Haofuzi Zhang

What Reconstructing a Smile Taught Me About Being a Surgeon

Haofuzi Zhang, Maoguo Shu

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Mendelian randomization study of genetic interactions between Alzheimer disease and celiac disease

Zhong Yu, Lu Hao, Haofuzi Zhang

Epidemiological evidence suggests an association between celiac disease (CeD) and Alzheimer disease (AD). However, the association between CeD and AD remains debated. Therefore, this study aims to explore the causal association between CeD and AD. This study utilized publicly available genome-wide association …

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Advances in genetic mechanisms and precision medicine research for cleft lip and palate

Zhong Yu, Chenhui Feng, Tianhua Li, Han Duan et autres

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Importance of clinical trials and contributions to contemporary medicine: commentary

Haofuzi Zhang, Xiaofan Jiang

Clinical trials are crucial to contemporary medicine, offering valuable insights into the safety, efficacy, and appropriate use of new treatments. They contribute to public health improvements, reduce healthcare costs, uncover new understandings of disease biology, and facilitate the development of therapies for …

Importance of clinical trials and contributions to contemporary medicine: commentary

Haofuzi Zhang, Xiaofan Jiang

Clinical trials are crucial to contemporary medicine, offering valuable insights into the safety, efficacy, and appropriate use of new treatments. They contribute to public health improvements, reduce healthcare costs, uncover new understandings of disease biology, and facilitate the development of therapies for …

High-altitude hypoxia aggravated neurological deficits in mice induced by traumatic brain injury via BACH1 mediating astrocytic ferroptosis

Peng Zou, Tianjing Li, Zixuan Cao, Erwan Yang et autres

Traumatic brain injury (TBI) is one of the leading causes of disability and mortality, which was classified as low-altitude TBI and high-altitude TBI. A large amount of literature shows that high-altitude TBI is associated with more severe neurological impairments and higher mortality …

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Machine Learning for the Early Prediction of Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage: Systematic Review and Meta-Analysis

Haofuzi Zhang, Peng Zou, Peng Luo, Xiaofan Jiang

BACKGROUND: Delayed cerebral ischemia (DCI) is a primary contributor to death after subarachnoid hemorrhage (SAH), with significant incidence. Therefore, early determination of the risk of DCI is an urgent need. Machine learning (ML) has received much attention in clinical practice. Recently, some …

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Brain with coexistent acoustic schwannoma and ependymoma

Haofuzi Zhang, Peng Zou, Lin Wei, Xiaofan Jiang

BACKGROUND: This particular case is a world-first with no previous literature reports on patients presenting with both benign acoustic schwannoma and malignant ependymoma. CASE PRESENTATION: A 60-year-old woman with unexplained right-sided hearing loss that had worsened progressively over 4 years, along with …

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Importance of clinical trials and contributions to contemporary medicine: commentary

Haofuzi Zhang, Xiaofan Jiang

Clinical trials are crucial to contemporary medicine, offering valuable insights into the safety, efficacy, and appropriate use of new treatments. They contribute to public health improvements, reduce healthcare costs, uncover new understandings of disease biology, and facilitate the development of therapies for …

cn (code pays fourni par la source)

Nomogram and randomized survival forest model for predicting sepsis risk in patients with cerebral infarction in the intensive care unit

Haofuzi Zhang, Kangyi Yue, Yutong Wang, Hao Lü et autres

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Analysis of surgical treatment of cervical spondylotic amyotrophy

Yu Zhong, Haofuzi Zhang, Yanjun Wang

Background: Cervical spondylotic amyotrophy (CSA) is a special type of cervical spondylosis based on cervical degeneration, which is mainly manifested by weakness and atrophy of upper limb muscles without obvious sensory impairment. Various diagnostic and treatment strategies used; however, discrepancies exist. We …

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Preso enhances mGluR1-mediated excitotoxicity by modulating the phosphorylation of mGluR1-Homer1 complex and facilitating an ER stress after traumatic brain injury

Zhuoyuan Zhang, Xiangyu Gao, Zhicheng Tian, Erwan Yang et autres

Abstract Glutamate receptor (GluR)-mediated excitotoxicity is an important mechanism causing delayed neuronal injury after traumatic brain injury (TBI). Preso, as a core scaffolding protein of postsynaptic density (PSD), is considered an important regulator during excitotoxicity and TBI and combines with glutamate receptors …

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