Andreas Heyland

Microbiome stewardship: definition and guiding principles for implementation

Kieran C. O’Doherty, Mikaela Beijbom, Emma Allen‐Vercoe, Mallory J. Choudoir et autres

Microbiomes are essential for ecosystem, plant, animal, and human health. There is accumulating evidence that changes to microbiomes from anthropogenic activities are associated with adverse health outcomes. Despite this evidence and calls for action, almost no oversight mechanisms exist to protect microbiomes …

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Developmental effects of sulfated thyroid hormones in sea urchin skeletogenesis suggest activation of non-canonical thyroid hormone signaling pathway

Katherine Tieman, Andreas Heyland

Thyroid hormones (THs) are essential regulators of metabolism, homeostasis, and development in metazoans. The canonical genomic pathway involves THs binding to nuclear thyroid hormone receptors (NTHRs), which modulate gene expression in vertebrates. In contrast, non-genomic pathways involve THs interacting with membrane-bound or …

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Thyroid hormones reversibly inhibit metamorphic development in ophiuroid larvae

Elias Taylor, Jonathan D. Allen, Andreas Heyland

The timing of metamorphosis and settlement is critical for the survival and reproductive success of marine animals with biphasic life cycles. Thyroid hormones (THs) regulate developmental timing in diverse groups of chordates, including the regulation of metamorphosis in amphibians, teleosts, lancelets, tunicates …

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Implementation of Dunaliella tertiolecta and Desmodesmus communis in a photobioreactor prototype for treatment of wastewater in a recirculating aquaculture system

Kathleen P. Nolan, Jordan Roszell, Robert Hanner, Andreas Heyland

Inline photobioreactors (PBRs) are a promising tool for nutrient removal from aquacultural wastewater and production of valuable algal biomass, yet few PBR systems have been rigorously tested. Optimization of algal growth screening across species and strains of interest under specific water conditions …

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Stimulating a Canadian narrative for climate

Catherine Potvin, Divya Sharma, Irena F. Creed, Sally N. Aitken et autres

This perspective documents current thinking around climate actions in Canada by synthesizing scholarly proposals made by Sustainable Canada Dialogues (SCD), an informal network of scholars from all 10 provinces, and by reviewing responses from civil society representatives to the scholars’ proposals. Motivated …

Stimulating a Canadian narrative for climate

Catherine Potvin, Divya Sharma, Irena F. Creed, Sally N. Aitken et autres

This perspective documents current thinking around climate actions in Canada by synthesizing scholarly proposals made by Sustainable Canada Dialogues (SCD), an informal network of scholars from all 10 provinces, and by reviewing responses from civil society representatives to the scholars’ proposals. Motivated …

Shared regulatory function of non-genomic thyroid hormone signaling in echinoderm skeletogenesis

Elias Taylor, Megan Corsini, Andreas Heyland

Thyroid hormones are crucial regulators of metamorphosis and development in bilaterians, particularly in chordate deuterostomes. Recent evidence suggests a role for thyroid hormone signaling, principally via 3,5,3',5'-Tetraiodo-L-thyronine (T4), in the regulation of metamorphosis, programmed cell death and skeletogenesis in echinoids (sea urchins …

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DNA at the whim of the water: environmental DNA as a course-based undergraduate research experience

Kathleen P. Nolan, Daniel Z. Grunspan, Erika Myler, Nava Brimble et autres

Course-based undergraduate research experiences (CUREs) increase student access to high impact research experiences. CUREs engage students in the scientific process by learning how to pose scientific questions, develop hypotheses, and generate data to test them. Environmental DNA (eDNA) is a growing field …

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Shared regulatory function of non-genomic thyroid hormone signaling in echinoderm skeletogenesis

Elias Taylor, Andreas Heyland

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Thyroid hormone membrane receptor binding and transcriptional regulation in the sea urchin Strongylocentrotus purpuratus

Elias Taylor, Hannah Wynen, Andreas Heyland

Thyroid hormones (THs) are small amino acid derived signaling molecules with broad physiological and developmental functions in animals. Specifically, their function in metamorphic development, ion regulation, angiogenesis and many others have been studied in detail in mammals and some other vertebrates. Despite …

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Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier

Sima Jonusaite, Nathalie Oulhen, Yasushi Izumi, Mikio Furuse et autres

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Thyroid hormone-induced cell death in sea urchin metamorphic development

Hannah Wynen, Elias Taylor, Andreas Heyland

Thyroid hormones (THs) are important regulators of development, metabolism and homeostasis in metazoans. Specifically, they have been shown to regulate the metamorphic transitions of vertebrates and invertebrates alike. Indirectly developing sea urchin larvae accelerate the formation of juvenile structures in response to …

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