematic analytical approaches to elucidate gene expression variations within their physiological context. Here, we introduce SpaSEG, an unsupervised deep learning model utilizing convolutional neural networks for multiple SRT analysis …
cn, dk (code pays fourni par la source)
W H Zhang, Li Jia Deng, Fan Yang, Jianhong Liu et autres
INTRODUCTION: Hysterectomy is the most common surgical procedure in the field of gynaecology. The traditional multiport laparoscopy, transumbilical laparoendoscopic single-site surgery (TU-LESS) and transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy approaches have been implemented to varying degrees in clinical practice. At …
cn (code pays fourni par la source)
X S Zhang, Bin Liu, Xin Du, Y L Zhang et autres
Patients receiving initial flumatinib therapy had higher cumulative incidences of therapy responses and higher probability of FFS than those receiving initial imatinib therapy, whereas the incidence of severe hematologic adverse events was comparable between the two cohorts.
cn, hk, us (code pays fourni par la source)
M Y Zhang, Min Bao, Dayu Shi, H X Shi et autres
Compared with middle-aged and elderly patients, young patients with MPN had unique clinical and genetic characteristics.
cn (code pays fourni par la source)
Min Bao, Dayu Shi, H X Shi, Xi Liu et autres
HRQoL in patients with MPN was significantly reduced, especially in patients with MF. Sociodemographic and clinical variables were significantly associated with the HRQoL in patients with MPNs.
cn (code pays fourni par la source)
Yuye Chen, J B Liu, C H Zhong, Yixiong Xiao et autres
OBJECTIVE: To establish an indicator system for assessment of schistosomiasis transmission risk after transmission interruption in Hubei Province, so as to provide insights into the precise control of schistosomiasis. METHODS: The indicator system was preliminarily established based on data collection, literature review, …
cn (code pays fourni par la source)
W Y Liu, Lifu Zhang, Heng Yi Xu, Shaoyan Xu et autres
0.023-0.065) L/s on the day before the test, respectively. The results indicate that air pollution have short-term and lag effects on lung function of school-age children in Hangzhou.
cn (code pays fourni par la source)
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