Dong Hyuk Youn

Intratracheal Neomycin Attenuates TBI-induced Secondary Brain Injury via Modulation of Lung Dysbiosis and Inhibition of the NLRP3 Inflammasome

Harry Jung, Dong Hyuk Youn, Hyun‐Jung Kang, Sun-Wha Im et autres

Chinese prescription Kangen-karyu attenuates neuronal damage and improves cognitive function in global cerebral ischemia/reperfusion by regulating ROS-mediated MAPK activation

Ji Hyeon Lee, Jong-Tae Kim, Sung Woo Han, Seongwon Pak et autres

Objective: Global cerebral ischemia is a well-established experimental model for studying hippocampal vulnerability and memory impairment. This study investigated the neuroprotective potential of Kangen-karyu (KK) in a mouse model of global cerebral ischemia/reperfusion injury induced by bilateral common carotid artery occlusion (BCCAO). …

kr, us (code pays fourni par la source)

Therapeutic Effect of Alpha-Pinene on In Vitro and In Vivo Models of Mild Traumatic Brain Injury

Harry Jung, Tae Yeon Kim, Dong Hyuk Youn, Sung Woo Han et autres

We aimed to investigate the therapeutic effects of alpha-pinene (α-pinene), a major component of phytoncide, in in vitro and in vivo models of mild traumatic brain injury (mTBI), raising the possibility of treating mTBI, a condition currently lacking adequate therapies. An in …

kr, us (code pays fourni par la source)

Potential Protective Effects of Naloxone in Traumatic Brain Injury Through JAK2/STAT3 Signaling Modulation

Dong Hyuk Youn, Harry Jung, Jihyeon Lee, Seongwon Pak et autres

Background: We evaluated the potential neuroprotective effects of naloxone in moderate traumatic brain injury (TBI), focusing on its ability to alleviate neuroinflammation, reduce cognitive impairment, and to influence Janus tyrosine kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling markers. …

kr (code pays fourni par la source)

Next‐Generation Respiratory Models: Bridging the Gap Between Biology and Bioengineering

Eun‐Ho Lee, Dong Hyuk Youn, Kang Song, Bumjun Park et autres

The development of in vitro respiratory model systems has advanced physiological understanding and clinical strategies by creating multi-dimensional platforms that replicate in vivo-like microenvironments. These systems bridge the gap between conventional models and human biology, providing insights into respiratory physiology and disease …

kr, us (code pays fourni par la source)

Chinese Prescription Kangen-karyu Attenuates Neuronal Damage and Improves Cognitive Function in Ischemic Stroke by Regulating ROS-Mediated MAPK Activation

Dong Hyuk Youn, Sung Woo Han, Ji Hyeon Lee, Jong-Tae Kim et autres

kr, jp, us, gb (code pays fourni par la source)

Whole-Exome Sequencing Improves Risk Assessments of Adult Moyamoya Disease

Eun Pyo Hong, Eun Jin Ha, Dong Hyuk Youn, Yuwhan Chung et autres

Background and Purpose Whole-exome sequencing (WES) is a valuable tool for identifying causative mutations in adult moyamoya disease (MMD), thereby advancing our understanding of the genetic mechanisms underlying this condition.Here, we conducted the first WESbased association study aimed at identifying genetic modifiers …

us, kr (code pays fourni par la source)

Correction: Identification of stroke biomarkers using proteomic profiling of extracellular vesicles derived from human blood: a preliminary study

Tae Yeon Kim, Jae Yeon Park, Young Min Cho, Dong Hyuk Youn et autres

[This corrects the article DOI: 10.3389/fneur.2025.1587389.].

kr (code pays fourni par la source)

Identification of stroke biomarkers using proteomic profiling of extracellular vesicles derived from human blood: a preliminary study

Tae Yeon Kim, Jae Yeon Park, Young Min Cho, Dong Hyuk Youn et autres

Introduction: Stroke is a devastating brain disease that causes extensive neurological impairment and high mortality. Rapid diagnosis and intervention of stroke are necessary to minimize neurological damage and improve recovery. Extracellular vesicles (EVs) have been identified as potential biomarkers for stroke, suggesting …

kr (code pays fourni par la source)

Advanced hydrogel mesh platform with neural stem cells and human umbilical vein endothelial cells for enhanced axonal regeneration

Jong-Tae Kim, Dong Hyuk Youn, Harry Jung, Eun-Ho Lee et autres

One of the major obstacles to neural recovery following intracerebral hemorrhage (ICH) is the cavity-like lesion that occurs at the site of the hemorrhage, which impedes axonal regeneration. Here, we aim to address this challenge by investigating the migratory mechanisms of neural …

kr (code pays fourni par la source)

One-Step Evaluation of Doxorubicin Toxicity Through Concentration Gradient Generator Integrating Breast Cancer-on-a-Chip

Bum Jun Park, Yujin Song, Dong Hyuk Youn, Sheik Aliya et autres

kr, us (code pays fourni par la source)

Two-Stage Whole-Exome Sequencing Improves to Predict a Risk of Adult Moyamoya Disease in 369,570 Individuals

Eun Pyo Hong, Eun Jin Ha, Dong Hyuk Youn, Yuwhan Chung et autres

kr (code pays fourni par la source)