Rafał Szewczyk

Enzymatic biodegradation of poly(butylene adipate-co-terephthalate) (PBAT) microplastic by Trichoderma harzianum KKP534

Olga Rusiecka, Katarzyna Hrynkiewicz, Grzegorz Trykowski, Rafał Szewczyk et autres

• Incubation with Trichoderma led to the formation of cracks on the surface of the PBAT. • Trichoderma effectively colonises and produces numerous spores on the surface of PBAT. • Trichoderma produces a set of enzymes with degradation potential towards PBAT. • …

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Proteomic Analysis of Serum in Cardiac Transthyretin Amyloidosis: Diagnostic and Prognostic Implications for Biomarker Discovery

Joanna Waś, Monika Gawor-Prokopczyk, Agnieszka Sioma, Rafał Szewczyk et autres

Background/Objectives: Having serum biomarkers available for cardiac transthyretin amyloidosis (ATTR-CA) would be beneficial for diagnosis and prognosis. This study aimed to identify potential ATTR-CA biomarkers through proteomic analysis. Patients and Methods: Serum proteomic analyses were conducted on 15 ATTR-CA patients before receiving …

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Detection and accurate identification of Mycobacterium species by flow injection tandem mass spectrometry (FIA-MS/MS) analysis of mycolic acids

Rafał Szewczyk, Magdalena Druszczyńska, Szulc Bartłomiej, Kowalski Konrad

Mycolic acids, long-chain α-alkyl, β-hydroxy fatty acids, are characteristic for the genus Mycobacterium and play a critical role in the structural integrity and pathogenicity of mycobacterial cell walls. The unique structural diversity of mycolic acids among various Mycobacterium species offers a reliable …

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Proteins Obtained from Dunaliella Salina Algae and Their Application in Gelation Processes and Metal Binding Compared to Legume Proteins

Rafał Szewczyk

Aim: Identification of research gap regarding the functional properties of microalgal proteins, specifically Dunaliella salina. The analysis aimed to determine whether these microalgal proteins exhibit similar properties to proteins from the following legumes: soybeans, lentils, chickpeas, and peas. The focus was on …

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Studies on the Oxidative Damage of the Wobble 5-Methylcarboxymethyl-2-Thiouridine in the tRNA of Eukaryotic Cells with Disturbed Homeostasis of the Antioxidant System

Małgorzata Sierant, Rafał Szewczyk, Agnieszka Dziergowska, Karolina Królewska‐Golińska et autres

We have previously shown that 2-thiouridine (S2U), either as a single nucleoside or as an element of RNA chain, is effectively desulfurized under applied in vitro oxidative conditions. The chemically induced desulfuration of S2U resulted in two products: 4-pyrimidinone nucleoside (H2U) and …

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Studies on Oxidative Damage of the Wobble 5-methylcarboxymethyl-2-thiouridine in tRNA of Eukaryotic Cells with Disturbed Homeostasis of the Antioxidant System

Małgorzata Sierant, Rafał Szewczyk, Agnieszka Dziergowska, Karolina Królewska‐Golińska et autres

We have previously shown that 2-thiouridine (S2U), either as a single nucleoside or as an element of RNA chain, is effectively desulfurized under applied in vitro oxidative conditions. Chemically induced desulfuration of S2U resulted in two products: 4-pyrimidinone nucleoside (H2U) and uridine …

HR-MS/MS is employed to prevent false-positive quantification of 27 psychoactive compounds in venous and VAMS-collected blood samples

Julia Mironenka, M. Stopa, A. Lenartowicz, Rafał Szewczyk et autres

Targeted metabolomics analysis of serum and Mycobacterium tuberculosis antigen-stimulated blood cultures of pediatric patients with active and latent tuberculosis

Magdalena Druszczyńska, Michał T. Seweryn, Sieczkowska Marta, Kowalewska-Pietrzak Magdalena et autres

Profound tuberculosis (TB)-induced metabolic changes reflected in the blood metabolomic profile may provide an opportunity to identify specific markers of Mycobacterium tuberculosis infection. Using targeted liquid chromatography tandem mass spectrometry, we compared the levels of 30 small metabolites, including amino acids and …

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Metabolomic analysis of Trichophyton rubrum and Microsporum canis during keratin degradation

Anita Ciesielska, Anna Kawa, Katarzyna Kanarek, Adrian Soboń et autres

Keratin is important and needed for the growth of dermatophytes in the host tissue. In turn, the ability to invade keratinised tissues is defined as a pivotal virulence attribute of this group of medically important fungi. The host-dermatophyte interaction is accompanied by …

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How Much Emotionally Intelligent AI Can Be?

Rafał Szewczyk, Karolina Janik

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Atrazine biodegradation by mycoinsecticide Metarhizium robertsii: Insights into its amino acids and lipids profile

Rafał Szewczyk, Sylwia Różalska, Julia Mironenka, Przemysław Bernat

Atrazine, is one of major concern pesticides contaminating agricultural areas and ground water. Its microbial biodegradation seems to be the most efficient in terms of economic and environmental benefits. In the present work the cometabolic biodegradation of atrazine by the fungus Metarhizum …

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Wpływ treningu pamięci roboczej na podejmowanie ryzykownych decyzji i wartościowanie odległych nagród w zależności od poziomu obciążenia poznawczego

Rafał Szewczyk