Disruption of serotonin homeostasis in intestinal organoids provides insights into drug-induced gastrointestinal toxicity
Georgia M Rouseti, Audrey Fischer, Nicole Rathfelder, Annick Waldt et autres
Drug-induced gastrointestinal toxicity is a frequent clinical adverse event that needs to be carefully monitored and managed to ensure patient compliance. While preclinical assessment of drug-induced gastrointestinal toxicity mostly relies on animal experimentation, intestinal organoids have gained increasing attention to identify gastrointestinal …
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Toxicology