Raquel Arinto-Garcia

Streamlined purification of ADDomer nanoparticles for scalable biomanufacturing

Raquel Arinto-Garcia, Cláudia S. Paiva, Emerson Bryan Dilla, Dirk E. Martens et autres

Current lab-scale purification methods for ADDomer are labour-intensive, time-consuming and poorly scalable. The intracellular nature of ADDomer production further complicates downstream processing, requiring robust, scalable solutions for cell lysis and clarification. In the present work we focus on developing a scalable, GMP-compliant …

pt, nl, us, gb (code pays fourni par la source)

ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming

Stefanie K. Menzies, Raquel Arinto-Garcia, Fernanda Gobbi Amorim, Iara Aimê Cardoso et autres

Snakebite envenoming can be a life-threatening medical emergency that requires prompt medical intervention to neutralise the effects of venom toxins. Each year up to 138,000 people die from snakebites and threefold more victims suffer life-altering disabilities. The current treatment of snakebite relies …

gb, pt, be, fr (code pays fourni par la source)

ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming

Stefanie K. Menzies, Raquel Arinto-Garcia, Fernanda Gobbi Amorim, Iara Aimê Cardoso et autres

Snakebite envenoming can be a life-threatening medical emergency that requires prompt medical intervention to neutralise the effects of venom toxins. Each year up to 138,000 people die from snakebite and 3-fold more victims suffer life-altering disabilities. Current treatment of snakebite relies solely …

Optimizing Recombinant Baculovirus Vector Design for Protein Production in Insect Cells

Carina Bannach, Daniel Ruiz Buck, Genna Bobby, Leo P. Graves et autres

Autographa californica nucleopolyhedrovirus is a very productive expression vector for recombinant proteins in insect cells. Most vectors are based on the polyhedrin gene promoter, which comprises a TAAG transcription initiation motif flanked by 20 base pairs upstream and 47 base pairs downstream …

gb, cn (code pays fourni par la source)

Optimising recombinant baculovirus vector design for protein production in insect cells

Carina Bannach, Daniel Ruiz Buck, Genna Bobby, Leo P. Graves et autres

Autographa californica nucleopolyhedrovirus is a very productive expression vector for recombinant proteins in insect cells. Most vectors are based on the polyhedrin gene promoter, which comprises a TAAG transcription initiation motif flanked by 20 base pairs upstream and 47 base pairs downstream …

gb (code pays fourni par la source)

Comparing Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry and Phenotypic and Molecular Methods for Identification of Species within the Streptococcus anginosus Group

Raquel Arinto-Garcia, Marcos D. Pinho, João André Carriço, José Melo‐Cristino et autres

The heterogeneity of members of the Streptococcus anginosus group (SAG) has traditionally hampered their correct identification. Recently, the group was subdivided into 6 taxa whose prevalence among human infections is poorly described. We evaluated the accuracy of the Rapid ID32 Strep test, …

pt (code pays fourni par la source)

Multilocus sequence analysis of Streptococcus anginosus group

Raquel Arinto-Garcia, Marcos D. Pinho, João André Carriço, José Melo‐Cristino et autres

This fileset contains individual FASTA files for the unique alleles at each of the loci considered in the Multilocus Sequence Analysis method used and two supplementary tables with the information of individual strains.

Multilocus sequence analysis of Streptococcus anginosus group

Raquel Arinto-Garcia, Marcos D. Pinho, João André Carriço, José Melo‐Cristino et autres

This fileset contains individual FASTA files for the unique alleles at each of the loci considered in the Multilocus Sequence Analysis method used and two supplementary tables with the information of individual strains.