Donna Crabtree

Apolipoprotein E Mimetic Peptide CN-105 and Postoperative Delirium in Older Patients

Noah J. Timko, Mary Cooter Wright, Melody R. Smith, Piper C. Boykin et autres

Importance: The apolipoprotein E (APOE) gene ε4 allele leads to increased Alzheimer disease risk and neuroinflammation and is also believed to play a role in postoperative delirium. However, the safety and feasibility of modulating apoE protein signaling to reduce postoperative neuroinflammation and …

us, gb, se, cn, fr, gr (code pays fourni par la source)

IMPLEMENTATION SCIENCE FRAMEWORK-GUIDED ASSESSMENT OF CLINICIAN STRATEGIES TO IMPROVE EQUITABLE ACCESS TO PENICILLIN ALLERGY DE-LABELING

Donna Crabtree, Olabimpe Asupoto, Denise H. Daudelin, Stephan Bartels et autres

Supplemental Figure Legends from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Supplemental Figure Legends

Supplemental Figure 5 from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Brain distribution of Elacridar in ABC KO and ABC WT is not significantly different.

Supplemental Figure 6 from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Elacridar does not significantly impact dasatinib delivery in absence of ABCG2 and ABCB1

Supplemental Figure 3 from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Representative images of four dasatinib-treated murine brainstem gliomas in ABC KO and ABC WT mice (10X and 40X images).

Supplemental Figure 2 from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Graph depicting fold change of Abcg2, Abcb1a, and Abcb1b transcripts of nestin-expressing brainstem progenitors, ABC KO tumor cell-lines, and ABC WT tumor cell-lines

Supplemental Figure 4 from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Representative images of four vehicle-treated murine brainstem gliomas in ABC KO and ABC WT mice (10X and 40X images).

Supplemental Figure 1 from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Schematic of the survival study including a cartoon demonstrating the methodology for tumor generation

Supplemental Figure Legends from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Supplemental Figure Legends

Supplemental Figure 2 from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Graph depicting fold change of Abcg2, Abcb1a, and Abcb1b transcripts of nestin-expressing brainstem progenitors, ABC KO tumor cell-lines, and ABC WT tumor cell-lines

Supplemental Figure 1 from ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree, Kyle G. Halvorson et autres

Schematic of the survival study including a cartoon demonstrating the methodology for tumor generation