Mary K. Guidinger

Disparities in Liver Transplantation

Amit K. Mathur, Douglas Earl Schaubel, Hui Zhang, Mary K. Guidinger et autres

BACKGROUND: We aimed to examine the association between recipient race/ethnicity and sex, donor liver quality, and liver transplant graft survival. METHODS: Adult non-status 1 liver recipients transplanted between March 1, 2002, and December 31, 2008, were identified using Scientific Registry of Transplant …

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Patient-Specific Prediction of ESRD after Liver Transplantation

Pratima Sharma, Nathan P. Goodrich, Douglas Earl Schaubel, Mary K. Guidinger et autres

Incident ESRD after liver transplantation (LT) is associated with high post-transplant mortality. We constructed and validated a continuous renal risk index (RRI) to predict post-LT ESRD. Data for 43,514 adult recipients of deceased donor LT alone (February 28, 2002 to December 31, …

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Short-Term Pretransplant Renal Replacement Therapy and Renal Nonrecovery after Liver Transplantation Alone

Pratima Sharma, Nathan P. Goodrich, Min Zhang, Mary K. Guidinger et autres

BACKGROUND AND OBJECTIVES: Candidates with AKI including hepatorenal syndrome often recover renal function after successful liver transplantation (LT). This study examined the incidence and risk factors associated with renal nonrecovery within 6 months of LT alone among those receiving acute renal replacement …

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Factors that affect deceased donor liver transplantation rates in the United States in addition to the model for end-stage liver disease score

Pratima Sharma, Douglas Earl Schaubel, Emily E. Messersmith, Mary K. Guidinger et autres

Under an ideal implementation of Model for End-Stage Liver Disease (MELD)-based liver allocation, the only factors that would predict deceased donor liver transplantation (DDLT) rates would be the MELD score, blood type, and donation service area (DSA). We aimed to determine whether …

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Epidemiology and outcome research in CKD 5D

Luís Coentrão, Cassius Norris Ribeiro, Carla Santos-Araújo, Ricardo Neto et autres

Introduction and Aims: The Portuguese National Health Service funds haemodialysis (HD) and peritoneal dialysis (PD) treatments using the same bundled payment system, since 2008. However, this package does not include hospitalizations, physician/emergency room visits, access-related procedures and patient transportation. The aim of …

Impact of MELD-Based Allocation on End-Stage Renal Disease After Liver Transplantation

Pratima Sharma, Douglas Earl Schaubel, Mary K. Guidinger, Nathan P. Goodrich et autres

The proportion of patients undergoing liver transplantation (LT), with concomitant renal dysfunction, markedly increased after allocation by the model for end-stage liver disease (MELD) score was introduced. We examined the incidence of subsequent post-LT end-stage renal disease (ESRD) before and after the …

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End–Stage Liver Disease Candidates at the Highest Model for End–Stage Liver Disease Scores Have Higher Wait–List Mortality Than Status–1A Candidates

Pratima Sharma, Douglas Earl Schaubel, Qi Ming Gong, Mary K. Guidinger et autres

UNLABELLED: Candidates with fulminant hepatic failure (Status-1A) receive the highest priority for liver transplantation (LT) in the United States. However, no studies have compared wait-list mortality risk among end-stage liver disease (ESLD) candidates with high Model for End-Stage Liver Disease (MELD) scores …

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Sex-Based Disparities in Liver Transplant Rates in the United States

Amit K. Mathur, Douglas Earl Schaubel, Qi Ming Gong, Mary K. Guidinger et autres

We sought to characterize sex-based differences in access to deceased donor liver transplantation. Scientific Registry of Transplant Recipients data were used to analyze n = 78 998 adult candidates listed before (8/1997-2/2002) or after (2/2002-2/2007) implementation of Model for End-Stage Liver Disease …

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Racial and ethnic disparities in access to liver transplantation

Amit K. Mathur, Douglas Earl Schaubel, Qi Ming Gong, Mary K. Guidinger et autres

Access to liver transplantation is reportedly inequitable for racial/ethnic minorities, but inadequate adjustments for geography and disease progression preclude any meaningful conclusions. We aimed to evaluate the association between candidate race/ethnicity and liver transplant rates after thorough adjustments for these factors and …

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Portal vein thrombosis and liver transplant survival benefit

Michael J. Englesbe, Douglas Earl Schaubel, Shijie Cai, Mary K. Guidinger et autres

Portal vein thrombosis (PVT) complicates the liver transplant operation and potentially affects waiting list survival. The implications on calculations of survival benefit, which balance both waiting list and posttransplant survival effects of PVT, have not been determined. The objective of this study …

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Liver Transplantation in the United States, 1999-2008

Paul Joseph Thuluvath, Mary K. Guidinger, John J. Fung, Lynt B. Johnson et autres

Changes in organ allocation policy in 2002 reduced the number of adult patients on the liver transplant waiting list, changed the characteristics of transplant recipients and increased the number of patients receiving simultaneous liver-kidney transplantation (SLK). The number of liver transplants peaked …

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Effect of Pretransplant Serum Creatinine on the Survival Benefit of Liver Transplantation

Pratima Sharma, Douglas Earl Schaubel, Mary K. Guidinger, Robert M. Merion

More candidates with creatinine levels >or= 2 mg/dL have undergone liver transplantation (LT) since the implementation of Model for End-Stage Liver Disease (MELD)-based allocation. These candidates have higher posttransplant mortality. This study examined the effect of serum creatinine on survival benefit among …

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