Wen-Jung Lo

Systemic bias in medical consensus: how flawed panels and lack of evidence can distort definitions and guidelines: the case of Vogt-Koyanagi-Harada disease

Carl P. Herbort Jr, Ioannis Papasavvas, Ahmed M. Abu El-Asrar, Abdulrahman F. AlBloushi et autres

BACKGROUND: The creation of diagnostic criteria for a disease is always challenging in medicine. Consensus meetings and expert's opinions are sometimes responsible for establishing useful and precise diagnostic criteria but, unfortunately, not all the consensus meetings are based on evidence-based conclusions. METHODS: …

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Non-Infectious Choroiditis Subdivided into Its Diverse Pathophysiological Sub-Groups Is the Best-Known and Most Appropriate Nomenclature to Date for the Reclassification and Diagnosis of Former White Dot Entities

Carl P. Herbort Jr, Sukhum Silpa-archa, Ioannis Papasavvas, Nadia Bouchenaki et autres

White dot syndromes (WDS), a purely descriptive term formulated in 1995, grouped inflammatory conditions primarily affecting the choroid that shared the clinical appearance of white dots on fundus examination, thus presenting similar white dots on fundus examination, which, however, had diverse pathophysiologies …

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Long-term outcomes and factors associated with visual recovery after small-gauge vitrectomy for infectious endophthalmitis: a 10-year experience at a single tertiary center in Taiwan

Chung-Hao Hsiao, Hung-Ju Chen, Chia-Jen Chang, Shih-Chao Feng et autres

PURPOSE: To evaluate long-term visual outcomes and prognostic factors after small-gauge pars plana vitrectomy (PPV) for exogenous endophthalmitis. METHODS: Single-center, retrospective cohort of 45 eyes (45 patients) undergoing PPV for exogenous endophthalmitis (June 2014-September 2024). Demographics, etiology, microbiology, surgical parameters, and outcomes …

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Enhancing Corneal Endothelial Cell Image Segmentation via Generative Data Augmentation and Transfer Learning

Hung‐Jen Chien, Pei-Shan Hsieh, Po-Yen Hsu, Wei-Lun Peng et autres

Corneal endothelium segmentation is crucial for clinical evaluation, but remains constrained by two significant challenges: the scarcity of high-quality annotations and the difficulty of reliably delineating complex pathological patterns. In particular, the corneal guttata exhibits high structural variability, resulting in limited and …

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Opposing pathophysiological concepts in multiple evanescent white dot syndrome: The great MEWDS schism

Carl P. Herbort, Ioannis Papasavvas, Abdulrahman F. AlBloushi, De‐Kuang Hwang et autres

Multiple evanescent white dot syndrome (MEWDS) is a benign posterior uveitis involving the outer retina-choriocapillaris complex. The clinical picture, since its first description in 1984, is well-established. Classified at the benign end of the choriocapillaritis spectrum, including, among others, idiopathic multifocal choroiditis, …

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SURGICAL AND REFRACTIVE OUTCOMES OF A NOVEL MODIFIED SCLERA-FIXATED RAYNER INTRAOCULAR LENS USING GORE-TEX SUTURE

Chung-Hao Hsiao, Yuan-Shao Cheng, Wen-Jung Lo, Hung‐Ju Chen et autres

PURPOSE: To evaluate the surgical outcomes of a novel modified scleral-fixated Rayner intraocular lens (IOL) with Gore-Tex suture. METHOD: Retrospective chart review was conducted who had sclera fixation Rayner IOL and pars plana vitrectomy utilizing Gore-Tex suture without scleral flap between November …

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The potential harmfulness of consensus meetings and/or opinion surveys in medicine to determine nosological classifications: The “white dots” case

Ioannis Papasavvas, Abdulrahman F. AlBloushi, Masaru Takeuchi, Yoshihiko Usui et autres

Dear Editor, This is a follow-up to the expert opinion published in this journal.[1] We are pleased to be able to mention that our article had a very positive impact inasmuch as the denomination of a major uveitis meeting abandoned the term …

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Acute Necrotizing Retinopathy After Xen Gel Stent Implantation

Wen-Jung Lo, Tung-Mei Kuang, Shih‐Jen Chen, De‐Kuang Hwang

PRÉCIS: We report a case of a 45-year-old woman who developed serous retinal detachment, hypotony, and retinal necrosis after Xen gel stent implantation. ABSTRACT: A 45-year-old woman developed sudden blurring of vision 4 days after Xen gel stent replacement surgery. Persistent hypotony, …

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Assessment of histological and immunohistochemical features of retinal tissues using a novel tissue submission procedure

Lei‐Chi Wang, Wen-Jung Lo, Yu-Bai Chou, Shih-Jen Chen et autres

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Same-Day Bilateral Intravitreal Dexamethasone Implants for the Treatment of Diabetic Macular Edema

Tai‐Chi Lin, Po-Chen Tseng, Tsui-Kang Hsu, Hsin-Wei Huang et autres

INTRODUCTION: The aim of this study was to evaluate the outcomes and complications associated with the use of same-day bilateral intravitreal dexamethasone (DEX) implants for the treatment of diabetic macular edema (DME). METHODS: This retrospective analysis of an open-label, multicenter, consecutive case …

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Bilateral Optic Disc Edema as an Initial Presentation of Acute Retinal Necrosis

Shih-Chuen Hsu, Wen-Jung Lo, Ting‐Yi Lin, Yu-Jang Chao et autres

PURPOSE: We reported a case of acute retinal necrosis (ARN) that presented as isolated bilateral optic disc edema. METHODS: A case report. CASE: A 68-year-old male with a 3-day history of progressive blurred vision presented with isolated bilateral optic disc edema. Through …

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Correlations between Clinical and Histopathologic Characteristics in Idiopathic Epiretinal Membrane

Lei‐Chi Wang, Wen-Jung Lo, Ya-Yun Huang, Yu-Bai Chou et autres

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