Yanchen Li

Identification of novel target of quinazolinones active molecules and bioactivity & labeling preference of photocrosslinkers

Yanchen Li, Tingting Liu, Kun Zhang, Jin Wang et autres

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Discovery of drug target for vascular normalization through multifunctional photoaffinity probes

Yanchen Li, Jin Wang, Junyu Zhang, Tingting Liu et autres

cn (code pays fourni par la source)

Identification of RIPK1 as a novel target for angiogenesis regulation based on ABT-869 conjugated photoaffinity probes

Yanchen Li, Tingting Liu, Weihua Cheng, Lifeng Zhao et autres

cn (code pays fourni par la source)

Discovery of a Targeted Prodrug System Activated by Reactive Oxygen Species to Enhance Diagnostic and Therapeutic Efficacy of Photodynamic Therapy

Jinfeng Wang, Yanchen Li, Junyu Zhang, Tingting Liu et autres

Photodynamic therapy (PDT) alone is not as effective as expected due to its poor targeting and influence by the tumor microenvironment. In this study, combined with the strategy of controlled release and fluorescence illumination, we developed a cancer-targeted and activated photodynamic functional …

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A patent perspective of antiangiogenic agents

Junyu Zhang, Jin Wang, Yanchen Li, Xiaoyan Pan et autres

INTRODUCTION: Angiogenesis plays a crucial role in the development of numerous vascular structures and is involved in a variety of physiologic and pathologic processes, including psoriasis, diabetic retinopathy, and especially cancer. By obstructing the process of angiogenesis, these therapies effectively inhibit the …

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Discovery of intracellular self-assembly protein degraders driven by tumor-specific activatable bioorthogonal reaction

Ru Si, Ping Hai, Yongbiao Zheng, Jin Wang et autres

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Discovery of novel antibody-drug conjugates bearing tissue protease specific linker with both anti-angiogenic and strong cytotoxic effects

Yanchen Li, Ru Si, Jin Wang, Ping Hai et autres

cn (code pays fourni par la source)

Discovery of novel PROTACs based on multi-targeted angiogenesis inhibitors

Ru Si, Ping Hai, Yongbiao Zheng, Nanxin Liu et autres

cn (code pays fourni par la source)