Dorcas A. Gado

Orthopoxvirus Antibodies in Feral Mammals in Mpox Outbreak Areas, Nigeria, 2021–2022

Adeyinka Jeremy Adedeji, Clement Adebajo Meseko, Ismaila Ademola Shittu, Nanven Maurice et autres

We analyzed tissue and serum samples from 124 wild animals from communities with confirmed mpox cases in Nigeria. Tissue samples were PCR-negative, but serum samples from 8 animals (6.45%)-3 feral cats, 4 giant pouched rats, and 1 shrew-revealed Orthopoxvirus antibodies, suggesting these …

Emergence and Rapid Spread of a New Reassortant High Pathogenicity H5N1 Clade 2.3.4.4b Avian Influenza Virus in Nigeria

Clement Adebajo Meseko, Bianca Zecchin, Emilie Go-Maro, Marta Dianati et autres

Over the past two decades, West Africa has experienced recurrent incursions of Goose/Guangdong-lineage highly pathogenic avian influenza (HPAI) A(H5N1), with Nigeria as a hotspot for repeated introductions and sustained circulation. Since 2021, European-origin clade 2.3.4.4b H5Nx genotypes, particularly EA-2020-C, have predominated in …

Nigéria, it, Togo (code pays fourni par la source)

High Seroprevalence and Risk Factors of Crimean-Congo Hemorrhagic Fever Virus in Camels at Livestock Markets in Border Regions, Nigeria, 2023–2024

David Odion Ehizibolo, Olumuyiwa Oyekan, Nicodemus Nnabuike Mkpuma, Habibu Haliru et autres

BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) is a highly fatal, tick-borne zoonosis in humans for which no licensed vaccines exist. Camels are important hosts of Hyalomma ticks, yet data on their role in CCHF epidemiology in Nigeria are limited. This study assessed seroprevalence …

Nigéria, us (code pays fourni par la source)

Multiplex PCR to Differentiate Monkeypox Virus Clades

Christopher T. Williams, Alessandra Romero-Ramirez, Adeleye Adesola Semiu, Samuel Oluwafunmbi Ifabumuyi et autres

We designed a multiplex quantitative PCR to differentiate monkeypox virus clades. For clinical samples collected in the United Kingdom and Nigeria, sensitivity was 78% (95% CI 67.67%-86.14%) and specificity 94% (95% CI 80.84%-99.30%); for samples with cycle thresholds <35, sensitivity was 98% …

Seroprevalence of Crimean-Congo Hemorrhagic Fever and Rift Valley Fever Viruses Among Ruminants in Nigeria: A Descriptive Epizootiological Analysis

David Odion Ehizibolo, Olumuyiwa Oyekan, Nicodemus Nnabuike Mkpuma, Dorcas A. Gado et autres

Crimean-Congo hemorrhagic fever (CCHF) and Rift Valley fever (RVF) are major zoonotic diseases, spread by arthropods, with livestock serving as amplifying hosts. Despite Nigeria's large ruminant population and robust cross-border animal trade, data on the seroprevalence of the viral agents causing these …

Nigéria, Tanzanie, us (code pays fourni par la source)

A Multiplex qPCR to Differentiate Monkeypox Virus Clades

Christopher T. Williams, A. Ramirez, Adeleye Adesola Semiu, Samuel Oluwafunmbi Ifabumuyi et autres

Abstract We designed a multiplex qPCR to differentiate monkeypox virus clades. In evaluations using clinical samples collected in the UK and Nigeria, the assay had an overall sensitivity of 78% (95% CI: 67.67% to 86.14%) and specificity of 94% (95% CI: 80.84% …

gb, Nigéria, vn, République démocratique du Congo (code pays fourni par la source)

Serological and Molecular Detection of Low Pathogenic Avian Influenza Subtype H9N2 in Commercial Poultry Flock in Kaduna and Kano State Nigeria

Nicodemus Nnabuike Mkpuma, Lukman Muftahu Oyedeji, Alexander Oluyinka Akintule, Chinonyerem N. Chinyere et autres

The poultry business in Nigeria has been severely affected by highly pathogenic avian influenza (HPAI), particularly the H5 variant. Unlike H5 and H7 subtypes, low pathogenic strains like the H9N2 are not notifiable to the OIE. However, in many instances in the …

Nigéria (code pays fourni par la source)

Applied One Health: Nigeria National Veterinary Research Institute COVID-19 pandemic response

Clement Adebajo Meseko, Ismaila Ademola Shittu, Olayinka Oluwafemi Asala, Adeyinka Jeremy Adedeji et autres

The COVID-19 pandemic has caused the death of 7.1 million people worldwide as of 7 July 2024. In Nigeria, the first confirmed case was reported on 27 February 2020, subsequently followed by a nationwide spread of SARS-CoV-2 with morbidity and mortality reaching …

Nigéria (code pays fourni par la source)

Review of Emerging and Re-Emerging Zoonotic Pathogens of Dogs in Nigeria: Missing Link in One Health Approach

Dorcas A. Gado, David Odion Ehizibolo, Clement Adebajo Meseko, Neil Euan Anderson et autres

Dogs live in close contact with humans as pets, for hunting, for security, and as a source of income. In addition, the meat is also consumed by some tribes in Nigeria. Dogs could therefore serve as reservoirs, carriers, and transmitters of zoonotic …

gb, Nigéria (code pays fourni par la source)

Pharmacological properties and radical scavenging potential of 5-demethyl sinensetin obtained from Loxostylis alata

Dorcas A. Gado, Muna Ali Abdalla, Marthie Magdaleen Ehlers, Lyndy Joy McGaw

Loxostylis alata Spreng. ex Rchb. (Anacardiaceae) is used in South African traditional medicine to alleviate labor pain and to boost the immune system. A polymethoxyflavone (PMF), identified as 5-hydroxy-4′,5′,6,7-tetramethoxyflavone (5-demethyl sinensetin) isolated from the ethyl acetate extract of L. alata, was evaluated …

Afrique du Sud, Nigéria, Soudan (code pays fourni par la source)

In vitro anti-biofilm effects of Loxostylis alata extracts and isolated 5-demethyl sinensetin on selected foodborne bacteria

Dorcas A. Gado, Muna Ali Abdalla, Joseph Omorogiuwa Erhabor, Marthie Magdaleen Ehlers et autres

Bacterial biofilms pose health challenges both in clinical environments and the food industry. Major foodborne bacterial pathogens form biofilms on surfaces and persist, causing infections in humans that may be difficult to treat. Conventional use of antibiotics is fast becoming ineffective due …

Afrique du Sud, Nigéria, Soudan (code pays fourni par la source)

Attitude towards wearing face mask increases vulnerability of men over women and the risk of Covid-19 pandemic spread in Jos-South metropolis, Plateau State, Nigeria

Bitrus Inuwa, Judith Bakam, Hassan Ismail Musa, Idris U. Hambali et autres

Covid-19 pandemic has hit many countries and put the majority of the public health system to test globally. Mandatory use of facemask was among policies set by the government to contain the spread of the novel disease. But citizens’ attitudes and compliance …

Nigéria (code pays fourni par la source)