Tiziano Allice

Evaluation of HIV-1 transmitted drug-resistance among subtypes circulating from 2022 to 2024 in Italy: a refined analysis through next-generation sequencing

Daniele Armenia, Claudia Alteri, Valeria Micheli, Tiziano Allice et autres

BACKGROUND: Monitoring HIV-1 subtype circulation and transmitted drug resistance (TDR) remains a key priority, particularly since the rollout of high-sensitivity next-generation sequencing (NGS). METHODS: Routine plasma HIV-1 RNA NGS genotyping data were collected from newly diagnosed individuals in Italy over 2022-24. HIV-1 …

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Full reservoirs and poor adherence: two cases of symptomatic HIV cerebrospinal fluid escape with tenofovir alafenamide/emtricitabine/bictegravir

Andrea Calcagno, Lipani Carola, Rizzello Barbara, Perinzano Andrea et autres

BACKGROUND: Symptomatic cerebrospinal fluid (CSF) escape is an uncommon presentation in people with HIV with undetectable or low-level HIV RNA while on combination antiretroviral treatment (cART). Only one case has been reported in a patient receiving bictegravir-based therapy so far. METHODS: We …

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Invisible burden: Prevalence of Chagas disease in Latin American migrants in Turin, North-Western Italy – A STROBE compliant-cross-sectional study

Elisa Burdino, Andrea Bernardi, Francesco Cerutti, Alessia Di Vincenzo et autres

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Comparison of Different HIV-1 Resistance Interpretation Tools for Next-Generation Sequencing in Italy

Daniele Armenia, Luca Carioti, Valeria Micheli, Isabella Bon et autres

BACKGROUND: Next-generation sequencing (NGS) is gradually replacing Sanger sequencing for HIV genotypic drug resistance testing (GRT). This work evaluated the concordance among different NGS-GRT interpretation tools in a real-life setting. METHODS: Routine NGS-GRT data were generated from viral RNA at 11 Italian …

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Sequential or Combination Treatments as Rescue Therapies in Immunocompromised Patients with Persistent SARS-CoV-2 Infection in the Omicron Era: A Case Series

Bianca Maria Longo, Francesco Venuti, Alberto Gaviraghi, Tommaso Lupia et autres

Prolonged SARS-CoV-2 infections are widely described in immunosuppressed patients, but safe and effective treatment strategies are lacking. We aimed to outline our approach to treating persistent COVID-19 in patients with immunosuppression from different causes. In this case series, we retrospectively enrolled all …

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Transient plasma viral rebound after SARS-CoV-2 vaccination in an exceptional HIV-1 elite controller woman

Luciana Di Girolamo, Sergio Maria Ferrara, Giusto Trevisan, Beatriz M. Longo et autres

BACKGROUND: Elite controllers are able to control viral replication without antiretroviral therapy. Exceptional elite controllers do not show disease progression for more than 25 years. Different mechanisms have been proposed and several elements of both innate and adaptive immunity are implicated. Vaccines …

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Transient Plasma Viral Rebound After Sars-cov-2 Vaccination in an Exceptional Hiv-1 Elite Controller Woman

Laura Di Girolamo, Giulia Trevisan, Bianca Maria Longo, Tiziano Allice et autres

Abstract Background Elite controllers are able to control viral replication without antiretroviral therapy. Exceptional elite controllers do not show disease progression for more than 25 years. Different mechanisms have been proposed and several elements of both innate and adaptive immunity are implicated. …

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Fast and reliable real life data on COVID-19 triaging with ID NOW

Elisa Burdino, Francesco Cerutti, Maria Grazia Milia, Tiziano Allice et autres

In the context of SARS-CoV-2 pandemic, rapid and easy-to-perform diagnostic methods are essential to limit the spread of the virus and for the clinical management of COVID-19 patients. Although real-time polymerase chain reaction remains the "gold standard" to diagnose acute infections, this …

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SARS-CoV-2 microfluidic antigen point-of-care testing in Emergency Room patients during COVID-19 pandemic

Elisa Burdino, Francesco Cerutti, Francesco Panero, Tiziano Allice et autres

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GENDER ANALYSIS ON COVID-19 DATA IN PIEMONTE: THE VIRUS PREFERS MEN

Silvia De Francia, Alessandro Ferretti, Daniele Mancardi, Chiara Di Francesco et autres

Failure on voxilaprevir, velpatasvir, sofosbuvir and efficacy of rescue therapy

Julia Dietz, Velia Chiara Di Maio, Adolfo de Salazar, Dolores Merino et autres

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Urgent need of rapid tests for SARS CoV-2 antigen detection: Evaluation of the SD-Biosensor antigen test for SARS-CoV-2

Francesco Cerutti, Elisa Burdino, Maria Grazia Milia, Tiziano Allice et autres

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