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Marc C. Chamberlain, Lisa Chalmers
BACKGROUND: Acute binocular blindness is an uncommon cause for neurologic consultation. METHODS: Over the last 20 months 10 patients with acute onset blindness were seen at a tertiary cancer center. Probable cause was identified in all patients. RESULTS: Treatment varied and was …
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Sajeel Chowdhary, Lisa Chalmers, Marc C. Chamberlain
In the course of 1 year at a tertiary cancer center, 3 patients (2 men; 1 woman; age 51-75 years) were seen in neurological consultation (1.5% of all consultations). Clinical course in all patients was of a progressive neurologic disorder not consistent …
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Marc C. Chamberlain, Lisa Chalmers
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Marc C. Chamberlain, Michael Glantz, Lisa Chalmers, Alixis Van Horn et autres
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Sajeel Chowdhary, Lisa Chalmers, P. A. Marc Chamberlain
A 36-year-old man with acute lymphoblastic leukemia developed recurrence treated with busulfan and fludarabine followed by transplantation. Disease recurred as leukemic meningitis for which an Ommaya reservoir was placed. Following his sixth intraventricular methotrexate treatment, the patient developed acute confusion and a …
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Myke R. Green, Sajeel Chowdhary, Lisa Chalmers, Kris M Lombardi et autres
High-dose methotrexate (HDMTX) forms the basis for the majority of chemotherapy regimens for primary CNS lymphoma. Several toxicities are encountered with HDMTX, of most concern is acute nephrotoxicity. This case report illustrates several aspects of HDMTX-related renal injury.
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JOHN A. ROBB, Lisa Chalmers, Amyn M. Rojiani, Marc C. Chamberlain
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Myke R. Green, Sajeel Chowdhary, Lisa Chalmers, Kris M Lombardi et autres
Marc C. Chamberlain, Michael Glantz, Lisa Chalmers, Alixis Van Horn et autres
1513 Background: Concurrent temozolomide (TMZ) and radiotherapy (RT) is the new standard of care for patients with newly diagnosed glioblastoma GBM). This report is a prospective observational study of surgically confirmed early necrosis in adult patients with GBM treated with concurrent TMZ …
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Myke R. Green, Sajeel Chowdhary, Kristina M Lombardi, Lisa Chalmers et autres
Primary CNS non-Hodgkin lymphoma (PCNSL) has been shown to be increasing in incidence. This appears to be a consequence of the increasing population of those older than 65 years of age in whom PCNSL occurs most often. PCNSL often has a favorable …
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Myke R. Green, Sajeel Chowdhary, Lisa Chalmers, Kris M Lombardi et autres
High-dose methotrexate (HDMTX) forms the basis for the majority of chemotherapy regimens for primary CNS lymphoma. Several toxicities are encountered with HDMTX, of most concern is acute nephrotoxicity. This case report illustrates several aspects of HDMTX-related renal injury.
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