Jiajun Ling

Diosgenin ameliorates CLP-induced sepsis in mice via suppressing inflammatory responses and preserving intestinal mucosal barrier integrity

Yuanyuan Li, Jiajia Zeng, Qiting Huang, Xianfei Wang et autres

BACKGROUND: Diosgenin, a well-known steroid sapogenin, has demonstrated anti-inflammatory effects; however, its therapeutic potential for sepsis remains unclear. Intestinal barrier dysfunction is a critical contributor to lethal sepsis, a systemic inflammatory response syndrome. This study investigated the protective effects of diosgenin on …

cn (code pays fourni par la source)

Toward comprehensive traffic scene understanding: a benchmark and detector for traffic object detection in smart city surveillance

Qimin Cheng, Jiajun Ling, Yingjie Du, Qunshan Zhao

Traffic object detection serves as a critical enabler of intelligent transportation systems (ITS). However, it faces multi-dimensional challenges in complex scenarios, including object heterogeneity, scene adaptation, and the trade-off between accuracy and real-time performance. To mitigate these issues, we propose TSO-DETR, a …

cn, gb (code pays fourni par la source)

Successful treatment of refractory cancer therapy-induced thrombocytopenia in a breast cancer patient using romiplostim N01: A case report

Peng Liu, Enlai Dong, Yiming Jiang, Lin Chen et autres

RATIONALE: Cancer therapy-induced thrombocytopenia (CTIT) is a frequent complication in cancer treatment, with severe cases posing risks of bleeding and hindering therapeutic progress. PATIENT CONCERNS: A breast cancer patient developed refractory CTIT following multiple lines of chemotherapy. Despite treatment with various thrombopoietic …

cn (code pays fourni par la source)

Quality analysis of AIS data derived from Haiyang (HY) series satellites

Xi Ding, Songtao Ai, Jiajun Ling, Jiachun An et autres

cn (code pays fourni par la source)

InstLane Dataset and Geometry-Aware Network for Instance Segmentation of Lane Line Detection

Qimin Cheng, Jiajun Ling, Yunfei Yang, Kaiji Liu et autres

Despite impressive progress, obtaining appropriate data for instance-level lane segmentation remains a significant challenge. This limitation hinders the refinement of granular lane-related applications such as lane line crossing surveillance, pavement maintenance, and management. To address this gap, we introduce a benchmark for …

cn, us (code pays fourni par la source)

Zigzag Attention: A Structural Aware Module For Lane Detection

Jiajun Ling, Yifan Chen, Qimin Cheng, Xiao Huang

Lane detection presents a formidable challenge in the realm of autonomous driving, given the real-time processing demands, diverse acquisition conditions, and the unique elongated and angular characteristics of lane lines. While a multitude of network design strategies have been proposed to tackle …

cn, us (code pays fourni par la source)

Towards Efficient Risky Driving Detection: A Benchmark and a Semi-Supervised Model

Qimin Cheng, LI Huan-ying, Yunfei Yang, Jiajun Ling et autres

Risky driving is a major factor in traffic incidents, necessitating constant monitoring and prevention through Intelligent Transportation Systems (ITS). Despite recent progress, a lack of suitable data for detecting risky driving in traffic surveillance settings remains a significant challenge. To address this …

cn, us (code pays fourni par la source)

Chlorin e6-loaded sonosensitive magnetic nanoliposomes conjugated with the magnetic field for enhancing anti-tumor effect of sonodynamic therapy

Haimei Zhu, Su-Su Huang, Jin-Jie Tian, Lisheng Wang et autres

In sonodynamic therapy (SDT), when Chlorin e6 (Ce6) accumulates in tumor tissues, its anti-tumor effect can be achieved by ultrasound activation. To increase the local drug concentration of Ce6 in tumor cells, we had established a novel drug delivery system, Ce6-loaded sonosensitive …

cn (code pays fourni par la source)

Hydroxycamptothecin liposomes based on thermal and magnetic dual-responsive system: preparation, in vitro and in vivo antitumor activity, microdialysis-based tumor pharmacokinetics

Haimei Zhu, Jin-Hui Gu, Yi Fen Xie, Bo Xie et autres

Due to the absence of lactone form of hydroxycamptothecin, the commercially available hydroxycamptothecin injection exhibits inefficient therapeutic effects. In this study, we constructed a novel delivery system (thermosensitive magnetic liposomes) that protects lactone form of hydroxycamptothecin from blood or water. After hydroxycamptothecin …

cn (code pays fourni par la source)

Influence of Rare Earth Additive on Preparation and Corrosion Resistance of Ni-Fe Alloy Coating

Yanhua Shi, Boya Hao, Tong Nan, Jiajun Ling et autres

An LC/MS quantitative and microdialysis method for cyclovirobuxine D pharmacokinetics in rat plasma and brain: The pharmacokinetic comparison of three different drug delivery routes

Jiabao Wei, Qiao Lai, Stepan P. Shumyak, Lanfang Xu et autres

cn, us (code pays fourni par la source)

[Pharmacokinetics of nicotine in blood and brain using microdialysis and stable labelled isotope].

Jiajun Ling, Xiujun Wu, Xiang Fu

OBJECTIVE: Using the stable isotopes as the internal standard of microdialysis technology to establish a new method to study the whole and local brain dynamics of nicotine percutaneous preparations. METHOD: Using th healthy rats as experimental animals, administrating nicotine in abdominal transdermal …

cn (code pays fourni par la source)