Sophie Paget‐Bailly

Germline BRCA1/2 Mutations in a Large Clinic-Based Cohort of Patients with Metastatic Breast Cancer in France

Guillaume Meynard, Victor Pereira, Sophie Paget‐Bailly, Élodie Klajer et autres

Objectives: This study aimed to fill the data gap regarding the prevalence of germline (g) BRCA1/2 mutations in patients with metastatic breast cancer (mBC) in France. Methods: A prospective gBRCA1/BRCA2 mutation analysis was proposed to all patients with mBC treated in seven …

fr (code pays fourni par la source)

Effect of a supervised intermittent exercise program on insomnia in breast cancer patients undergoing chemotherapy

Chloé Drozd, Elsa Curtit, Quentin Jacquinot, Pauline Roux et autres

Abstract Background Patients with localized breast cancer receiving adjuvant chemotherapy often experience sleep disturbances, especially insomnia, which significantly impacts quality of life. This study primarily aimed to evaluate the effects of a 12-week exercise program on insomnia, with secondary outcomes on sleep …

fr (code pays fourni par la source)

Réentraînement à l’exercice : effets sur l’insomnie, chez des patientes atteintes d’un cancer du sein, non métastatique, en cours de chimiothérapie

Chloé Drozd, Elsa Curtit, Quentin Jacquinot, Sophie Paget‐Bailly et autres

fr (code pays fourni par la source)

Postcancer rehabilitation: multidisciplinary exercise – programme organisation and feasibility

Chloé Drozd, Quentin Jacquinot, Sophie Paget‐Bailly, Laura Mansi et autres

BACKGROUND: Although the benefit of supportive care in the postcancer period is now well demonstrated, its implementation in the patient journey remains challenging. This article describes the development, since 2015 and in routine care, of supportive postcancer care comprising a multidisciplinary rehabilitation …

fr (code pays fourni par la source)

Prevalence and Characteristics of Sleep Apnea in Intensive Care Unit Survivors After SARS-CoV-2 Pneumonia

Ibrahim Traoré, Guillaume Eberst, Fréderic Claudé, Lucie Laurent et autres

Background: Sleep apnea (SA) was reported as possibly exacerbating symptoms of COVID-19, a disease induced by SARS-CoV-2 virus. The same comorbidities are common with both pathologies. This study aimed to estimate the prevalence, characteristics of SA and variation in AHI three months …

fr, au (code pays fourni par la source)

HERibuline: Eribulin mesylate and Trastuzumab in pretreated HER2-positive advanced breast cancer—A report of region’s practice.

Noémie Gassian, Sophie Paget‐Bailly, O. Djoumakh, Laura Mansi et autres

e13020 Background: Until 2020, in human epidermal growth factor receptor 2 (HER2)-positive advanced breast cancer (ABC), the two first lines of metastatic treatment were well defined but after, many options were possible, most often combining targeted therapy plus chemotherapy. Eribulin mesylate is …

fr (code pays fourni par la source)

Result of one-year, prospective follow-up of intensive care unit survivors after SARS-CoV-2 pneumonia

Guillaume Eberst, Fréderic Claudé, Lucie Laurent, Aurélia Meurisse et autres

INTRODUCTION: Survivors of viral ARDS are at risk of long-term physical, functional and neuropsychological complications resulting from the lung injury itself, but also from potential multiorgan dysfunction, and the long stay in the intensive care unit (ICU). Recovery profiles after severe SARS-CoV-2 …

fr, au (code pays fourni par la source)

HPV16 Load Is a Potential Biomarker to Predict Risk of High-Grade Cervical Lesions in High-Risk HPV-Infected Women: A Large Longitudinal French Hospital-Based Cohort Study

Antoine Baumann, Julie Henriques, Zohair Selmani, Aurélia Meurisse et autres

High-risk HPV (hrHPV) testing has been implemented as a primary screening tool for cervical cancer in numerous countries. However, there is still a need for relevant triage strategies to manage hrHPV positive women to avoid excessive referral to colposcopy. The objective of …

fr (code pays fourni par la source)

Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer

Roberto Ferrara, Martina Imbimbo, Reem Malouf, Sophie Paget‐Bailly et autres

BACKGROUND: Immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis have changed the first-line treatment of people with advanced non-small cell lung cancer (NSCLC). Single-agent pembrolizumab (a PD-1 inhibitor) is currently the standard of care as monotherapy in patients with PD-L1 expression ≥ …

it, ch, gb, fr (code pays fourni par la source)

An international tool to measure perceived stressors in intensive care units: the PS-ICU scale

Alexandra Laurent, Alicia Fournier, Florent Lheureux, M.C. Martín Delgado et autres

BACKGROUND: The intensive care unit is increasingly recognized as a stressful environment for healthcare professionals. This context has an impact on the health of these professionals but also on the quality of their personal and professional life. However, there is currently no …

fr, es, it, ca (code pays fourni par la source)

Feasibility of a prehabilitation programme dedicated to older patients with cancer before complex medical–surgical procedures: the PROADAPT pilot study protocol

Mélanie Roche, Christine Ravot, Amélie Malapert, Sophie Paget‐Bailly et autres

BACKGROUND: Ageing is associated with an increased prevalence of comorbidities and sarcopenia as well as a decline of functional reserve of multiple organ systems, which may lead, in the context of the disease-related and/or treatment-related stress, to functional deconditioning. The multicomponent 'Prehabilitation …

fr (code pays fourni par la source)

Feasibility of health-related quality of life (HRQoL) assessment for cancer patients using electronic patient-reported outcome (ePRO) in daily clinical practice

Guillaume Mouillet, Antoine Falcoz, J. Fritzsch, Hamadi Almotlak et autres

fr (code pays fourni par la source)