Francesca de

Paper 53. Impact of Osteoarthritis on Outcomes After Implantation of an Aragonite-Based Scaffold for Knee Chondral and Osteochondral Defects: Analysis of an RCT at 5-Year Follow-up

Seth L. Sherman, Kenneth R. Zaslav, Andreas H. Gomoll, Peter Verdonk et autres

Objectives: An aragonite-based, biphasic, acellular scaffold (ABS) has been developed for the treatment knee cartilage lesions. Previously published results from an RCT comparing ABS to surgical standard of care (SSOC, i.e., debridement/microfracture) showed superior clinical outcomes at 24 months post-operatively. The purpose …

Cell‐based therapy injections for the management of knee osteoarthritis: The ESSKA–ICRS consensus. Recommendations using the RAND/UCLA appropriateness method for different clinical scenarios

Laura de Girolamo, Elizaveta Kon, Lior Laver, Luca Andriolo et autres

Abstract Purpose The aim of this consensus was to develop evidence/expert‐based patient‐focused recommendations on the appropriateness of intra‐articular point‐of‐care (POC) cell‐based therapy (CBT) injections in different clinical scenarios of patients with knee osteoarthritis (OA). Methods The RAND/UCLA Appropriateness Method was used by …

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Satisfactory survivorship and clinical outcomes up to 10 years after the implantation of a novel personalized metal implant for the treatment of osteochondral lesions of the knee

Francesca de, Pietro Conte, Kristien Vuylsteke, Chiara Simonini et autres

OBJECTIVES: Treating knee cartilage lesions in middle-aged patients is challenging, particularly when lesions involve the subchondral bone. Personalized focal arthroplasty implants offer a solution when biological repair is no longer optimal or has failed. These small cobalt-chrome implants, designed using patient-specific magnetic …

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Paper 07: Aragonite-Based Scaffold Versus Microfracture and Debridement for the Treatment of Knee Chondral and Osteochondral Lesions: Results of a Multicentre Randomized Controlled Trial at 5 Years Follow-up

Elizaveta Kon, Kenneth R. Zaslav, Seth L. Sherman, Francesca de et autres

Objectives: Articular cartilage lesions are painful and debilitating conditions. A novel aragonite-based scaffold has been developed for the treatment of chondral and osteochondral lesions of the knee. A randomized controlled trial comparing the scaffold to surgical standard of care (SSOC: debridement or …

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Female patients report comparable results to males after the implantation of an aragonite-based scaffold for the treatment of knee chondral and osteochondral defects: a gender-based analysis of a RCT at 4 years’ follow-up

Elizaveta Kon, Francesca de, Vinod Dasa, Jason M. Scopp et autres

BACKGROUND: The aim of the study was to provide a gender-based analysis of the results of a large, multi-centre randomized controlled trial (RCT) comparing a novel cell-free aragonite-based scaffold with the standard of care (i.e. debridement/microfractures) for the treatment of chondral/osteochondral defects …

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The effect of Virtual Reality distraction on discomfort, pain and anxiety during unsedated gastroscopy: a randomized controlled trial

A Bakker-Tijssen, Zita Bouman, Francesca de, M Ruiter De et autres

Aims Gastroscopy is a frequently performed procedure in gastroenterology due to demand of the patients. Many patients prefer sedation though this is a costly procedure due to the need of monitoring the patients during and after sedation. Unsedated gastroscopy is a lot …

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Effects of a Tele-Prehabilitation Program with Indirect Electrostimulation Compared to Home-Based Exercise in Patients Eligible for Lower Limb Arthroplasty: A Randomized Controlled Trial

Pamela Patanè, Vittoria Carnevale Pellino, Massimiliano Febbi, Caterina Cavallo et autres

Background/Objectives: Hip and knee arthroplasty relieves pain, restores mobility, and improves function in severe joint damage, though pain and strength loss may persist post-surgery. Better pre-surgery function and activity predict improved arthroplasty outcomes. Prehabilitation programs enhance functional abilities, reducing hospitalization duration, and …

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Effects of a Tele-Prehabilitation Program with Indirect Electrostimulation Compared to Home-Based Exercise in Patients eligibles for Lower Limb Arthroplasty: A Randomized Controlled Trial

Pamela Patanè, Vittoria Carnevale Pellino, Massimiliano Febbi, Caterina Cavallo et autres

Background/Objectives: Hip and knee arthroplasty relieves pain, restores mobility, and improves function in severe joint damage, though pain and strength loss may persist post-surgery. Better pre-surgery function and activity predict improved arthroplasty outcomes. Prehabilitation programs enhance functional abilities, reducing hospitalization duration, and …

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Malalignment—Varus—High Tibial Osteotomy

Francesca de, Annunziato Amendola

Medial unicompartmental arthritis is frequently encountered in young patients. Degenerative changes of the articular cartilage are more often due to near-total loss of meniscal tissue, ligamentous instability, and malalignment. Alignment of the lower limb has a major influence on the proportion of …

Acellular Aragonite-Based Scaffold for the Treatment of Joint Surface Lesions of the Knee: A Minimum 5-Year Follow-Up Study

Francesca de, Kristien Vuylsteke, Wouter Van Genechten, Peter Verdonk

Objective A novel aragonite-based scaffold has been developed. In this study, mid-term clinical and magnetic resonance imaging (MRI) results on 12 patients affected by isolated chondral or osteochondral lesions of the knee treated by the scaffold implantation have been evaluated at a …

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Lower Limb Arthroplasty: Effects of a Tele-Prehabilitation Program with Indirect Electrostimulation. Feasibility Study

Massimiliano Febbi, Matteo Vandoni, Pamela Patanè, Stefania Ballarin et autres

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Comparative Efficacy of Leg Pneumatic Compression and Antithromboembolic Exercise in Managing Lower Limb Edema After Total Hip Arthroplasty. Feasibility Trial

Vittoria Carnevale Pellino, Alessandro Gatti, Matteo Vandoni, Pamela Patanè et autres

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