Derek Kennedy

1637P Efficacy of talazoparib and enzalutamide in mCRPC patients previously treated with androgen receptor pathway inhibitors (ARPI) or docetaxel: Post hoc analysis from both cohorts in TALAPRO-2 study

Neeraj Agarwal, Arun Azad, André Poisl Fay, N. Matsubara et autres

us, au, br, jp, it, kr, nz, fr, gb, de, no (code pays fourni par la source)

Dose selection for intracerebroventricular cerliponase alfa in children with CLN2 disease, translation from animal to human in a rare genetic disease

Kevin Hammon, Greg de Hart, Brian R. Vuillemenot, Derek Kennedy et autres

Abstract Neuronal ceroid lipofuscinosis type 2 (CLN2 disease) is an ultra‐rare pediatric neurodegenerative disorder characterized by deficiency of the lysosomal enzyme tripeptidyl peptidase‐1 (TPP1). In the absence of adequate TPP1, lysosomal storage material accumulation occurs in the central nervous system (CNS) accompanied …

us (code pays fourni par la source)

Ionizing radiation and toll like receptors: A systematic review article

Ali Mehdipour, Aliakbar Yousefi‐Ahmadipour, Derek Kennedy, Mohammad Kazemi Arababadi

ir, au (code pays fourni par la source)

Role of Chikungunya nsP3 in Regulating G3BP1 Activity, Stress Granule Formation and Drug Efficacy

Xue Mei Lu, Umber Alam, Charlene Willis, Derek Kennedy

au (code pays fourni par la source)

IL-8 May Be the Target of Arsenic in Human Breast Milk

Khodayar Ghorban, Maryam Dadmanesh, Mahmood Sheikh Fathollahi, Zeynab Rezai et autres

Background and Aims: The critical aim of this study was to evaluate the effects of breast-milk contamination with Nickel and Arsenic, as well as aflatoxin M1 (AFM1) on the milk levels of IL-6 and IL-8. Materials and Methods: Breast milk was collected …

ir, au (code pays fourni par la source)

G3BP1 and G3BP2 regulate translation of interferon-stimulated genes: IFITM1, IFITM2 and IFITM3 in the cancer cell line MCF7

Umber Alam, Derek Kennedy

au (code pays fourni par la source)

Psammaplysin F increases the efficacy of bortezomib and sorafenib through regulation of stress granule formation

K Christen, Rohan A. Davis, Derek Kennedy

au (code pays fourni par la source)

Rasputin a decade on and more promiscuous than ever? A review of G3BPs

Umber Alam, Derek Kennedy

Ras-GTPase-activating protein (SH3 domain)-binding proteins (G3BPs, also known as Rasputin) are a family of RNA binding proteins that regulate gene expression in response to environmental stresses by controlling mRNA stability and translation. G3BPs appear to facilitate this activity through their role in …

au (code pays fourni par la source)

Comparison of serum levels of IL-6, IL-8, TGF-β and TNF-α in coronary artery diseases, stable angina and participants with normal coronary artery

Zahra Sepehri, Mohammad Hadi Masoomi, Fatemeh Ruzbehi, Zohreh Kiani et autres

Cytokines, which typically regulate the immune responses, play a role in cardiovascular diseases such as coronary artery diseases (CAD) and ischemic heart diseases (IHD). The aims of this study were to evaluate serum levels of IL-6, IL-8, TGF-β and TNF-α in patients …

ir, au (code pays fourni par la source)

Interleukin-6 and Tumor Growth Factor–β are Risk Factors for Idiopathic Epistaxis

Soheila Rahmanzadeh-Shahi, Ali Golshiri-Isfahani, Mahmood Sheikh Fathollahi, Mohammad Taghi Rezayati et autres

OBJECTIVE: To evaluate the serum levels of interleukin (IL)-6, IL-8, tumor necrosis factor (TNF)-α, tumor growth factor (TGF)-β, endothelin, and immunoglobulin (Ig)E in patients with idiopathic epistaxis, compared with healthy control individuals. METHODS: Serum levels of IL-6, IL-8, TNF-α, TGF-β, endothelin, and …

ir, au (code pays fourni par la source)

Immunomodulatory effects of a rationally designed peptide mimetic of human IFNβ in EAE model of multiple sclerosis

Mansour Poorebrahim, Matin Asghari, Mohammad Foad Abazari, Hassan Askari et autres

ir, au (code pays fourni par la source)

Selective toxicity of hydroxyl-rich carbon nanodots for cancer research

Tak Hyun Kim, Joseph Sirdaarta, Qian Zhang, Ehsan Eftekhari et autres

The toxicity of nanoparticles in a biological system is an integration of effects arising from surface functionality, particle size, ionic dissolution, etc. This complexity suggests that generalization of a material’s toxicity may be inappropriate. Moreover, from a medicinal point of view, toxicity …

au (code pays fourni par la source)