Yuanshi Tian

Natural killer cell-mediated immunosurveillance modulates liver cancer evolution through cancer stemness enhancement and lipid metabolism reprogramming

Liang Shi, Boqiang Liu, Ruya Sun, Jing He et autres

Tumor evolution enables liver cancer cells to acquire survival advantages and evade therapy-induced cell death. However, the role of natural killer (NK) cells in liver cancer evolution remains unclear. Here, we establish immune-humanized spatiotemporal liver cancer models and integrate single-cell, spatial transcriptomic, …

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Lactate Metabolic Reprogramming Mediated by CircRNA–LDHA Complex Facilitates Innate Immune Evasion of Liver Cancer

Hao Shen, Boqiang Liu, Jing Yu He, Weijun Zhao et autres

Hepatocellular carcinoma (HCC) exhibits a distinctive metabolic profile that engenders a highly immunosuppressive tumor immune microenvironment, posing significant challenges for targeted therapy. Notably, natural killer (NK) cells, which are abundant in the liver and play a crucial role in innate immunity, are …

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WITHDRAWN: Natural Killer Cell-Mediated Immunosurveillance Drives Liver Cancer Evolution Through Cancer Stemness Enhancement and Lipid Metabolism Reprogramming

Liang Shi, Boqiang Liu, Ruya Sun, Jing He et autres

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WITHDRAWN: Natural Killer Cell-Mediated Immunosurveillance Drives Liver Cancer Evolution Through Cancer Stemness Enhancement and Lipid Metabolism Reprogramming

Liang Shi, Boqiang Liu, Ruya Sun, Jing He et autres

cn (code pays fourni par la source)

Echocardiographic features and outcomes of fetuses with isolated restrictive foramen ovale or redundant foramen ovale flap using atrial septum excursion index

Yuanshi Tian, Xinxin Chen, Jiehuai Zheng, Lijiong Chen et autres

PURPOSE: This study was designed to investigate the application value of the atrial septum excursion index (ASEI) in fetuses with isolated restrictive foramen ovale (RFO) or redundant foramen ovale flap (RFOF) and the outcomes of these fetuses. METHODS: This was a retrospective …

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Cytoskeleton remodeling mediated by circRNA-YBX1 phase separation suppresses the metastasis of liver cancer

Boqiang Liu, Hao Shen, Jing He, Binghan Jin et autres

Metastasis, especially intrahepatic, is a major challenge for hepatocellular carcinoma (HCC) treatment. Cytoskeleton remodeling has been identified as a vital process mediating intrahepatic spreading. Previously, we reported that HCC tumor adhesion and invasion were modulated by circular RNA (circRNA), which has emerged …

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The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis

Boqiang Liu, Yuanshi Tian, Jing Yu He, Qiuxia Gu et autres

BACKGROUND: Nonalcoholic steatohepatitis (NASH) occupies a substantial proportion of chronic liver disease worldwide, of which pathogenesis needs further research. Recent studies have demonstrated the significant roles of circular RNAs (circRNAs) in NASH, while the function of a novel type of circRNAs, namely …

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The Application of Knowledge Distillation toward Fine-Grained Segmentation for Three-Vessel View of Fetal Heart Ultrasound Images

Qiwen Cai, Ran Chen, Lu Li, Chao Hsun Huang et autres

Objectives: Measuring anatomical parameters in fetal heart ultrasound images is crucial for the diagnosis of congenital heart disease (CHD), which is highly dependent on the clinical experience of the sonographer. To address this challenge, we propose an automated segmentation method using the …

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The Potential of mecciRNA in Hepatic Stellate Cell to Regulate Progression of Nonalcoholic Hepatitis

Boqiang Liu, Yuanshi Tian, Jing He, Qiuxia Gu et autres

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Additional file 4 of The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis

Boqiang Liu, Yuanshi Tian, Jing He, Qiuxia Gu et autres

Additional file 4: Supplementary Table. 1 The 2000 mRNAs Targeted by 26 miRNAs in miRNet Database.

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Additional file 7 of The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis

Boqiang Liu, Yuanshi Tian, Jing He, Qiuxia Gu et autres

Additional file 7: Supplementary Table. 4 The 419 mRNAs Regulated by mecciRNA-miRNA Network in Hepatocytes.

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Additional file 8 of The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis

Boqiang Liu, Yuanshi Tian, Jing He, Qiuxia Gu et autres

Additional file 8: Supplementary Table. 5 The 273 Differentially Expressed Genes Between Cluster 1 and Cluster 2.

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