Nanoparticles containing β‐cyclodextrin potentially useful for the treatment of Niemann‐Pick C
Bruna Donida, Marco Raabe, Bárbara Tauffner, Marcelo Alexandre de Farias et autres
β-Cyclodextrin (β-CD) is being considered a promising therapy for Niemann-Pick C (NPC) disease because of its ability to mobilise the entrapped cholesterol from lysosomes, however, a major limitation is its inability to cross the blood-brain barrier (BBB) and address the central nervous …
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