Accès ouvert
2026
dataset
OpenAlex
Renato Pascale, Mena Gallo, Nicolò Regge Gianas, Giacomo Fornaro et autres
Dataset associated with the paper "Risk factors for treatment failure of surgical site deep infections following spinal instrumentation: multicentre observational study (DeFEndO Study)" This set of raw data cannot be made publicly available as including sensitive information, but might be available to …
it
(code pays fourni par la source)
Accès ouvert
2026
dataset
OpenAlex
Renato Pascale, Mena Gallo, Nicolò Regge Gianas, Giacomo Fornaro et autres
Dataset associated with the paper "Risk factors for treatment failure of surgical site deep infections following spinal instrumentation: multicentre observational study (DeFEndO Study)" This set of raw data cannot be made publicly available as including sensitive information, but might be available to …
it
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Sara Tedeschi, Marta Fernández-Sampedro, Eleonora Zamparini, Nicolò Rossi et autres
Abstract Background Empirical broad-spectrum antibiotic therapy is currently recommended for patients undergoing surgical treatment of prosthetic joint infections (PJIs), while awaiting intraoperative culture results. However, widespread use of Gram-negative coverage may lead to more adverse reactions, resistance selections and costs. Objectives This …
it, es
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Accès ouvert
2026
article
OpenAlex
Cecilia Bonazzetti, Marco Falcone, Giusy Tiseo, Francesco Di Gennaro et autres
ABSTRACT Cefepime/enmetazobactam (FEP/META) is a novel β-lactam/β-lactamase inhibitor combination with activity against Enterobacterales, including extended-spectrum β-lactamase-producing isolates, but real-world clinical data outside randomized trials remain limited. We conducted a retrospective multicenter descriptive study across 13 Italian hospitals. Eligible patients had infections caused …
it, es, by, mm, us
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Accès ouvert
2026
article
OpenAlex
Manjunath P. Pai, Pier Giorgio Cojutti, Riccardo De Paola, Eleonora Zamparini et autres
OBJECTIVES: Dalbavancin is increasingly used off-label for complicated methicillin-resistant Staphylococcus aureus infections requiring prolonged antimicrobial exposure. However, approved dosing regimens were developed for short-course therapy and may provide inadequate exposure in patients with obesity or preserved kidney function. We aimed to develop …
us, it
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Accès ouvert
2026
article
OpenAlex
Alice Toschi, Beatrice Profiti, Zeno Adrien Igor Pasquini, Sara Tedeschi et autres
Abstract Objective: To describe an outbreak of OXA-48–like producing Escherichia coli in a hematology ward and the infection prevention and control (IPC) measures implemented to contain it. Design: Prospective observational study. Setting: Hematological ward of a tertiary public hospital. Patients: Hematological patients. …
it
(code pays fourni par la source)
2025
article
OpenAlex
Giacomo Fornaro, Sara Tedeschi, Eleonora Zamparini, Eric L. Staals et autres
AIM To present a case of chronic osteomyelitis caused by Scedosporium apiospermium, highlighting the therapeutic challenge of this rare condition. Scedosporium is a fungus that can cause severe disease in immunocompromised patients, with high mortality, and compartmentalized infections following direct inoculation in …
it
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Accès ouvert
2025
article
OpenAlex
Milo Gatti, Matteo Rinaldi, Pier Giorgio Cojutti, Cecilia Bonazzetti et autres
ABSTRACT To assess the impact of a multidisciplinary approach aimed at attaining aggressive joint pharmacokinetic/pharmacodynamic (PK/PD) target with ceftazidime/avibactam on treatment outcome of KPC- Klebsiella pneumoniae (Kp) infections and prevention of ceftazidime/avibactam resistance development, a pre-post quasi-experimental study on adult patients with …
it
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Accès ouvert
2025
article
OpenAlex
Sara Tedeschi, Efthymia Giannitsioti, Christian Mayer
Due to the involvement of biofilms in the pathogenesis of bone and joint infections (BJI), the treatment of these infections is often challenging, especially when multidrug- or extensively drug-resistant (MDR/XDR) pathogens are involved. Intravenous fosfomycin (FOS) is a phosphoenolpyruvate analogue with a …
it, gr, de
(code pays fourni par la source)
2025
article
OpenAlex
Laura Cucinella, Chiara Cassani, Sara Tedeschi, Stefano Memoli et autres
INTRODUCTION: Fezolinetant is a first-in-class non-hormonal pharmacological treatment recently approved for moderate-to-severe vasomotor symptoms (VMS) associated with menopause. Its mechanism of action selectively targets the pathophysiology of VMS at hypothalamic level, antagonizing binding of neurokinin B, overexpressed in estrogen deprived menopausal women, …
it
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Accès ouvert
2025
article
OpenAlex
Pier Giorgio Cojutti, Sara Tedeschi, Eleonora Zamparini, Giacomo Fornaro et autres
Background: Daptomycin plus fosfomycin combination therapy is a valuable strategy for treating staphylococcal osteoarticular infections (OIs), but hypernatremia and hypokalemia due to sodium overload are important issues. The aim of this study was to assess the likelihood of attaining a pharmacokinetic/pharmacodynamic (PK/PD) …
it
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Accès ouvert
2024
article
OpenAlex
Sara Tedeschi, Nicolò Rossi, Eleonora Zamparini, Simone Ambretti et autres
Objectives: The main aim of this study was to describe the epidemiology of infected non-unions (INUs) managed at an Infectious Disease (ID) referral centre and to investigate the factors associated with treatment failure. Methods: This was an observational retrospective study on adult …
it
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