Yuanyuan Gong

The unseen danger: cumulative laser-induced maculopathy from indirect exposure during cat play

Haoliang Zhang, Tong Li, Yuanyuan Gong

cn (code pays fourni par la source)

Intravitreal Gene Therapy with LX102-C01 in Neovascular Age-Related Macular Degeneration: A Phase I Dose-Escalation Study of 12-Month Safety and Efficacy Outcomes

Junran Sun, Mengxi Shen, Jieqiong Chen, Yidong Wu et autres

Purpose To assess the safety, tolerability, and preliminary efficacy of a single intravitreal injection of LX102-C01 in eyes with neovascular age-related macular degeneration (nAMD) followed up to 52 weeks. Design Open-label, single-center, dose-escalation investigator-initiated trial (IIT; NCT05831007) with two cohorts (3E10 vg …

cn, us (code pays fourni par la source)

Air pollution exposure and prevalence of non-alcoholic fatty liver disease and related cirrhosis: A systematic review and meta-analysis

Xingyi He, Shipeng Zhang, Qinglin Bai, Moshen Pan et autres

A systematic review and meta-analysis were used to investigate the relationship between air pollution exposure and the prevalence of non-alcoholic fatty liver disease (NAFLD) and its related cirrhosis. Through this study, we hope to clarify the potential public health risks of air …

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Spectrum of retinal microvascular ischemia in patients with COVID-19 based on multimodal imaging

Min Zhang, Junran Sun, Chanchan Wang, Li Su et autres

Purpose: To describe and evaluate the multimodal imaging findings in retinal microvascular ischemia associated with COVID-19 infection. Methods: was defined as the presence of isolated or multiple focal retinal whitening(s) on color fundus images. Patients with retinal vessel occlusion or retinopathies secondary …

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Double-dose investigation of aflibercept in neovascular age-related macular degeneration (DIANA): a real-world study

Min Zhang, Xing Liu, Yuanyuan Gong, Tianwei Qian et autres

BACKGROUND: To investigate the clinical effects of double-dose (4 mg) aflibercept treatment in neovascular age-related macular degeneration (nAMD), compared with the standard-dose (2 mg) treatment. METHODS: A total of 108 eyes from 97 patients with nAMD and received intravitreal aflibercept 2 mg …

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Cloudy Vitelliform Submaculopathy as an Early Sign of Primary Vitreoretinal Lymphoma

Chong Chen, Kun Liu, Yuanyuan Gong, Suqin Yu et autres

Chen, Chong MD; Liu, Kun MD, PhD; Gong, Yuanyuan MD; Yu, Suqin MD; Xu, Xun MD; Su, Li MD, PhDEditor(s): Grewal, Dilraj; Valikodath, Nita; Justin, Grant A. Author Information

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GENETIC FACTORS AND CHARACTERISTICS ON SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY ARE ASSOCIATED WITH CHOROIDAL THICKNESS IN ABCA4-RELATED RETINOPATHY

Yimin Wang, Jieqiong Chen, Min Zhang, Suqin Yu et autres

PURPOSE: To investigate the possible correlation factors of choroidal thickness in ABCA4 -related retinopathy. METHODS: A total of 66 patients were included in the cohort. It is a retrospective, cross-sectional laboratory investigation. The patients were tested using whole-exon sequencing and ophthalmic examinations, …

cn, Zambie, us (code pays fourni par la source)

Diagnostic Challenges in PD-1 Inhibitor Induced Panuveitis in a Teenage Girl with Chest Soft Tissue Sarcoma - A Case Report

Yinchen Shen, Yuanyuan Gong, Li Su

PURPOSE: To report a case of programmed cell death receptor-1 (PD-1) inhibitor induced panuveitis. METHOD: Observational case report of a 13-year-old Chinese girl presented as panuveitis. The clinical course, imaging performance, laboratory examination, differential diagnosis, treatment and prognosis were described. RESULT: Patient …

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Appearance of retinal arterial macroaneurysms in patients using swept-source optical coherence tomographic angiography

Yi Song, Weican Zhang, Suqin Yu, Yuanyuan Gong

BACKGROUND: Retinal arterial macroaneurysm (RAM) is a common clinical disease leading to vision loss in elderly individuals. The appropriate interpretation of swept-source optical coherence tomographic angiography (SS-OCTA), a noninvasive examination, is easy and convenient for detecting the status of RAMs and guiding …

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Gastric cancer cell-derived extracellular vesicles disrupt endothelial integrity and promote metastasis

Min Wang, Wei Cai, Aijun Yang, Chenyu Wang et autres

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Efficacy of Initial vs. Delayed Photodynamic Therapy in Combination With Conbercept for Polypoidal Choroidal Vasculopathy

Zuhua Sun, Yuanyuan Gong, Yating Yang, Ying Huang et autres

Purpose To compare the efficacy of initial vs. delayed photodynamic therapy (PDT) in combination with intravitreal injection of conbercept (IVC) for polypoidal choroidal vasculopathy (PCV). Design Multicenter, randomized, non-inferiority clinical trial. Subjects Naïve PCV patients. Methods Patients were randomized 1:1 into two …

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Resolution of Foveal Lipid Deposition in Adult-Onset Coats Disease With Combined Focal Laser Photocoagulation and Anti-VEGF Therapy

Xiaoyu Xu, Juliet O. Essilfie, Yuanyuan Gong, Su-Quin Yu et autres

A major cause of poor visual prognosis in Coats disease is the formation of fibrovascular changes following dense foveal lipid deposition. The authors document the multimodal imaging findings of a 38-year-old woman and a 23-year-old man with adult-onset Coats disease who presented …