Mengmeng Yuan

m6A-RegBase enables regulatory investigation of m6A RNA modification in plants

Beilei Lei, Pengjun Ding, Minggui Song, Yuhang Ma et autres

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Bibliometric Analysis of Physical Education Research in China from 2014 to 2024

Hao Zeng, Youbing Zhao, Yingying Tao, Mengmeng Yuan et autres

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Strong associations between fasting lipids and glucose concentrations and ALT levels strengthened with increasing ALT quantiles

Wei Liu, Lipu Shi, Mengmeng Yuan, Yonghui Zhang et autres

BACKGROUND: A persistent redox state and excessive reactive species involved in carbohydrate and lipid metabolism lead to oxidative damage in the liver, however, how fasting plasma concentrations of lipids and glucose are associated with fasting blood levels of alanine transaminase (ALT) and …

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SLC35D3 promotes white adipose tissue browning to ameliorate obesity by NOTCH signaling

Hongrui Wang, Liang Yu, Jine Wang, Yaqing Zhang et autres

White adipose tissue browning can promote lipid burning to increase energy expenditure and improve adiposity. Here, we show that Slc35d3 expression is significantly lower in adipose tissues of obese mice. While adipocyte-specific Slc35d3 knockin is protected against diet-induced obesity, adipocyte-specific Slc35d3 knockout …

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ZFYVE28 mediates insulin resistance by promoting phosphorylated insulin receptor degradation via increasing late endosomes production

Liang Yu, Mengchen Xu, Yupeng Yan, Shuchen Huang et autres

Insulin resistance is associated with many pathological conditions, and an in-depth understanding of the mechanisms involved is necessary to improve insulin sensitivity. Here, we show that ZFYVE28 expression is decreased in insulin-sensitive obese individuals but increased in insulin-resistant individuals. Insulin signaling inhibits …

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Changes in m6A RNA methylation are associated with male sterility in wolfberry

Jiawen Zhao, Chujun Zhang, Sifan Li, Mengmeng Yuan et autres

Abstract Background N 6 -methyladenosine (m 6 A) modification is the most abundant type of RNA modification in eukaryotic cells, playing pivotal roles in multiple plant growth and development processes. Yet the potential role of m 6 A in conferring the trait …

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Correction: A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension

Xiao Xiao, Rui Li, Cunjin Wu, Yupeng Yan et autres

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A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension

Xiao Xiao, Rui Li, Cunjin Wu, Yupeng Yan et autres

BACKGROUND: Compared with patients who require fewer antihypertensive agents, those with apparent treatment-resistant hypertension (aTRH) are at increased risk for cardiovascular and all-cause mortality, independent of blood pressure control. However, the etiopathogenesis of aTRH is still poorly elucidated. METHODS: We performed a …

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Novel FBN1 mutations are responsible for cardiovascular manifestations of Marfan syndrome

Jine Wang, Yupeng Yan, Jinxing Chen, Ling Gong et autres

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