3′-Amino modifications enhance the antifungal properties of N 4 -alkyl-5-methylcytidines for potential biocides
Liudmila A. Alexandrova, Oleg V. Shevchenko, Maxim V. Jasko, Pavel N. Solyev et autres
A set of 3′-modified N 4 -alkyl-5-methyl-2′-deoxycytidines has been synthesized and evaluated for biological activity. The replacement of the 3′-hydroxyl group with amino, aminoethyl and dialkylamino groups significantly enhances antifungal activity.
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15 citations
New Journal of Chemistry