D Gaillard

The Genotoxin Colibactin Shapes Gut Microbiota in Mice

Sophie Tronnet, Pauline Floch, Laetitia Lucarelli, D Gaillard et autres

Infections of genotoxic Escherichia coli spread concomitantly with urbanized progression. These bacteria may prompt cell senescence and affect DNA stability, inducing cancer via the production of colibactin, a genotoxin shown capable of affecting host DNA in eukaryotic cells. In this study, we …

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The Genotoxin Colibactin Shapes Gut Microbiota in Mice

Sophie Tronnet, Pauline Floch, Laetitia Lucarelli, D Gaillard et autres

fr (code pays fourni par la source)

Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917

Clémence Massip, Priscilla Branchu, Nadège Bossuet‐Greif, Camille V. Chagneau et autres

Although Escherichia coli Nissle 1917 (EcN) has been used therapeutically for over a century, the determinants of its probiotic properties remain elusive. EcN produces two siderophore-microcins (Mcc) responsible for an antagonistic activity against other Enterobacteriaceae. EcN also synthesizes the genotoxin colibactin encoded …

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An analysis of the role of cyclin dependant kinase inhibitor 1B (CDKN1B) gene mutations in 86 families with familial isolated pituitary adenomas (FIPA)

M. A. Tichomirova, Adrian Daly, J. Olmedo Pujol, Luciana Ansaneli Naves et autres

be, fr (code pays fourni par la source)

Economical Aspects Of ECC (Extracorporeal Circulation) In EEC(European Economical Community

A Lautier, D Gaillard, J.C. Sargentini, J.P. Gille et autres

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The Third Generation Of Artificial Lungs

A Lautier, J.P. Gille, A.M. Juvin, D Gaillard et autres

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[Cardiac surgery without transfusion in 2005].

Claude D. Vaislic, Olivier Michel Bical, P Deleuze, Wassim Khoury et autres

PURPOSE: Between January 1991 and October 2003, 200 Jehovah Witnesses adult patients underwent elective cardiac surgery. To asses the impact on continuing progress of blood saving protocols and the increasing operative risk of patients proposed to surgery, we have re-assessed our results …

Monitoring of heat-lung machine with continuous blood-gas measurement

A Lautier, T. Dehe, D Gaillard, A.M. Juvin et autres

Microcomputer software that allows continuous acquisition of extracorporeal circulation (ECC) parameters, namely blood gases and temperature in arteries and/or veins, blood flow rate, gas flow rate, percent of expired CO/sub 2/ and gaseous mixture, is described. Its purpose is to facilitate control …

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Does Warm Antegrade Intermittent Blood Cardioplegia Really Protect the Heart during Coronary Surgery?

Olivier Michel Bical, Y. Frames, Danièle Paumier, D Gaillard et autres

Objective: Intermittent antegrade blood cardioplegia (IABC) has been standardized as a routine technique for myocardial protection in coronary surgery. However, if the myocardium is known to tolerate short periods of ischemia during hypothermic arrest, it may be less tolerant of warm ischemia, …

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Twelve novel mutations (Y11C, A34V, R54H, R135H, N194D, G203V, E218G, D277Y, F310G, 998-1T, A382S, V406A) in the tissue-non specific alkaline phosphatase (TNSALP) gene in patients with various forms of Hypophosphatasia.

Agnes Taillandier, Anne-Sophie Lia-Baldini, Marie-Laure Mouchard, Blaise Robin et autres

International audience

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A review of myocardial normothermia: its theoretical basis and the potential clinical benefits in cardiac surgery

D Gaillard

Myocardial protection during cardiac surgery aims to preserve myocardial function while providing a bloodless and motionless operating field to make surgery easier. Myocardial protection is achieved by decreasing the oxygen needs using hypothermia and producing electromechanical cardiac arrest using potassium infusion which …

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[Diagnosis of meconium ileus].

D Gaillard

Meconium ileus represents a functional disorder mainly detected during the second trimester of gestation. The diagnosis can be recognized by bowel hyperechogenicity or by the pathologist after a systematic examination. It must lead to etiologic diagnosis and specific investigations according to the …

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