Sonia Ktari

Genomic surveillance of invasive Streptococcus pneumoniae strains in south Tunisia during 2012–2022

Fahmi Smaoui, Boutheina Ksibi, N. Ben Ayed, Sonia Ktari et autres

Purpose. Invasive pneumococcal disease (IPD) remains a major global public health concern due to its high morbidity and mortality rates, particularly among children and the elderly. This study aimed to apply whole-genome sequencing (WGS) to characterize Streptococcus pneumoniae strains responsible for IPD …

Tunisie (code pays fourni par la source)

Genome-based assessment of antimicrobial resistance, virulence-associated genes, and prophage diversity across clinical Salmonella Typhimurium isolates in the south of Tunisia

Sonia Ktari, Fahmi Smaoui, Boutheina Ksibi, Sonda Maalej et autres

Tunisie, fr (code pays fourni par la source)

Molecular epidemiology of a multidrug-resistant Shigella sonnei outbreak in Tunisia (2022–2023) using whole-genome sequencing

Fahmi Smaoui, Boutheina Ksibi, Senda Mezghani, Fatma Charfi et autres

Purpose. The prevalence of multidrug-resistant (MDR) Shigella sonnei is increasing globally, raising concerns for public health. In 2022, an outbreak of MDR S. sonnei was observed in Tunisia. We aimed to evaluate the genetic profile of S. sonnei isolates during the outbreak, …

Tunisie (code pays fourni par la source)

Genomic analysis of Brucella melitensis isolates recovered from humans in south Tunisia over 35 years between 1988 and 2022

Boutheina Ksibi, Fahmi Smaoui, Nourelhouda Ben Ayed, M. Guetat et autres

Brucella melitensis is a zoonotic pathogen that poses a worldwide public health challenge. In recent years, whole-genome sequencing has become a widely accepted molecular typing method for the genomic epidemiology of brucellosis. This study reports the genomic characteristics of 24 B. melitensis …

Tunisie (code pays fourni par la source)

The Evolution of the Antimicrobial Resistance of Streptococcus pneumoniae in Tunisia: A Multicentric Analysis over Two Decades (2000–2019)

Nourelhouda Ben Ayed, Omar Gargouri, Samar Mhimdi, Fahmi Smaoui et autres

Background/Objectives: Streptococcus pneumoniae is a leading respiratory pathogen responsible for significant morbidity and mortality, particularly among vulnerable populations. Understanding its antimicrobial resistance patterns and serotype distribution is crucial for guiding treatment and prevention strategies. This study aims to examine these trends in …

Tunisie, us (code pays fourni par la source)

Nasopharyngeal Carriage of Streptococcus pneumoniae in Tunisian Healthy under-Five Children during a Three-Year Survey Period (2020 to 2022)

Nourelhouda Ben Ayed, Sonia Ktari, Jihen Jdidi, Omar Gargouri et autres

We aimed to assess the prevalence of nasopharyngeal pneumococcal carriage and to determine serotype distribution, antibiotic susceptibility patterns, and evolutionary dynamics of Streptococcus pneumoniae isolates in healthy under-five children. Nasopharyngeal swabs were collected from healthy children over three survey periods between 2020 …

Tunisie (code pays fourni par la source)

Group B Streptococcus and Perinatality in the South of Tunisia: Epidemiology, Serotype Distribution, and Antibiotic Susceptibility

Rim Kharrat, Nourelhouda Ben Ayed, Sonia Ktari, Chiraz Regaieg et autres

INTRODUCTION: (GBS) in pregnant women and newborns. MATERIALS AND METHODS: A retrospective analysis of GBS neonatal invasive infections and a cross-sectional study evaluating the prevalence of maternal GBS colonization were conducted. GBS isolates were tested for antimicrobial susceptibility, serotyped, and assessed for …

Tunisie (code pays fourni par la source)

Antibiotic resistance pattern, capsular types, and molecular characterization of invasive isolates of Streptococcus pneumoniae in the south of Tunisia from 2012 to 2018

Sonia Ktari, Nourelhouda Ben Ayed, Imen Ben Rbeh, Nourhène Garbi et autres

BACKGROUND: Streptococcus pneumoniae remains a leading cause of morbidity and mortality worldwide. In this study, we sought to analyze serotype distributions, antibiotic resistance, and genetic relationships of 106 clinical invasive pneumococcal isolates recovered in Tunisia between 2012 and 2018, prior to the …

Tunisie (code pays fourni par la source)

PP128 [Infections » Sepsis]: NEONATAL GROUP B STREPTOCOCCAL DISEASE IN SFAX, TUNISIA: EPIDEMIOLOGY, SEROTYPES AND ANTIBIOTIC SUSCEPTIBILITY OF ISOLATES

Chiraz Regaieg, Rania Kharrat, N. Ben Ayed, Sonia Ktari et autres

Regaieg, C.; Kharrat, R.; Ben Ayed, N.; Ktari, S.; Afef, B.; Abdellatif, G.; Adnene, H. Author Information

Tunisie (code pays fourni par la source)

Antimicrobial resistance genes, virulence markers and prophage sequences in Salmonella enterica serovar Enteritidis isolated in Tunisia using whole genome sequencing

Boutheina Ksibi, Sonia Ktari, Kaïs Ghedira, Houcemeddine Othman et autres

Salmonella Enteritidis causes a major public health problem in the world. Whole genome sequencing can give us a lot of information not only about the phylogenetic relatedness of these bacteria but also in antimicrobial resistance and virulence gene predictions. In this study, …

Tunisie, Afrique du Sud, fr (code pays fourni par la source)

MDR1 Haplotypes and G2677T/A Polymorphism Predict Imatinib Response in Tunisian Patients with Chronic Myeloid Leukemia

Mariam Ammar, Sonia Ktari, Moez Medhaffar, Hanène Ghozzi et autres

Background: The role of human multidrug resistance gene (MDR1) SNPs in the interindividual variability of imatinib mesylate (IM) response has received considerable attention. We aimed to study the association between SNPs of the MDR1 gene (C1236T, G2677T/A, C3435T) and IM response in …

Tunisie (code pays fourni par la source)

Relationship Between Serotypes and Antimicrobial Nonsusceptibility of Streptococcus pneumoniae Clinical Isolates in Tunisia

Nourelhouda Ben Ayed, Sonia Ktari, Sonda Mezghani, Basma Mnif et autres

Streptococcus pneumoniae remains a significant cause of morbidity and mortality worldwide despite the overall success of the vaccine programs. In Tunisia, pneumococcal conjugate vaccines (PCV)10 was introduced in the national immunization program in April 2019. We sought to determine the relationship between …

Tunisie (code pays fourni par la source)