Mir Shanaz Hossain

Mastectomy pain blocks: A comparison of preoperative versus intraoperative pectoralis nerve blocks

Priya S. Bhakta, Sabry Ayad, Mir Shanaz Hossain, Nicholette Black et autres

BACKGROUND: Pectoralis nerve blocks (PNB) are increasingly used for post-mastectomy analgesia. We evaluated whether block timing (preoperative vs intraoperative) affected postoperative opioid use. METHODS: A retrospective review of mastectomy patients receiving preoperative (PPNB) or intraoperative (IPNB) PNB was performed. Multivariable analysis assessed …

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Recent Advances in Therapeutic Approaches for Knee Osteoarthritis: a Narrative Review

Mir Shanaz Hossain, Hyun Jae Lee, Rajib Hossain, C. C. Kim et autres

Knee osteoarthritis (KOA) is a progressive and chronic musculoskeletal condition that continues to be the leading cause of disability worldwide. Conventional treatment approaches for the management of KOA largely focus on symptom alleviation rather than halting or reversing disease progression. However, recent …

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A two-center study of laparoscopic appendectomy for chronic abdominal pain

Cecilia Gigena Heitsman, Mir Shanaz Hossain, Alison K. Heilbronner, Akua F. A. Abrah et autres

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Taxifolin Regulates the Gene Expression of MUC5AC Mucin via Affecting IκBα/NF-κB p65 Signaling in Human Airway Epithelial Cells

Rajib Hossain, Mir Shanaz Hossain, Hyun Jae Lee, Choong Jae Lee

In this study, we explored the effects of taxifolin, a flavonoid compound, on the expression of the MUC5AC mucin gene in airway epithelial cells. Human pulmonary epithelial NCI-H292 cells were pretreated with taxifolin for 30 min prior to stimulation with phorbol 12-myristate …

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Retrospective analysis of surgical pancreatic necrosectomy outcomes in patients with and without obesity

Roberto J. Valera, Mir Shanaz Hossain, Ronit Patnaik, Cesar Valdivieso et autres

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Hederacoside C Modulates EGF-Induced MUC5AC Mucin Gene Expression by Regulating the MAPK Signaling Pathway in Human Airway Epithelial Cells

Rajib Hossain, Mir Shanaz Hossain, Hyun Jae Lee, Choong Jae Lee

, which has been used for managing inflammatory respiratory diseases, in attenuating epidermal growth factor (EGF)-induced airway MUC5AC mucin gene expression. Human pulmonary mucoepidermoid NCI-H292 cells were pretreated with hederacoside C for 30 min and subsequently stimulated with EGF for 24 h. …

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Exploring the oncogenic role and prognostic value of CKS1B in human lung adenocarcinoma and squamous cell carcinoma

Mir Shanaz Hossain, Tariqul Islam Tusar, Nairita Ahsan Faruqui, Tanjim Ishraq Rahaman et autres

Introduction Lung cancer (LC) is a highly aggressive malignancy and remains a leading cause of cancer-related mortality worldwide. Non-small cell lung cancer (NSCLC), which includes adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC), accounts for the majority of these deaths. Due to the …

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Selective vs Routine Cholangiography Across a Health Care Enterprise

Abby Gross, Sayf Said, Chase J. Wehrle, Hanna Hong et autres

Importance: There is sparse literature on whether routine cholangiography (RC) vs selective cholangiography (SC) during cholecystectomy is associated with improved perioperative outcomes, regardless of whether an intraoperative cholangiogram (IOC) is performed. Objective: To compare perioperative outcomes of cholecystectomy between surgeons who routinely …

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Clinical and patient-reported outcomes following subtotal cholecystectomy: 10-year single-institution experience

Abby Gross, Hanna Hong, Mir Shanaz Hossain, Jenny H. Chang et autres

OBJECTIVE: Subtotal cholecystectomy provides a safe, bail-out alternative for difficult gallbladders. However, long-term outcomes comparing fenestrating and reconstituting subtotal cholecystectomy subtypes remain underexplored. METHODS: This retrospective cohort included patients who underwent subtotal cholecystectomy between 2010 and 2020 within a single hospital system. …

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Disease progression of side-branch intraductal papillary mucinous neoplasms following solid organ transplant

Chase J. Wehrle, Mir Shanaz Hossain, Jenny H. Chang, Breanna Perlmutter et autres

BACKGROUND: Branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) are becoming more prevalent with advanced medical imaging and account for most of pancreatic cystic neoplasms (PCNs). Most incidental lesions should be surveyed, with resection reserved for specific, high-risk cases. Solid organ transplantation candidates may …

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Consequences of a Surveillance Strategy for Side-branch Intraductal Pancreatic Mucinous Neoplasms

Chase J. Wehrle, Mir Shanaz Hossain, Breanna Perlmutter, Jenny H. Chang et autres

OBJECTIVE: To quantify the rate of progression in surveilled cysts and assess what factors should indicate delayed resection. BACKGROUND: Side-branch intraductal papillary mucinous neoplasms (SB-IPMNs) are increasingly discovered, making it challenging to identify which patients require resection, thus avoiding inappropriate treatment. Most …

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Predicting Mortality Before Interhospital Hospital for “Unseen” General Surgery Patients

Sayf Said, Corey K. Gentle, Abby Gross, Kelly Nimylowycz et autres

OBJECTIVE: Develop and validate a mortality risk calculator that could be utilized at the time of transfer, leveraging routinely collected variables that could be obtained by trained nonclinical transfer personnel. BACKGROUND: There are no objective tools to predict mortality at the time …

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