Wayne D. Old

Health Status Outcomes With Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting in ISCHEMIA

Chetan Prakash Huded, John A. Spertus, Philip G. Jones, Sean Michael O'Brien et autres

BACKGROUND: In ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches), an invasive strategy demonstrated better health status outcomes than a conservative strategy in patients with chronic coronary disease (CCD). Some previous studies have shown greater health status benefits …

us, nz (code pays fourni par la source)

Vericiguat for patients with heart failure and reduced ejection fraction across the risk spectrum: an individual participant data analysis of the VICTORIA and VICTOR trials

Faiez M. Zannad, Christopher M. O’Connor, Javed Butler, Ciaran J. McMullan et autres

BACKGROUND: Following completion of the VICTORIA trial, vericiguat was approved for the treatment of worsening heart failure with reduced ejection fraction (HFrEF) and received a class IIb recommendation in European and North American guidelines. The subsequent VICTOR trial evaluated the use of …

fr, us, ch, ca, sg, pl, it, de, nl (code pays fourni par la source)

Vericiguat in patients with chronic heart failure and reduced ejection fraction (VICTOR): a double-blind, placebo-controlled, randomised, phase 3 trial

Javed Butler, Ciaran J. McMullan, Kevin Joseph Anstrom, Irina Barash et autres

us, ch, ca, sg, pl, it, co, de, nl, fr (code pays fourni par la source)

Anticoagulation Timing in Acute Stroke With Atrial Fibrillation According to Chronic Kidney Disease: The OPTIMAS Trial

Philip S. Nash, Hakim‐Moulay Dehbi, Norin Ahmed, Liz Arram et autres

BACKGROUND: Patients with chronic kidney disease (CKD) are at increased risk of ischemic stroke (IS) and intracerebral hemorrhage, so the safety and efficacy of early direct oral anticoagulant (DOAC) initiation in those with CKD are of clinical relevance. METHODS: OPTIMAS (Optimal Timing …

gb, us, ch, dk, se (code pays fourni par la source)

Safety and Efficacy of SGLT2 Inhibitors in Heart Transplant Recipients

Laura Ines Furlong, Amanda I. Ingemi, Jonas Mandel, Anh D. Bui et autres

us (code pays fourni par la source)

Evaluating the Appropriate Use Criteria for Coronary Revascularization in Stable Ischemic Heart Disease Using Randomized Data From the ISCHEMIA Trial

James Slater, David Joel Maron, Philip G. Jones, Sripal Bangalore et autres

BACKGROUND: The appropriate use criteria for revascularization of stable ischemic heart disease have not been evaluated using randomized data. Using data from the randomized ISCHEMIA trial (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches; July 2012 to January 2018, …

us (code pays fourni par la source)

Hemodynamics-Based Study Of Aquapheresis For Volume Overload In Patients With Heart Failure

Wayne D. Old, John M. Herre, Lauren Feeney, Spencer Chee et autres

us (code pays fourni par la source)

Relationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial

Harmony R. Reynolds, Courtney B. Page, Leslee J. Shaw, Daniel S. Berman et autres

BACKGROUND: The relationship between the extent and severity of stress-induced ischemia and the extent and severity of anatomic coronary artery disease (CAD) in patients with obstructive CAD is multifactorial and includes the intensity of stress achieved, type of testing used, presence and …

us, ca, gb, pl, in, lt, de, pt, fr, be (code pays fourni par la source)

Seated Pulmonary Artery Pressure Monitoring in Patients With Heart Failure

Jason L. Guichard, Eric L. Bonno, Michael E. Nassif, Taiyeb M. Khumri et autres

BACKGROUND: Monitoring supine pulmonary artery pressures to guide heart failure (HF) management has reduced HF hospitalizations in select patients. OBJECTIVES: The purpose of this study was to evaluate the effect of managing seated mean pulmonary artery pressure (mPAP) with the Cordella Pulmonary …

us, be (code pays fourni par la source)

Factors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial

Radosław Pracoń, John A. Spertus, Samuel Broderick, Sripal Bangalore et autres

BACKGROUND: ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) did not find an overall reduction in cardiovascular events with an initial invasive versus conservative management strategy in chronic coronary disease; however, there were conservative strategy participants who underwent …

pl, us, ru, gb, br, in, ca (code pays fourni par la source)

Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial

Harmony R. Reynolds, Derek D. Cyr, C. Noel Bairey Merz, Leslee J. Shaw et autres

Background Women with chronic coronary disease are generally older than men and have more comorbidities but less atherosclerosis. We explored sex differences in revascularization, guideline‐directed medical therapy, and outcomes among patients with chronic coronary disease with ischemia on stress testing, with and …

us, se, be, ru, gb, pt (code pays fourni par la source)

The utilization and safety of apixaban for therapeutic anticoagulation in heart transplant population requiring routine endomyocardial biopsies

Kristen E. Lindauer, Amanda I. Ingemi, Megan R. McMahon, Alicia Beth Lichvar et autres

PURPOSE: Routine endomyocardial (EM) biopsies pose a challenge in the management of heart transplant recipients requiring anticoagulation. Apixaban is a direct-acting oral anticoagulant (DOAC) with a short half-life allowing for brief interruptions of anticoagulation for procedures. The study objective was to determine …

us (code pays fourni par la source)