Ryan Rose

Once, twice, three times frozen: viability and post-transfer outcomes of fresh and vitrified-warmed mouse embryos

Tong Li, D J X Chow, S.J. Li, Ryan Rose et autres

STUDY QUESTION: What is the impact of one, two, or three vitrification-warming cycles on embryo viability, implantation potential, and post-transfer development compared with fresh transfer? SUMMARY ANSWER: Repeated vitrification-warming cycles progressively impaired embryo cryosurvival, blastocyst quality, and foetal growth after two or …

au (code pays fourni par la source)

HIF-2α expression is controlled by the progesterone receptor and regulates hCG-induced gene expression in granulosa cells during ovulation in mice

Alison E. Roennfeldt, Doan T. Dinh, Timothy R. McPhee, Ryan Rose et autres

au (code pays fourni par la source)

AMH regulates ovary size by counteracting the positive influence of clustered ovarian follicle growth

Carmen Lim, Lynn Yiew, Nicholas J. Anderson, Peter R. Smith et autres

STUDY QUESTION: Does anti-Müllerian hormone (AMH) influence preantral follicle development within a short range of AMH-secreting antral follicles? SUMMARY ANSWER: Immunization of sheep against AMH leads to increased follicle survival, specifically in regions close to small-medium antral follicles. WHAT IS KNOWN ALREADY: …

nz, au (code pays fourni par la source)

Telomere length in offspring is determined by mitochondrial-nuclear communication at fertilization

Yasmyn E. Winstanley, Ryan Rose, Alexander P. Sobinoff, Linda Wu et autres

Abstract The initial setting of telomere length during early life in each individual has a major influence on lifetime risk of aging-associated diseases; however there is limited knowledge of biological signals that regulate inheritance of telomere length, and whether it is modifiable …

au, us (code pays fourni par la source)

The Pipette and the Pressure: Assessing Stress Levels in Embryologists Special Interest Group—Embryology, ASPIRE

Gaurav Mittal, Krishna Mantravadi, Keshav Malhotra, Kenji Ezoe et autres

Background: Embryologists are critical in assisted reproductive technology (ART) treatments, managing procedures that directly impact clinical outcomes. Despite the importance and high-pressure nature of their jobs, the impact of their stressors is poorly known. This Asia Pacific Initiative on Reproduction (ASPIRE)-led study …

in, jp, hk, us, kr, au (code pays fourni par la source)

Sperm oxidative damage acquired during seminal plasma removal for assisted reproductive technology is reduced by BGP-15

Macarena B. Gonzalez, Ryan Rose, Haley S. Connaughton, Caitlyn Bugeja et autres

PURPOSE: Semen manipulation for assisted reproductive technology (ART) causes spermatozoa damage; thus, we investigated the potential of the novel therapeutic BGP-15 to preserve sperm quality during semen washing prior to insemination. METHODS: Donated human ejaculates (N = 40), with or without 10 …

au (code pays fourni par la source)

HIF-2α Expression Is Controlled by the Progesterone Receptor and Regulates Gene Expression in Granulosa Cells during Ovulation in Mice

Alison E. Roennfeldt, Thao D. Dinh, Timothy R. McPhee, Ryan Rose et autres

au (code pays fourni par la source)

Mitochondrial activator BGP-15 protects sperm quality against oxidative damage and improves embryo developmental competence

Macarena B. Gonzalez, Nicole Olivia McPherson, Haley S. Connaughton, Yasmyn E. Winstanley et autres

OBJECTIVE: To study the efficacy of mitochondrial activator BGP-15 to preserve sperm quality and competence against cellular damage. DESIGN: Spermatozoa from mice or humans were treated in vitro with BGP-15, and sperm quality markers were assessed. Spermatozoa from young (8-12 weeks old) …

au (code pays fourni par la source)

AMH regulates ovary size by counteracting ovarian follicle cluster effects.

Carmen C. W. Lim, Lynn Yiew, Nicholas J. Anderson, Peter R. Smith et autres

Serum anti-Mullerian hormone (AMH) is the primary clinical indicator of mature oocyte counts in the ovaries, but its biological role remains poorly understood. Mammalian ovaries have a finite lifetime of oocytes that are slowly depleted as the dormant follicles housing the oocytes …

nz, au (code pays fourni par la source)

Granulosa cell metabolism at ovulation correlates with oocyte competence and is disrupted by obesity and aging

Atsushi Morimoto, Ryan Rose, Kirsten M. Smith, Doan T. Dinh et autres

STUDY QUESTION: Is oocyte developmental competence associated with changes in granulosa cell (GC) metabolism? SUMMARY ANSWER: GC metabolism is regulated by the LH surge, altered by obesity and reproductive aging, and, in women, specific metabolic profiles are associated with failed fertilization versus …

au, jp (code pays fourni par la source)

Physeal Closure and Fracture Pattern in Adolescent Transitional Distal Radius Fractures

Gus Strauss, Jacob Brennan, David Momtaz, Abdullah N. Ghali et autres

PURPOSE: To show a correlation between grade of physeal closure and fracture pattern in adolescent transitional distal radius fractures. METHODS: A retrospective chart review was performed of 490 distal radius fractures, ages 14 to 18, at a single institution between 2007 and …

us (code pays fourni par la source)

#252 : Granulosa Cell Metabolism is Differentially Impacted by Obesity and Aging and Correlated With Oocyte Competence

Atsushi Morimoto, Ryan Rose, Kirsten S. Smith, Doan T. Dinh et autres

Background and Aims: Aging and obesity are associated with female infertility, with mitochondrial dysfunction proposed as an underlying factor; but our understanding of energy metabolism within the ovary remains limited. Method: This study focused on the granulosa cells surrounding the oocyte and …

jp, au (code pays fourni par la source)