Luciano Calderone

Remimazolam in Endoscopy: A Game-Changer for Safe and Effective Sedation in Real-World Practice

Alba Sparacino, P. Graceffa, I A Salerno, Fabio Cartabellotta et autres

Aims This study aimed to evaluate the efficacy and safety of remimazolam as a sedative agent for procedural sedation-analgesia (PSA) in upper and lower gastrointestinal (GI) endoscopy Methods A prospective, multicenter, real-world study was conducted between November 2024 and January 2025. Ninety-seven …

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The use of pilocarpine in opioid-induced xerostomia

Sebastiano Mercadante, Luciano Calderone, Paolo Villari, Roberto Serretta et autres

Oral dryness can be a symptom of asystemic disease, an adverse effect of anticholin-ergic, antiadrenergic or cytotoxic drug treatment, orit can be due to local radiotherapy. Opioid use isstrongly associated with xerostomia, although themechanism for this remains unclear; in one studypatients receiving …

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Rapid Switching From Morphine to Methadone in Cancer Patients With Poor Response to Morphine

Sebastiano Mercadante, Alessandra Casuccio, Luciano Calderone

PURPOSE: The aim of this study was to evidence the clinical effects of an abrupt substitution of morphine with methadone using a fixed ratio of 1:5 in patients for whom limiting adverse effects occurred before adequate analgesia was achieved with oral morphine. …

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When all else fails: stepwise multiple solutions for a complex cancer pain syndrome

Sebastiano Mercadante, Roberto Serretta, Monica Sapio, Paolo Villari et autres

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Rapid S witching F rom M orphine t o M ethadone i n C ancer Patients W ith P oor R esponse t o M orphine

Sebastiano Mercadante, Alessandra Casuccio, Luciano Calderone

Purpose: The aim of this study was to evidence the clinical effects of an abrupt substitution of morphine with methadone using a fixed ratio of 1:5 in patients for whom limiting adverse effects occurred before adequate analgesia was achieved with oral morphine. …

Correspondence

Sebastiano Mercadante, Luciano Calderone, Roberto Serretta, R Salvina

Morphine versus methadone in the pain treatment of advanced-cancer patients followed up at home.

Sebastiano Mercadante, Alessandra Casuccio, Antonio Agnello, Roberto Serretta et autres

PURPOSE: The aim of this study was to evaluate the analgesic and adverse effects and the doses of methadone in comparison to morphine. PATIENTS AND METHODS: A prospective randomized study was performed in a sample of 40 patients with advanced cancer who …

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Intrathecal Ropivacaine in Cancer Pain

Sebastiano Mercadante, Luciano Calderone, Luca Barresi

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A.337 Comfort sedation by clonidine during Intrathecal anaesthesia for cesarean section

Sebastiano Mercadante, Luciano Calderone, Monica Sapio, R. Serretta et autres

A.404 Monitoring of opioid responsiveness in cancer pain

Sebastiano Mercadante, Monica Sapio, Paolo Villari, Luciano Calderone et autres