C Sheela Devi

Multicenter epidemiology of Stenotrophomonas maltophilia bloodstream infections in Indian ICUs: building digital surveillance network

Parul Singh, M. Nizam Ahmed, Ashish Kumar Srivastava, Arpan Kumar Thakur et autres

Background To investigate the geospatial epidemiology, clinical features, treatment patterns, and antimicrobial resistance (AMR) trends of Stenotrophomonas maltophilia bloodstream infections (BSIs) in Indian intensive care units (ICUs) participating in a standardized healthcare-associated infection (HAI) surveillance program from 2017 to 2024. Methods This …

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Epidemiology of non-central line-associated primary bloodstream infections in a network of Indian hospitals: A prospective surveillance study over 7 years (2017-2024)

Ashish Kumar Srivastava, Arpan Kumar Thakur, Kumari Vandana Singh, Rasna Parveen et autres

OBJECTIVES: To estimate the profile of non-central line-associated primary bloodstream infections (non-CLABSIs) in intensive care units of Indian hospitals participating in the standardized health-care-associated infection surveillance program. METHODS: This is a multicentric, network-based, prospective surveillance study conducted in 180 individual intensive care …

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Screening for mutations in pmrB gene to predict potential colistin resistance among the clinical isolates of multidrug-resistant Acinetobacter baumannii

Sridevi Dinakaran, Ajit Ramesh Sawant, C Sheela Devi, Reba Kanungo

PURPOSE: Infections caused by multidrug-resistant Acinetobacter baumannii (MDR-AB) are a major global problem. Increasing resistance to carbapenems among Acinetobacter baumannii (A.baumannii) has led to using colistin as a last resort. Overuse of colistin will lead to the emergence of colistin resistance as …

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Vancomycin and linezolid creeping minimum inhibitory concentrations in clinical isolates of MRSA: Prelude to overt resistance

Sandhya Bhat, Desdemona Rasitha, Kandasamy Ravichandran, C Sheela Devi et autres

Vancomycin and linezolid creeping minimum inhibitory concentrations in clinical isolates of MRSA: Prelude to overt resistance - IJMR- Print ISSN No: - 2394-546X Online ISSN No:- 2394-5478 Article DOI No:- 10.18231/j.ijmr.2025.038, Indian Journal of Microbiology Research-Indian J Microbiol Res

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In-vitro Evaluation of Synergy Testing of Ceftazidime-Avibactam-Aztreonam among Carbapenem-Resistant Gram-Negative Organisms

Sridevi Dinakaran, C Sheela Devi, Sandhya Bhat

The prevalence of severe infections due to Carbapenemase –resistant Enterobacterales (CRE) and Pseudomonas aeruginosa (CR-PA) has increased worldwide. The treatment has become challenging and limited among the metallo-β-lactamases (MBLs) producing organisms due to the rise in polymyxin resistance. Due to the paucity …

Clinico-microbiological profile of Burkholderia pseudomallei infections in a tertiary care hospital in South India

Priya Ramachandran, K. Sandhya Bhat, C Sheela Devi

Melioidosis, caused by Burkholderia pseudomallei, is known for its diverse clinical presentations and high mortality rate. This brief communication reports the clinico-microbiological profile of twenty cases of melioidosis in a tertiary care hospital over three years. We have analyzed demographic data, clinical …

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Outcome of hand hygiene audit in intensive care unit during COVID-19: An experience from a tertiary care centre

E. Arthi, V. Sujitha, J. Vidya, A. Shobana et autres

Background: Hand hygiene (HH) remains a simple, cost-effective method to prevent healthcare-associated infections. Although the recent COVID-19 pandemic has brought out the importance of HH, its compliance remains below the set standards. Hence, monitoring HH compliance in hospital setup through audits remains …

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Detection of 16S rRNA gene for rapid identification of bacterial pathogens causing peritonitis in patients on continuous ambulatory peritoneal dialysis

C Sheela Devi, P. Vivian Joseph Ratnam, S R Ramya, Reba Kanungo et autres

PURPOSE: Peritonitis is the most important complication with high rate of morbidity and mortality in patients on continuous ambulatory peritoneal dialysis (CAPD) despite the success and advances. Rapid and accurate identification of pathogens causing peritonitis in a CAPD patient is essential for …

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Risk factors, bacteriological profile and outcome of surgical site infections following orthopaedic surgery

Shishir Murugharaj Suranigi, S R Ramya, C Sheela Devi, Reba Kanungo et autres

Background and Objectives: Surgical site infection (SSI) is a challenge for the surgeon. Incidence of SSI reported in literature varies from 0.5% to 15%. Severity of SSI ranges from superficial skin infection to life-threatening condition like septicaemia. It is responsible for increased …

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Detection of bacterial DNA in infected body fluids using 16S rRNA gene sequencing: Evaluation as a rapid diagnostic tool

S R Ramya, C Sheela Devi, Anand Babu Perumal, Johny G Asir et autres

CONTEXT: Rapid detection of pathogens in infected body fluids will help in establishing an aetiological diagnosis, thereby facilitating specific therapy. Molecular methods have an advantage over conventional bacteriological techniques in particularly identifying slow-growing, fastidious or non-cultivable organisms.AIM: The aim of this study …

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Simple and economical method for identification and speciation of Staphylococcus epidermidis and other coagulase negative Staphylococci and its validation by molecular methods

Suresh Sah, Priyanka Bordoloi, D Vijaya, S. Amarnath et autres

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Emergence of carbapenem non‐susceptible multidrug resistant Acinetobacter baumannii strains of clonal complexes 103B and 92B harboring OXA‐type carbapenemases and metallo‐β‐lactamases in Southern India

Rajagopalan Saranathan, Vasanth Vaidyanathan, Thamodharan Vasanth, Pidathala Raghavendra Venkata Shabareesh et autres

The molecular epidemiology and carbapenem resistance mechanisms of clinical isolates of Acinetobacter baumannii obtained from a south Indian tertiary care hospital were investigated by repetitive extragenic palindromic sequence PCR (REP-PCR) and multi-locus sequence typing (MLST). Analysis of resistant determinants was achieved by …

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