Martin Brüne

Analysis of brain volumetry and functional connectivity during resting state in patients with borderline personality disorder

Vera Flasbeck, Björn Enzi, Georg Juckel, Martin Brüne

BACKGROUND: Borderline Personality Disorder (BPD) involves affective instability, impaired emotion regulation, and self-injurious behavior, often linked to childhood adversity. Although prefrontal and insular abnormalities have been reported, the relationship between structural and functional changes in BPD is not well characterized. METHODS: We …

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Menstrual cycle and hormonal contraceptive intake alter the electrophysiological signature of selective auditory spatial attention

Michael-Christian Schlueter, Marlies Pinnow, Martin Brüne, Jörg Lewald

Abstract The fluctuations in steroid hormones associated with the female menstrual cycle have been suggested to modulate attentional brain processes. This study focused on cycle-dependent changes in the electrophysiological correlates of sound localization in a cocktail-party task, which has been shown to …

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Ethno-evolutionary insights and missed critical periods hypothesis of Autism Spectrum Condition

Costanza Colombi, Martin Brüne

This article proposes an ethno-evolutionary "missed critical periods" hypothesis of Autism Spectrum Condition (ASC), integrating developmental neuroscience with anthropological and ethological perspectives. Drawing on evidence that the first year of life is characterized by heightened brain plasticity and rapidly narrowing sensory-social attunement, …

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Reduced activation in empathy core regions during observation of social interactions in patients with borderline personality disorder: an fMRI-study

Vera Flasbeck, Björn Enzi, Georg Juckel, Martin Brüne

Patients with Borderline personality disorder (BPD) are known to exhibit aberrant empathy and heightened sensitivity to social threat. However, the neural mechanisms underlying these observations are not fully understood. In the present study, we therefore sought to assess empathy for somatic and …

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Personality Disorders and Human Evolution: An Integrative Meta-synthesis

Simone Cheli, Sara Bui, Martin Brüne

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Evolutionary systems therapy for personality pathology: a proof-of-concept single-arm trial

Simone Cheli, Martin Brüne, Gil Goldzweig, Sara Bui et autres

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Disentangling empathy for psychological and physical pain in borderline personality disorder: the interplay with clinical features and emotional competence

Margherita Bechi, Martin Brüne, Giulia Agostoni, Roberta Bortolla et autres

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Evolutionary Psychiatry Before, During and After Kraepelin and His Times

Paul St John-Smith, Martin Brüne, Riadh Abed

Abstract This chapter considers the influence of Darwin’s theory of evolution by natural selection on psychiatry and psychology before Kraepelin and on Kraepelin as well as their more modern incarnation after Kraepelin. In particular, the use, misuse and misinterpretation of Darwin’s theories …

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Theory of mind skill predicts anticipatory guilt-proneness in schizophrenia

Rivkah Barbanel, Nathan Caruana, Robyn A. Langdon, Martin Brüne et autres

BACKGROUND AND HYPOTHESIS: Adaptive management of guilt and shame is regulated by social approach and withdrawal and thus relates to the quantity and quality of our social interactions. People with schizophrenia (SZ) self-report reduced guilt-proneness compared to healthy controls (HC). However, previous …

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Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

Nico J. Diederich, Martin Brüne, John S. Allen, Nicole Bender et autres

Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease. Here, we discuss evolutionary concepts relevant to understanding human brain diseases, on the …

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Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

Nico J. Diederich, Martin Brüne, John S. Allen, Nicole Bender et autres

Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease. Here, we discuss evolutionary concepts relevant to understanding human brain diseases, on the …

Personality Disorders and Human Evolution: An Integrative Meta-synthesis

Simone Cheli, Sara Bui, Martin Brüne

An increasing body of evidence, spanning both qualitative and quantitative methodologies, points to the clinical utility of an evolutionarily informed conceptualization of personality disorders. Evolutionarily informed measures and mechanisms exhibit associations with a range of clinical indicators. Concurrently, various theoretical studies and …