Aikou Okamoto

Reconnecting and advancing: East Asian collaboration in obstetrics and gynaecology after the 2025 Tokyo-Beijing-Seoul Joint Meeting

Masataka Takenaka, Masahiko Nakata, Tsutomu Tabata, Jae Kwan Lee et autres

East Asia has long been committed to strengthening international academic ties and joint innovation in the field of medicine. On 7 June 2025, the academic community of East Asia marked a significant milestone with the successful convocation of the Tokyo-Beijing-Seoul (TBS) Joint …

jp, kr, Éthiopie, cn (code pays fourni par la source)

AI-based quantification of tumor-infiltrating lymphocytes with integrative transcriptomics in ovarian clear cell carcinoma: JGOG3025-TR1/A1 study

Kohei Hamada, Junzo Hamanishi, Akihiko Ueda, Shiro Takamatsu et autres

Transcriptomic classification methods have been proposed for ovarian clear cell carcinoma. However, their clinical significance and association with pathologically evaluated tumor-infiltrating lymphocytes (TILs) remain unclear. We established two large transcriptomic datasets and analyzed RNA-sequencing data from 189 (JGOG3025-TR1 cohort) and 38 (Kyoto …

jp (code pays fourni par la source)

Uterine-sparing Robot-assisted Sacrocolpopexy for Pelvic Organ Prolapse in Women Aiming for Pregnancy

Wakiko Shimomai, Hiroe Ito, Jiro Suzuki, Satoshi Yanagida et autres

Pelvic organ prolapse (POP) is frequently encountered in elderly women. However, it can also affect relatively young women of reproductive age. Here, we present three cases of uterine-sparing robot-assisted sacrocolpopexy (RSC) in women aiming for pregnancy. All cases were diagnosed with POP-Q …

jp (code pays fourni par la source)

AVUTOMETINIB + DEFACTINIB IN RECURRENT LOW-GRADE SEROUS OVARIAN CANCER (LGSOC): A PHASE 2 STUDY IN JAPANESE PATIENTS

Takafumi Kuroda, Muneaki Shimada, Michiko Kaneda, Shin Nishio et autres

jp, us (code pays fourni par la source)

Clinical outcomes and prognostic factors of adjuvant radiotherapy for vulvar cancer: a Japanese Gynecologic Oncology Group nationwide survey study

Keisuke Tsuchida, Ken Ando, Noriyuki Okonogi, Mayuyo Mori et autres

This study aimed to analyze the clinical outcomes and prognostic factors of postoperative adjuvant radiotherapy (RT) for vulvar cancer based on a retrospective Japanese nationwide survey. Data were collected from 108 institutions for patients diagnosed with vulvar cancer between January 2001 and …

jp (code pays fourni par la source)

Maternal and neonatal outcomes in full-term pregnancies of very advanced maternal age: a Japanese single-center retrospective cohort study

Rintaro Hamada, Akihiro Hasegawa, Yuto Maeda, Tokumasa Suemitsu et autres

BACKGROUND: Advanced maternal age (AMA), defined as pregnancy in people aged ≥ 35 years, is associated with an increased risk of adverse perinatal outcomes. Although the outcomes of AMA pregnancies have been reported, detailed information on the specific outcomes in pregnant individuals …

jp (code pays fourni par la source)

Veliparib concomitant with first-line chemotherapy and as maintenance therapy in ovarian cancer: Final overall survival and disease-related symptoms results

Robert L. Coleman, Gini F. Fleming, Mark F. Brady, Elizabeth M. Swisher et autres

us, dk, au, jp (code pays fourni par la source)

Impact of germline variants on breast and ovarian cancer risk in Japanese women: an original cohort study and meta-analysis

Shu Yazaki, Megumi Hori, Hisaki Aiba, Yukihide Momozawa et autres

BACKGROUND: Pathogenic variants (PVs) of BRCA1 and BRCA2 predispose individuals to a higher risk of breast and ovarian cancer; however, the precise risks posed by other cancer susceptibility genes remain unclear, particularly in Asian populations. METHODS: We executed a case-control study of …

us, gb, jp (code pays fourni par la source)

Low-dose ferric carboxymaltose vs. oral iron for improving hemoglobin levels in postpartum East Asian women: A randomized controlled trial

Takeshi Nagao, Ken Takahashi, Sho Takahashi, Ryo Yokomizo et autres

Ferric carboxymaltose (FCM) is widely used to correct anemia and replenish iron stores rapidly, particularly in Western populations. However, lower doses of FCM are typically used in East Asia, with limited research on their effectiveness, especially in postpartum women. This randomized controlled …

jp (code pays fourni par la source)

PR025/#326 Validity of CA-125 elimination rate constant K for indicating prognosis and therapeutic selection among Japanese patients with high-grade serous ovarian carcinoma: a single-center retrospective study

Yuki Kochi, Daito Noguchi, Satoshi Hosoya, Junya Tabata et autres

Analysis of susceptibility to ferroptosis via functional analysis of macro-bleb in trophoblast

Kazuhiro Kajiwara, K Ozawa, Osamu Samura, Beharier Ofer et autres

jp, us (code pays fourni par la source)

Assessment of postoperative therapy de-escalation for early-stage, intermediate-risk cervical cancer

Koji Matsuo, Muneaki Shimada, Shinya Matsuzaki, Hiroko Machida et autres

us, jp (code pays fourni par la source)