Rafaela Ceron

[Dataset] Increased Osteocyte Lacunae Size and Organic Matrix Pyridinoline Content in Transiliac Bone from Patients with Axial Spondyloarthritis (axSpA)

Barbara M. Misof, Natalia P. Machado, Shibarjun Mandal, Markus A. Hartmann et autres

Increased Osteocyte Lacunae Size and Organic Matrix Pyridinoline Content in Transiliac Bone from Patients with Axial Spondyloarthritis (axSpA)

Barbara M. Misof, Natália Pereira Machado, Shibarjun Mandal, Markus A. Hartmann et autres

Axial spondyloarthritis (axSpA) is a chronic inflammation disorder commonly associated with osteoporosis and fractures. For further information about the pathophysiology of the latter, we analyzed transiliac biopsy samples from n = 21 men with axSpA (age 46 ± 6 years, mean ± …

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Effect of an oral antidiabetic, sitagliptin, a DPP-4 inhibitor, on bone remodeling: study in ovariectomized rats

Luciana Muniz Pechmann, Vicente Florentino Castaldo Andrade, Thais Andrade Costa Casagrande, Rafaela Ceron et autres

Objective: To evaluate the effects of sitagliptin, a DPP-4 inhibitor, on bone remodeling using dynamic histomorphometry and assess DPP4 gene expression in bone tissue of ovariectomized (OVX) rats, a model of hypoestrogenism. Method: Non-diabetic female Wistar rats were divided into five groups: …

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Efeitos protetores da melatonina no osso em ratas ovariectomizadas: insights a partir da histomorfometria

Fatima Sandmann Afonso, Rafaela Ceron, Angela Maria Reck, Letícia Capote Santos et autres

Objetivo: Avaliar os efeitos da melatonina sobre parâmetros estruturais e de remodelação nas tíbias de ratas fêmeas Wistar ovariectomizadas (OVX) e submetidas à cirurgia SHAM. Métodos: Sessenta ratas Wistar foram submetidas à cirurgia de OVX (n=30) ou cirurgia SHAM (n=30) com 20 …

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Low Bone Turnover, Mineralization Impairment, and Cortical Alterations in Patients with Axial Spondyloarthritis: A Histomorphometric Study

Natália Pereira Machado, Marcelo M. Pinheiro, Domingos Candiota Chula, Rafaela Ceron et autres

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Hepatic and osteogenic effects of dulaglutide and semaglutide in an acute model of hepatotoxicity in mice

Bruna Christ Faria, Kauê Marcel de Oliveira, Débora Rasec Radulski, Maria Carolina Stipp et autres

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Melatonin and the benefits of its supplementation during peri-menopause and menopause

Angela Maria Reck-Aguiar, Rafaela Ceron, Fátima Corrêa Sandmann Afonso, Carolina Aguiar Moreira et autres

Melatonin is a hormone produced by the pineal gland, and its main role is to regulate the circadian cycle.However, the function of melatonin goes further, playing a significant role in relation to psychomotor changes, sleep disorders and a positive influence on well-being.Due …

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BURDEN OF LOW BONE TURNOVER, MINERALIZATION DEFECT AND CORTICAL ALTERATIONS IN PATIENTS WITH ANKYLOSING SPONDYLITIS: A HISTOMORPHOMETRIC STUDY

Natália Pereira Machado, Marcelo Antônio Amaro Pinheiro, Domingos Candiota Chula, Rafaela Ceron et autres

BACKGROUNDAnkylosing spondylitis (AS) is an immune-mediated inflammatory disease associated with an increased risk of fractures, and the pathophysiology of bone fragility in these patients is poorly understood.This study aimed to analyze the histomorphometric and densitometric parameters of male, young (< 55 years) …

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