Uli Schwab

47 The first UK clinical case series of BCGosis: a retrospective review in a tertiary centre

Chung Mun Alice Lin, Sujoy Biswas, Jim Macfarlane, Bijan Ghavami-Kia et autres

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Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study

Douglas Fink, W.J.G. Beynon, Jospeh Heskin, Lara Payne et autres

Background The scale of the 2022 global mpox (formerly known as monkeypox) outbreak has been unprecedented. In less than 6 months, non-endemic countries have reported more than 67 000 cases of a disease that had previously been rare outside of Africa. Mortality …

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Clinical features and management of human monkeypox: a retrospective observational study in the UK

Hugh Adler, Susan Gould, Paul Hine, Luke B. Snell et autres

BACKGROUND: Cases of human monkeypox are rarely seen outside of west and central Africa. There are few data regarding viral kinetics or the duration of viral shedding and no licensed treatments. Two oral drugs, brincidofovir and tecovirimat, have been approved for treatment …

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North by Northeast - a case of CNS Aspergilloma mistaken for pituitary tumour

Vino Srirathan, Uli Schwab

Background Fungal pituitary sellar infection is a rare condition and can resemble a pituitary tumour. Our patient required two debridements across two continents. Case A 47-year-old diabetic man presented with history of headaches and sudden visual loss, on neuroimaging found to have …

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Gram-negative Galore and the Gut

Shobana Anpalakhan, Uli Schwab

An 81-year-old diabetic man with PAF, pleural thickening due to benign fibrous pleuritis and a PPM developed rigors/pyrexia (39°C) with no localising signs of infection. Blood cultures grew Pseudomonas aeruginosa (May 2017) and Enterococcus faecalis (November 2017), MSU was negative and imaging …

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Antibiotics & adjuvant corticosteroids in management of pneumococcal meningitis: a retrospective case-notes audit

Andrew Barr, Uli Schwab

Background Pneumococcus remains the most common cause of bacterial meningitis with high morbidity and mortality. Adjuvant corticosteroids with early antibiotics have been shown to reduce the neurological morbidity and mortality respectively and this is reflected in British Infection Society (BIS) guidance. Aim …

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Snorting Staphylococcus Aureus

Amy Belfield, Uli Schwab

Rates of cocaine use in the UK remain high and Physicians need to be familiar with pleuropulmonary complications associated with illicit use. Respiratory symptoms (e.g cough productive of carbonaceous material/chest pain/dyspnoea/haemoptysis/wheeze) are quite common after cocaine exposure and can lead to barotrauma/asthma/ischaemic-airways-necrosis/pneumonia/interstitial-lung-disease/pulmonary-hypertension, …

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Audit to assess adequacy of Screening of latent TB in Newly diagnosed HIV patients

Clare Bristow, Uli Schwab

Introduction Patients with Human Immunodeficiency Virus (HIV) are at an increased risk of latent Tuberculosis (TB) reactivation. HIV TB concurrent infection increases mortality and reduces patient quality of life. Screening for latent TB allows treatment to commence, preventing reactivation. In accordance with …

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Hubris Haemoptysis - Mycobacterium kansasii , are you taking the piss?

Francesca Peters, Uli Schwab

Background: A 33 year old HIV-negative Gambian, who hadn’t left the UK for 7 years, presents with haemoptysis, 6 month cough, sweats, and weight loss. He completed standard treatment for presumed pulmonary TB in Banjul (2006), with a completely normal CXR (2015). …

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A Paradoxical Puzzle: Delayed reaction during treatment for disseminated BCG

Shobana Anpalakhan, Uli Schwab

A 74-year-old man with no previous history of tuberculosis presented with malaise, pyrexia (39°C) and 35kg weight loss, 16 months after TURBT for transitional cell carcinoma of the bladder and BCG instillation. He was pancytopaenic (Hb 84, Plt 99, WCC 2.94) and …

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Easy to get, but not always easy to treat - Clinical and serological failure with Azithromycin in Syphilis: Time to adapt national guidelines?

Daisy Ogbonmwan, Uli Schwab

Background Data since 2014 has shown a rise in the incidence of Syphilis especially amongst heterosexuals. In national guidelines, Macrolides remain an alternative treatment option although their efficacy has been long disputed. We describe a case of a patient with clinical and …

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Analysis of outpatient and home parenteral intravenous antibiotic therapy (OHPAT) cases at the Newcastle upon Tyne Hospitals NHS Foundation Trust from April 2017 to June 2019

Joshua Pinedo, Uli Schwab

Introduction and Methods Newcastle’s OHPAT service has been operating since 2011, providing intravenous antimicrobials on outpatient basis for deep seated infections (DSI) and skin and soft tissue infections (SSTI); either provided at the OHPAT service in hospital (H-OPAT), delivered to the patient’s …

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