Sylvie Tissier

FOXJ1 transcriptional targets in human airway cells and impaired multiciliogenesis in FOXJ1 -associated primary ciliary dyskinesia

Lucie Thomas, Jacques Serizay, Rahma Mani, Sandrine Couvet et autres

Fluid mobilization on epithelia is ensured by the motile cilia of differentiated multiciliated cells (MCCs). Key transcriptional regulators of motile ciliogenesis include CCNO, MCIDAS, RFXs, and the transcription factor FOXJ1, whose precise role in humans remains unclear. We show that, unlike CCNO …

fr (code pays fourni par la source)

Prognostic stratification and predictive performance of stress CMR in a Secondary Prevention Cohort: Insights from the Nancy Ischemia Registry

zukaï chati, Sylvie Tissier, Clémence BALAJ, Marie Lafitte et autres

fr (code pays fourni par la source)

Impact of screening for myocardial ischemia and revascularization on cardiovascular outcomes: Insights from the Nancy ischemia registry

zukaï chati, Sylvie Tissier, Clémence BALAJ, N. Benzaghou et autres

fr (code pays fourni par la source)

How could “Nancy Ischemia Registry Algorithm” guide, in a real world, the choice of an anatomical or functional imaging test in the screening of myocardial ischemia?

zukaï chati, Sylvie Tissier, Clémence BALAJ, M Laffitte et autres

fr (code pays fourni par la source)

Two-year follow-up of myocardial revascularization after anatomical and functional screening for myocardial ischemia: Insights from the “Nancy Ischemia Registry”

zukaï chati, Sylvie Tissier, Clémence BALAJ, Marianne Lafitte et autres

Skewed X-chromosome inactivation drives the proportion of DNAAF6-defective airway motile cilia and variable expressivity in primary ciliary dyskinesia

Lucie Thomas, Laurence Cuisset, Jean-François Papon, Aline Tamalet et autres

International audience

Skewed X-chromosome inactivation drives the proportion of DNAAF6-defective airway motile cilia and variable expressivity in primary ciliary dyskinesia

Lucie Thomas, Laurence Cuisset, Jean‐François Papon, Aline Tamalet et autres

Background Primary ciliary dyskinesia (PCD) is a rare airway disorder caused by defective motile cilia. Only male patients have been reported with pathogenic mutations in X-linked DNAAF6, which result in the absence of ciliary dynein arms, whereas their heterozygous mothers are supposedly …

fr (code pays fourni par la source)

Nancy ischemia register: Stress CMR vs. Stress Echo.Realistic evidence in the detection of myocardial ischemia

zukaï chati, Sylvie Tissier, Clémence BALAJ, N. Benzaghou et autres

fr (code pays fourni par la source)

TTC12 Loss-of-Function Mutations Cause Primary Ciliary Dyskinesia and Unveil Distinct Dynein Assembly Mechanisms in Motile Cilia Versus Flagella

Lucie Thomas, Khaled Bouhouche, Marjorie Whitfield, Guillaume Thouvenin et autres

fr (code pays fourni par la source)

Primary ciliary dyskinesia gene contribution in Tunisia: Identification of a major Mediterranean allele

Rahma Mani, Sabrina Belkacem, Zohra Soua, Sandra Chantot‐Bastaraud et autres

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disease of motile cilia. Even though PCD is widely studied, North-African patients have been rarely explored. In this study, we aim at confirming the clinical diagnosis and explore the genetic spectrum of PCD in …

fr, Tunisie (code pays fourni par la source)

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia

Marjorie Whitfield, Lucie Thomas, Émilie Béquignon, Alain Schmitt et autres

fr (code pays fourni par la source)

L’analyse quantitative du mouvement ciliaire permet d’identifier le phénotype ultra-structural des dyskinésies ciliaires primitives

Sylvain Blanchon, Marie Legendre, Mathieu Bottier, Aline Tamalet et autres

fr (code pays fourni par la source)