Xueqian Ouyang

Apelin-13 drives VSMC proliferation and atherosclerosis through REEP5-dependent disruption of ER-mitochondria coupling and glycolytic shift

Huimei Liu, Wei Chen, Hui Mao, Ruirui Lu et autres

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Emerging roles of platelet DNA in cancer detection and noninvasive prenatal testing

Manli Ding, Xiaohui Huang, Xueqian Ouyang, Fengting Guo et autres

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Risk prediction models for cardiac rupture after acute myocardial infarction: a systematic review and meta-analysis

Yijun Mao, Qiang Liu, Hui Fan, Xueqian Ouyang et autres

Background: Cardiac rupture (CR) is a catastrophic complication of acute myocardial infarction (AMI), accounting for 10%-20% of AMI-related deaths despite its low incidence. Several risk prediction models have been developed, but their methodological quality and clinical applicability remain uncertain. This study systematically …

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Psychological stress-driven modulation of YAP1 signaling: Mechanistic pathways linking stress biology to tumor progression

Xiu-Wen Ma, Xueqian Ouyang, Zhenyu Meng, Yao Huang et autres

Psychological distress is increasingly recognized as a biologically active contributor to cancer progression, and emerging evidence identifies yes-associated protein 1 (YAP1) as a central molecular node through which stress-related signaling influences tumor behavior. As a mechanosensitive transcriptional co-activator within the Hippo pathway, …

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“Zero-distance” photocrosslinking: a paradigm shift in probing DNA-protein dynamics

Fengting Guo, Sisi Fan, Xueqian Ouyang, LanFang Li et autres

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Risk prediction models for permanent pacemaker implantation following transcatheter aortic valve replacement: a systematic review and meta-analysis

Qiang Liu, Hui Fan, Wenjing He, Xueqian Ouyang et autres

Objective: To systematically evaluate the methodological quality and predictive performance of risk prediction models for permanent pacemaker implantation (PPMI) following transcatheter aortic valve replacement (TAVR), identify key predictive factors, and assess the risk of bias and clinical applicability of these models. Methods: …

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Risk prediction model for post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis

Yufeng Mao, Hui Fan, Wenjing He, Cheng Zhang et autres

BACKGROUND: Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common and clinically significant complication of ERCP, with an incidence of 3.5-9.7% in general populations and up to 14.7% in high-risk groups, leading to considerable morbidity, mortality, and healthcare costs. Although numerous multivariable …

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The physiological and pathogenic roles of yes-associated protein/transcriptional co-activator with PDZ-binding motif in bone or skeletal motor system-related cells

Yao Huang, Xueqian Ouyang, Jinghua Tan, Zhenyu Meng et autres

Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are the primary downstream effectors of the Hippo signaling pathway. This pathway plays a crucial role in regulating organ size, maintaining tissue homeostasis, and controlling cellular processes such as fate determination and …

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Advances in the clinical diagnosis and treatment of multiple-level noncontiguous spinal fractures

Huarong Chen, Mingxiang Zou, Yiguo Yan, Xueqian Ouyang et autres

Multiple-level noncontiguous spinal fractures (MNSF) are spinal fractures that involve at least 2 sites and are characterized by the presence of one intact vertebra or intact functional spinal unit between the fractured vertebrae. MNSF account for 2.5-19% of all spinal fractures. MNSF …

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Prediction Models for Post‐Stroke Hospital Readmission: A Systematic Review

Yufeng Mao, Qiang Liu, Hui Fan, Erqing Li et autres

OBJECTIVE: This study aims to evaluate the predictive performance and methodological quality of post-stroke readmission prediction models, identify key predictors associated with readmission, and provide guidance for selecting appropriate risk assessment tools. METHODS: A comprehensive literature search was conducted from inception to …

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Intercellular Mitochondrial Transfer: The Novel Therapeutic Mechanism for Diseases

Huimei Liu, Hui Mao, Xueqian Ouyang, Ruirui Lu et autres

Mitochondria, the dynamic organelles responsible for energy production and cellular metabolism, have the metabolic function of extracting energy from nutrients and synthesizing crucial metabolites. Nevertheless, recent research unveils that intercellular mitochondrial transfer by tunneling nanotubes, tumor microtubes, gap junction intercellular communication, extracellular …

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A unique case of benign notochord cell tumor in which the cervical vertebral body and its accessories were eroded by the tumor

Yao Huang, Jingbo Xue, Jinghua Tan, Xueqian Ouyang et autres

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