KENNETH J. RUSSELL

ARTIA-Cervix: A Prospective Clinical Trial to Assess Patient Reported Intestinal Toxicity with Adaptive External Beam Radiation Therapy in the Treatment of Cervical Cancer

Jyoti Mayadev, K.V. Albuquerque, Samuel Marcrom, S.G. Kohlmyer et autres

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Daily Adaptive vs. Non-Adaptive External Beam Radiation Therapy with Concurrent Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer (NSCLC): A Prospective Randomized Trial of an Individualized Approach for Toxicity Reduction (ARTIA-Lung)

Dennis N. Stanley, Joseph M. Harms, Adam J. Kole, Michael Christian Dobelbower et autres

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ARTIA-Cervix: A prospective clinical trial to assess patient reported intestinal toxicity with adaptive external beam radiation therapy in the treatment of cervical cancer (1277)

Jyoti Mayadev, Kevin Albuquerque, Samuel Marcrom, S.G. Kohlmyer et autres

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Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases

Anthony E. Mascia, Emily C. Daugherty, Yongbin Zhang, Eunsin Lee et autres

Importance: To our knowledge, there have been no clinical trials of ultra-high-dose-rate radiotherapy delivered at more than 40 Gy/sec, known as FLASH therapy, nor first-in-human use of proton FLASH. Objectives: To assess the clinical workflow feasibility and treatment-related toxic effects of FLASH …

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FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study

Emily C. Daugherty, Anthony E. Mascia, Yong Zhang, Eunsin Lee et autres

BACKGROUND: In preclinical studies, FLASH therapy, in which radiation delivered at ultrahigh dose rates of ≥40 Gy per second, has been shown to cause less injury to normal tissues than radiotherapy delivered at conventional dose rates. This paper describes the protocol for …

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A Comparison of Radical Radiotherapy Techniques in the Treatment of the Para-aortic Strip in Stage 2 Testicular Seminoma Patients

Andrew W. Duncan, Graham J. Macdonald, KENNETH J. RUSSELL, Andrew Bromiley

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A Prospective Study of a Resorbable Intravesical Fiducial Marker for Bladder Cancer Radiation Therapy

Matthew D. Greer, Stephanie K. Schaub, Stephen R. Bowen, Jay Justin Liao et autres

Purpose We conducted a prospective pilot study to evaluate safety and feasibility of TraceIT, a resorbable radiopaque hydrogel, to improve image guidance for bladder cancer radiation therapy (RT). Methods and Materials Patients with muscle invasive bladder cancer receiving definitive RT were eligible. …

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Patterns and Predictors of First-Line Taxane Use in Patients with Metastatic Triple-Negative Breast Cancer in US Clinical Practice

Joyce O’Shaughnessy, Leisha A. Emens, Jane Yuet Ching Hui, Wei Wang et autres

We investigated first-line (1L) treatment patterns and predictors of taxane use to better understand the evolving metastatic triple-negative breast cancer (mTNBC) treatment landscape. This retrospective analysis of the Truven Health MarketScan® (Somers, NY, USA) Database included women with mTNBC who received 1L …

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Use of 18F-fluciclovine PET/CT (FluPET) for prostate cancer (PC): Initial results from a prospective registry at a tertiary academic center.

Risa Liang Wong, Heather H. Cheng, Sarah K. Holt, Nathan Conrad et autres

29 Background: FluPET, a next-generation imaging modality approved in 2016 for suspected PC recurrence with elevated PSA after prior therapy, is becoming more widely available; however, practice patterns and impact on outcomes is unknown. We hypothesize FluPET is ordered for a variety …

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TraceIT: A prospective pilot study of a temporary intravesical fiducial marker for bladder cancer radiation therapy.

Matthew D. Greer, Stephanie K. Schaub, Stephen R. Bowen, Jay Justin Liao et autres

457 Background: Precision image-guided radiotherapy (RT) for patients (pts) with muscle-invasive bladder cancer (MIBC) is limited by daily anatomic variation and difficulty visualizing the tumor bed. We hypothesized that TraceIT, a radiopaque resorbable hydrogel, can be injected around the tumor bed to …

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High‐grade serous peritoneal cancer follows a high stromal response signature and shows worse outcome than ovarian cancer

Francis Jacob, Rosa Lina Marchetti, André B. Kind, KENNETH J. RUSSELL et autres

In the era of personalized medicine, where transition from organ-based to individualized genetic diagnosis takes place, the tailoring of treatment in cancer becomes increasingly important. This is particularly true for high-grade, advanced FIGO stage serous adenocarcinomas of the ovary (OC), fallopian tube …

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195P Neoadjuvant chemotherapy (NACT) use and response in US patients with early-stage triple-negative breast cancer in the National Cancer Database (NCDB)

Mehr Kashyap, Mary Kathryn Downer, Márcio Debiasi, KENNETH J. RUSSELL et autres

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