Dan He

Association of glucagon-like peptide-1 receptor agonists with atrial fibrillation recurrence after catheter ablation: a systematic review and meta-analysis

Dan He, Defu Lv, Jiaxin Tang, Xiaojuan Liao et autres

Background Current studies suggest a potential association between the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and atrial fibrillation (AF) recurrence after catheter ablation, but the findings remain controversial. Therefore, we conducted a meta-analysis to evaluate this association, aiming to provide evidence …

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The Words of Proteins: Motif-Level Language Modeling for Interpretable Protein Generation

Boon How Low, Wen Yang Goh, Boyang Li, Dan He

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Redox-activated chemistry for probing and perturbing the proteome: Lessons from protein redox switches

Qiyue Zeng, Jingcheng Yang, Dan He

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Novel drug-drug cocrystal form of Luteolin with Metformin: Improved solubility, bioavailability, and in vitro anticancer activity

Jianing Zhao, Yiwu Wang, Xuanheng Chen, Yue Wu et autres

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Efficient photodynamic and photocatalytic anticancer activity of a Ru(II) polypyridyl complex

Qiang Tang, L.‐J. CHEN, Dan He, Yue Wu et autres

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RAD23B acquires a copper metalloadaptor function in amphibian-to-reptile evolution to increase metabolism and regulate genomic integrity

Tong Xiao, Dan He, Danqian Liu, Shang Jia et autres

Increasing brain complexity is a major step in the evolution of species. Here, we show that, in the transition from amphibians to reptiles, the DNA repair protein RAD23B acquires a metalloadaptor function that allows it to serve as a central hub for …

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Fluorine‐ and Trifluoromethyl‐Substituted Biphenyl Derivatives: Promising Antimicrobial Agents Targeting Escherichia coli FabH

Qike Jia, Zhiyu Zhu, Ruiying Ji, Feifan Yang et autres

ABSTRACT This study investigates the synthesis, antibacterial activity, structure–activity relationships (SARs), and molecular docking of F‐ and CF 3 ‐substituted biphenyl derivatives ( 5A – 5K ) as potential antimicrobial agents. Ten novel biphenyl derivatives were synthesized, incorporating trifluoromethyl (CF 3 ) …

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Integrated bioinformatics analysis identifies CHAD association with osteoporosis and in vitro chondrogenic effects of Wogonin

Keng‐Fu Lan, Wei-Nien Joe Su, Yan Wu, Siqi Ye et autres

Osteoporosis (OP), characterized by reduced bone density and increased fracture risk. Current therapies have limitations due to side effects and variable efficacy, necessitating exploration of novel therapeutic targets and alternatives like Traditional Chinese Medicine (TCM). The molecular mechanisms driving OP remain incompletely …

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Biosynthesis of 10-Hydroxy-2-Decenoic Acid in Escherichia coli

Dan He, Yan Chen, Junfeng Shen, Yu Han et autres

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Author Correction: Oxidative cyclization reagents reveal tryptophan cation–π interactions

Xiao Xie, Patrick J. Moon, Steven W. M. Crossley, Amanda J. Bischoff et autres

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The Evolution of Government's Public Service Purchase Policy: A Historical Institutionalism Framework of Analysis

Dan He, Zhayang Zhaoma

Public service innovation is the eternal theme of government management. Scientifically recognizing the change process, evolution logic and dynamic mechanism of the government's public service purchase policy is not only an important support for grasping the policy direction and optimizing the policy …

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Potential involvement of connective tissue growth factor in chondrocytes apoptosis of Kashin-Beck disease

Xuena Yang, Huan Liu, Shiqiang Cheng, Chuyu Pan et autres

BACKGROUND: Kashin-Beck disease (KBD) is an endemic osteoarthropathy characterized by excessive chondrocytes apoptosis. T-2 toxin exposure has been proved to be its etiology. Connective tissue growth factor (CTGF) exerts a profound influence on cartilage growth and metabolism. We investigated the potential role …

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