M. A. Cherdak

Aging and Human Longevity. Volume 2. Edited by O.N. Tkacheva

О. Н. Ткачева, Maria S. Arefieva, S. L. Babak, Anna V. Balakina et autres

This publication addresses one of the most critical challenges in modern medicine: human aging and longevity. The authors have assembled the most current scientific knowledge on how the human body ages and how aging processes may be modulated. Volume Two explores demographic …

The patient pathway in the diagnosis and treatment of mild cognitive impairment and new therapeutic opportunities. Resolution of the Expert Council (Moscow, April 21, 2025)

О. Н. Ткачева, Elen A. Mkhitaryan, M. A. Cherdak, Yu. V. Zhitkova et autres

The Expert Council «The Patient Pathway in the Diagnosis and Treatment of Mild Cognitive Impairment (MCI) and New Therapeutic Opportunities» was held in Moscow on April 21, 2025. The purpose of the council was to discuss the challenges related to identifying patients …

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Differential Diagnosis of Alzheimer’s Disease and Vascular Cognitive Disorders

M. A. Cherdak, Elen A. Mkhitaryan

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Differential diagnosis of Alzheimer’s disease and vascular cognitive disorders

M. A. Cherdak, Elen A. Mkhitaryan, О. Н. Ткачева

Cognitive disorders (CD) are a common problem in the practice of various medical specialities. Among the most common causes of severe CD (dementia) are Alzheimer's disease (AD) and cerebrovascular diseases. The stage of non-dementia CD precedes dementia. Interventions at the non-dementia stage …

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Clinical guidelines «Cognitive disorders in the elderly and senile persons»

N. N. Yahno, Н. Г. Незнанов, Светлана Вячеславовна Шпорт, Nikolay A Shamalov et autres

Clinical guidelines «Cognitive disorders in the elderly and senile persons».

Aging and human longevity. Volume 1. Edited by O. N. Tkacheva

Anastasiia V. Badaeva, Arina E. Veriaskina, A. V. Vitebskaya, N. M. Vorobyeva et autres

The book Aging and Human Longevity edited by O.N. Tkacheva was authored by leading Russian gerontologists and geriatricians. It synthesizes both global and Russian advancements in the study of aging. The monograph is composed of two volumes, which systematically investigate the phenomenon …

On the Role of Sleep in the Aging Processes

R. I. Isaev, Elen A. Mkhitaryan, M. A. Cherdak, V. V. Vasilevskaya et autres

Abstract Sleep, as a fundamental requirement for the body’s well-being, plays a crucial role in various essential biological processes. Aging is one of the natural biological processes that affects all functions of the human body. The relationship between sleep and aging has …

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The role of sleep in the aging processes

R. I. Isaev, Elen A. Mkhitaryan, M. A. Cherdak, V. V. Vasilevskaya et autres

Sleep, being a fundamental requirement for the body’s well-being, plays a crucial role in various essential biological processes. Aging is one of the natural biological processes that affects all functions of the human body. The relationship between sleep and aging has been …

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Vitamin B12 Deficiency in Neurological Disorders of Older Adults: Etiology, Diagnostics, Treatment

M. A. Cherdak, Elen A. Mkhitaryan

One of the common problems associated with aging is vitamin B12 (cobalamin) deficiency. According to some reports, it is present in every third person over the age of 60. Cobalamin is involved in numerous biologically important reactions, and its deficiency manifests itself …

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Prevalence of cognitive impairment in older adults in the Russian Federation

M. A. Cherdak, Elen A. Mkhitaryan, Н. В. Шарашкина, Valentina S. Ostapenko et autres

Dementia is one of the main challenges to modern society. According to estimated data, as of 2019, there were 1.949.811 people living In Russia with dementia of various etiology. At the same time, there have been no large epidemiological studies of dementia …

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Clinical Guidelines for Perioperative Care of Older and Oldest-Old Patients Living with Frailty Undergoing Elective Surgery

О. Н. Ткачева, Н. К. Рунихина, Yu. V. Kotovskaya, Sergey R. Gilyarevsky et autres

The population of older and oldest-old individuals is increasing at a rapid pace, leading to a notable proportion of this age group requiring surgical procedures due to multimorbidity. It is known that, compared with young people, patients over 60 have a whole …

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Russian experience in using a combination of fixed doses of donepezil and memantine in the treatment of Alzheimer’s disease as an observational non-interventional multicenter program

Игорь Владимирович Колыхалов, Elen A. Mkhitaryan, Ya. B. Fedorova, Е. В. Пономарева et autres

OBJECTIVE: To evaluate the efficacy, safety, and compliance to therapy with Mioreol, first used as part of routine clinical practice in patients with moderate-to-severe dementia due to AD. MATERIAL AND METHODS: The study was conducted as a non-interventional observational program. The work …

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