George Aggelis

Metabolic Responses of Newly Isolated Microalgal Strains Cultured in an Open Pond Simulating Reactor Under Balanced Conditions and Nutrient Limitation

Panagiotis Dritsas, George Aggelis

PAT2.7-were evaluated in an Open Pond Simulating Reactor (OPSR) under varied conditions to assess their biomass yield and high-value metabolite production. Overall, the strains produced 269.1-523.0 mg/L of biomass under balanced growth conditions in modified Artificial Seawater, continuous illumination, and pH 8.5. …

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Renewable carbon sources as microbial substrates for the production of amylases and lignocellulases

Panagiota A. Diamantopoulou, George Aggelis, Seraphim Papanikolaou

In the present review-article several aspects dealing with the biotechnological production of two major groups of enzymes, viz . amylases and lignocellulases, are discussed. The chemical composition and structure of the substrates ( viz . starch and related compounds and lignocellulose) on …

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Investigating the Potential of Newly Isolated Microalgae Strains from the Ionian Sea (Greece) Cultured in an Open Raceway Pond

Panagiotis Dritsas, Stefania Patsialou, Dimitrios Kampantais, Efstratios Roussos et autres

Microalgae are a subject of interest not only for fundamental research but for various biotechnological applications as well. In this study, the ability of newly isolated strains, i.e., Picochlorum costavermella VAS2.5, Picochlorum oklahomense SAG4.4, Microchloropsis gaditana VON5.3, and Nephroselmis pyriformis PAT2.7, to …

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Pomegranate residues as fermentation feedstock for bioethanol production: Process design and characterization

Anastasios Kyriazis, George Aggelis, Alexandra Lianou

Pomegranate residues (PRs), namely pomegranate peels and seeds remaining after juice extraction, constitute a significant agro-industrial residue in Greece. Despite their ample content in carbon sources and bioactive compounds, PRs are largely unexploited, with their management being an increasing concern for the …

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Impact of Temperature on the Biochemical Potential of Five Newly Isolated Strains of Microalgae Cultured in a Stirred Tank Reactor

Panagiotis Dritsas, George Aggelis

The microalgal strains Picochlorum costavermella VAS2.5, Picochlorum oklahomense SAG4.4, Picochlorum oklahomense PAT3.2B, Microchloropsis gaditana VON5.3, and Nephroselmis pyriformis PAT2.7 were cultured in a Stirred Tank Reactor at 25 °C or 20 °C in modified artificial seawater and their biotechnological potential was assessed. …

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Isolation and characterization of phenolic substances from pomegranate residues

Costas S. Papageorgiou, Anastasios Kyriazis, Andreas D. Zentelis, Vassilis A Ioannidis et autres

Abstract BACKGROUND Pomegranate Residues (PRs) can be utilized for the development of a fermentation substrate for bioethanol production, while the contained bioactive substances could be recovered with physicochemical separation processes to be used in pharmaceutics or cosmetic products. Herein, we focused on …

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First generation vanadium-based PTEN inhibitors: Comparative study in vitro and in vivo and identification of a novel mechanism of action

Kyriaki Premeti, Dimitra Tsipa, Antonios E Nadalis, Michael G. Papanikolaou et autres

values between 0.2-0.8 μM, although their activity diminished under reducing conditions. bpV(phen) and bpV(HΟpic) significantly increased pSer473Akt levels in PTEN wild-type cells while bpV(phen) induced phosphorylation in PTEN null cells upon re-expression of functional PTEN. bpV(ΗΟpic) was less specific since it also …

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Impact of Temperature on the Biochemical Potential of Five Newly-Isolated Strains of Microalgae Cultured in a Stirred-Tank Reactor

Panagiotis Dritsas, George Aggelis

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Molecular and biochemical characterization of cyanobacterial strains isolated from the Ionian Sea (Greece)

Panagiotis Dritsas, Elias D. Asimakis, Alexandra Lianou, Maria Efstratiou et autres

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Polyunsaturated Fatty Acids from Thamnidium elegans and Mortierella alpina Suppress Prostate Cancer Cell Proliferation and Migration

Georgios Kalampounias, Panagiotis Dritsas, Dimitris Karayannis, Theodosia Androutsopoulou et autres

Thamnidium elegans and Mortierella alpina are two oleaginous fungi that belong to Mucoromycota that synthesize polyunsaturated fatty acids, which are credited with multiple health benefits and possible anticancer properties. These fungi were cultivated on culture media, with glucose or glycerol as a …

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Fermentative and Enological Features of Saccharomyces cerevisiae Populations Generated Through Adaptive Laboratory Evolution

Maria Mavrommati, Stefania Christofi, Stamatina Kallithraka, Séraphim Papanikolaou et autres

Adaptive laboratory evolution (ALE) is a non-GMO technique utilized for the amelioration of wine yeast strains. Employing two-step ALE strategies, we recently acquired six evolved Saccharomyces cerevisiae populations with improved fermentative abilities compared to their parental strains in synthetic broths. Herein, we …

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Simultaneous improvement of fructophilicity and ethanol tolerance of Saccharomyces cerevisiae strains through a single Adaptive Laboratory Evolution Strategy

Maria Mavrommati, Christina Ν. Economou, Stamatina Kallithraka, Séraphim Papanikolaou et autres

Saccharomyces cerevisiae is the main yeast used in the winemaking industry. Its innate glucophilicity provokes a discrepancy in glucose and fructose consumption during alcoholic fermentation of grape must, which, combined with the inhibitory effect of ethanol accumulated in the fermentation broth, might …

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