Suja Mohammed

Influence of pretreated coconut shell on gasification product yield

Sobri Muda, Razi Ahmad, Suja Mohammed, W.A.M Wan Ahmad et autres

Gasification of untreated and pretreated coconut shell (CS) was carried out in a fixed-bed reactor to assess the effect of temperature (600, 650, 700, 750, and 800 °C) and holding time (30 and 40 min) on gases composition. The untreated CS was …

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PACAP-PAC1 Receptor Activation Is Necessary for the Sympathetic Response to Acute Intermittent Hypoxia

Melissa M.J. Farnham, Vikram J. Tallapragada, Edward T. O’Connor, Polina E. Nedoboy et autres

Repetitive hypoxia is a key feature of obstructive sleep apnoea (OSA); a condition characterised by intermittent airways obstruction. Patients with OSA present with persistent increases in sympathetic activity and commonly develop hypertension. The objectives of this study were to determine if the …

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Microglia in the RVLM of SHR have reduced P2Y12R and CX3CR1 expression, shorter processes, and lower cell density

E Myfanwy Cohen, Suja Mohammed, Mary M. Kavurma, Polina E. Nedoboy et autres

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Platelet-rich plasma injections: an emerging therapy for chronic discogenic low back pain

Suja Mohammed, James Yu

Autologous platelet-rich plasma (PRP) injections have been investigated in recent years as an emerging therapy for various musculoskeletal conditions, including lumbar degenerative disc disease. Although PRP has received increasing attention from medical science experts, comprehensive clinical reports of its efficacy are limited …

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Microglial number is related to the number of tyrosine hydroxylase neurons in SHR and normotensive rats

Komal Kapoor, Amol Bhandare, Suja Mohammed, Melissa M.J. Farnham et autres

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Dynamic changes in the relationship of microglia to cardiovascular neurons in response to increases and decreases in blood pressure

Komal Kapoor, Amol Bhandare, Polina E. Nedoboy, Suja Mohammed et autres

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pSer40 tyrosine hydroxylase immunohistochemistry identifies the anatomical location of C1 neurons in rat RVLM that are activated by hypotension

Paul M. Pilowsky, Polina E. Nedoboy, Suja Mohammed, Komal Kapoor et autres

Identification of neurons, and their phenotype, that are activated in response to specific stimuli is a critical step in understanding how neural networks integrate inputs to produce specific outputs. Here, we developed novel mouse monoclonal antibodies of different IgG isotypes that are …

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pSer40 tyrosine hydroxylase immunohistochemistry identifies the anatomical location of C1 neurons in rat RVLM that are activated by hypotension

Polina E. Nedoboy, Suja Mohammed, Komal Kapoor, Amol Bhandare et autres

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Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells

Wei Deng, Melissa M.J. Farnham, Ewa M. Goldys, Suja Mohammed et autres

For the first time the efficiency of gene knockdown of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor 1 (PAC1R) is demonstrated by employing gold nanocomplexes. This gene knockdown subsequently affects the action of PACAP on neurite outgrowth in PC12 cells. These nanocomplexes …

Antagonism of PACAP or Microglia Function Worsens the Cardiovascular Consequences of Kainic-Acid-Induced Seizures in Rats

Amol Bhandare, Suja Mohammed, Paul M. Pilowsky, Melissa M.J. Farnham

Seizures are accompanied by cardiovascular changes that are a major cause of sudden unexpected death in epilepsy (SUDEP). Seizures activate inflammatory responses in the cardiovascular nuclei of the medulla oblongata and increase neuronal excitability. Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide …

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A gene encoding a new cold-active lipase from an Antarctic isolate of Penicillium expansum

Suja Mohammed, Junior Te’o, Helena Nevalainen

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A Synthetic biology approach to shed light onto the black box of the brain

Yagiz Alp Aksoy, Suja Mohammed, Paul M. Pilowsky