Samuel L. Malnik

Surgical treatment of brainstem cavernous malformations in pregnancy: a retrospective single-center series and systematic review of the literature

Elsa Nico, Olga Ciobanu-Caraus, Ashia M. Hackett, Anant Naik et autres

OBJECTIVE: Brainstem cavernous malformations (BSCMs) are rare neurovascular lesions, and they are especially rare during pregnancy. Pregnancy was not considered in the international consensus on patient-related factors that influence surgical treatment decisions for BSCMs. Therefore, the authors sought to analyze the association …

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Picket fence technique for clip reconstruction of complex intracranial aneurysms

Sirin Gandhi, Joelle N. Hartke, Samuel L. Malnik, Charuta G. Furey et autres

OBJECTIVE: Complex intracranial aneurysms characterized by wide necks, calcifications, intraluminal thrombus formation, irregular dome morphology, and involvement of critical branch vessels pose a formidable challenge for neurosurgeons. The "picket fence" clipping technique is an advanced clip reconstruction strategy for complex intracranial aneurysms. …

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Posterior Inferior Cerebellar Artery Double Reimplantation Bypass for Treatment of a Dolichoectatic Posterior Inferior Cerebellar Artery Aneurysm: A Technical Report

Ashia M. Hackett, Christopher Adereti, Elsa Nico, Lea Scherschinski et autres

BACKGROUND AND IMPORTANCE: The surgical management of posterior inferior cerebellar artery (PICA) aneurysms often poses a challenge because of tight surgical corridors, proximity to the lower cranial nerves, and the presence of perforators supplying the medulla. This report describes an excision and …

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Analysis of the impact of a rhinologist-assisted endoscopic approach on a single neurosurgeon’s outcomes in transsphenoidal resection of pituitary adenomas

Arvind Mohan, Clare Grady, Samuel L. Malnik, Anil Patel et autres

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Leveraging machine learning to develop a postoperative predictive model for postoperative urinary retention following lumbar spine surgery

Samuel L. Malnik, Ken Porche, Yusuf Mehkri, Sijia Yue et autres

Introduction: Postoperative urinary retention (POUR) is the inability to urinate after a surgical procedure despite having a full bladder. It is a common complication following lumbar spine surgery which has been extensively linked to increased patient morbidity and hospital costs. This study …

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Assessing the Relationship between Surgical Timing and Postoperative Seizure Outcomes in Cavernoma-Related Epilepsy: A Single-Institution Retrospective Analysis of 63 Patients with a Review of the Literature

Elsa Nico, Christopher Adereti, Ashia M. Hackett, Andrea Bianconi et autres

Background: Patients with supratentorial cavernous malformations (SCMs) commonly present with seizures. First-line treatments for cavernoma-related epilepsy (CRE) include conservative management (antiepileptic drugs (AEDs)) and surgery. We compared seizure outcomes of CRE patients after early (≤6 months) vs. delayed (>6 months) surgery. Methods: …

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Inversed probability case-control analysis of operative burr hole evacuation versus subdural evacuating port system for chronic subdural hematomas: Clinical and economic outcomes

Arvind Mohan, Samuel L. Malnik, Clare Grady, Brandon Lucke‐Wold et autres

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Spinal cord injury and neurogenic lower urinary tract dysfunction: what do we know and where are we going?

William Dodd, Kartik Motwani, Coulter Small, Kevin Pierre et autres

One of the well reported but difficult to manage symptoms of spinal cord injury (SCI) is neurogenic lower urinary tract dysfunction (NLUTD). The type of NLUTD is variable based on location and extent of injury. SCI affects more males and NLUTD is …

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Halo vest immobilization – an institutional review of safety in acute cervical spine injury from 2013 to 2017

Samuel L. Malnik, Kyle W. Scott, M. Zino Kuhn, Dunbar Alcindor et autres

Objective: Halo vest immobilization (HVI) remains an important treatment option for occipital-cervical injuries. It provides the surgeon with a safe and effective medical treatment options for challenging patients. The aim of this study was to evaluate the safety of HVI in these …

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Inflammatory myofibroblastic tumor masquerading as an anterior choroidal artery fusiform aneurysm

Samuel L. Malnik, Rachel Moor, David Shin, Dimitri Laurent et autres

BACKGROUND: Inflammatory myofibroblastic tumor is a rare, poorly understood tumor that has been found to occur in almost every organ tissue. Its location within the central nervous system is uncommon, and patients tend to present with nonspecific symptoms. CASE DESCRIPTION: A female …

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Intracranial myxoid mesenchymal neoplasms with EWSR1 gene rearrangement: report of 2 midline cases with one demonstrating durable response to MET inhibitor monotherapy

Yanel De Los Santos, David Shin, Samuel L. Malnik, Marie Rivera‐Zengotita et autres

EWSR1 fusions have been identified in multiple neoplasms involving bone and soft tissue. Recently, cases of intracranial myxoid mesenchymal neoplasms harboring EWSR1-CREB family gene fusions have been reported in young patients with histologic features reminiscent of the myxoid variant of angiomatoid fibrous …

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High‐affinity interactions and signal transduction between Aβ oligomers and TREM2

Christian Lessard, Samuel L. Malnik, Yingyue Zhou, Thomas B. Ladd et autres

Rare coding variants in the triggering receptor expressed on myeloid cells 2 (TREM2) are associated with increased risk for Alzheimer's disease (AD), but how they confer this risk remains uncertain. We assessed binding of TREM2, AD-associated TREM2 variants to various forms of …

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