Lauren E.W. Olsho

Unveiling post-vaccination proteomic signatures in SARS-CoV-2 infection-naïve individuals associated with Omicron breakthrough infections

Yiwen Liu, Eric Lu, Katherine Ellingson, James Hollister et autres

BACKGROUND: Given the persistence of the SARS-CoV-2 virus, it is important to understand the proteome associated with breakthrough infections among COVID-19 vaccinated individuals. METHODS: We conducted a nested case-control study within the frontline worker HEROES-RECOVER cohorts to specify a study population of …

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Intrinsic immunogenicity is a major determinant of type-specific responses in SARS-CoV-2 infections

Grace Quirk, Marta V. Schoenle, Kameron L. Peyton, Jennifer L. Uhrlaub et autres

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COVID-19 Vaccination and Odds of Post–COVID-19 Condition Symptoms in Children Aged 5 to 17 Years

Anna R. Yousaf, Josephine Mak, Lisa Gwynn, Karen Lutrick et autres

Importance: An estimated 1% to 3% of children with SARS-CoV-2 infection will develop post-COVID-19 condition (PCC). Objective: To evaluate the odds of PCC among children with COVID-19 vaccination prior to SARS-CoV-2 infection compared with odds among unvaccinated children. Design, Setting, and Participants: …

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Risk reduction in SARS-CoV-2 infection and reinfection conferred by humoral antibody levels among essential workers during Omicron predominance

James Hollister, Cynthia Porter, Ryan Sprissler, Shawn C. Beitel et autres

The extent to which semi-quantitative antibody levels confer protection against SARS-CoV-2 infection in populations with heterogenous immune histories is unclear. Two nested case-control studies were designed within the multisite HEROES/RECOVER prospective cohort of frontline workers to study the relationship between antibody levels …

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Protection From COVID-19 Vaccination and Prior SARS-CoV-2 Infection Among Children Aged 6 Months–4 Years, United States, September 2022–April 2023

Leora R. Feldstein, Jasmine Ruffin, Ryan E. Wiegand, Lauren Grant et autres

To understand how coronavirus disease 2019 vaccines impact infection risk in children <5 years, we assessed risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection from September 2022 to April 2023 in 3 cohort studies. There was no difference in risk …

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Association of Messenger RNA Coronavirus Disease 2019 (COVID-19) Vaccination and Reductions in Post COVID Conditions Following Severe Acute Respiratory Syndrome Coronavirus 2 Infection in a US Prospective Cohort of Essential Workers

Josephine Mak, Sana Khan, Amadea Britton, Spencer Rose et autres

BACKGROUND: Data are limited on whether vaccination reduces post COVID conditions (PCCs) risk after less severe nonhospitalized coronavirus disease 2019 (COVID-19). This study assessed whether COVID-19 vaccination protected against PCCs in persons with mild initial infections during Delta and Omicron variant predominance. …

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Influenza Vaccine Effectiveness Against Illness and Asymptomatic Infection in 2022–2023: A Prospective Cohort Study

Elizabeth B. White, Lauren Grant, Josephine Mak, Lauren E.W. Olsho et autres

BACKGROUND: Previous estimates of vaccine effectiveness (VE) against asymptomatic influenza virus infection based on seroconversion have varied widely and may be biased. We estimated 2022-2023 influenza VE against illness and asymptomatic infection in a prospective cohort. METHODS: In the HEROES-RECOVER cohort, adults …

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Evaluating Immunologic and Illness Outcomes of SARS-CoV-2 Infection in Vaccinated and Unvaccinated Children Aged ≥ 5 Years, in a Multisite Longitudinal Cohort

Cynthia Porter, Zoë L. Lyski, Jennifer L. Uhrlaub, Katherine Ellingson et autres

Hybrid immunity, as a result of infection and vaccination to SARS-CoV-2, has been well studied in adults but limited evidence is available in children. We evaluated the antibody responses to primary SARS-CoV-2 infection among vaccinated and unvaccinated children aged ≥ 5 years. …

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Mentoring and Communities of Practice in a School Nutrition Manager Training Program

Kelly Patlan, Meaghan E. Glenn, Beth Boulay, Kelly Lack et autres

Risk reduction in SARS-CoV-2 infection and reinfection conferred by humoral antibody levels among essential workers during Omicron predominance

James Hollister, Cynthia Porter, Ryan Sprissler, Shawn C. Beitel et autres

Abstract The extent to which semi-quantitative antibody levels confer protection against SARS-CoV-2 infection in populations with heterogenous immune histories is unclear. Two nested case-control studies were designed within the multisite HEROES/RECOVER prospective cohort of frontline workers to study the relationship between antibody …

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Facilitators & Barriers to Implementing E-STAR, a Team Nutrition School Nutrition Manager Training and Professional Development Program

Meaghan E. Glenn, Kelly Patlan, Beth Boulay, Kelly Lack et autres

Objectives: To investigate facilitators and barriers to school nutrition manager (SNM) engagement in the Team Nutrition Enhanced Strategies, Training, Action Plans, and Resources (E-STAR) program, developed by the United States Department of Agriculture’s Food and Nutrition Service and the Institute of Child …

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Hybrid Immunity and SARS-CoV-2 Antibodies: Results of the HEROES–RECOVER Prospective Cohort Study

James K. Romine, Huashi Li, Melissa M. Coughlin, Jefferson M. Jones et autres

BACKGROUND: There are limited data on whether hybrid immunity differs by count and order of immunity-conferring events (infection with severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] or vaccination against coronavirus disease 2019 [COVID-19]). From a multi-site cohort of frontline workers, we examined …

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