Accès ouvert
2026
article
OpenAlex
Marianna Contrada, Giovanni Morone, Rocco Salvatore Calabrò, Federica Scarfone et autres
BACKGROUND: Pain is a critical yet frequently underestimated component in the care of patients with acquired brain injury (ABI) and disorders of consciousness (DoC). Because these individuals often lack the ability to communicate verbally or purposefully, clinicians face substantial challenges in recognizing …
it
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2026
article
OpenAlex
Lucia Francesca Lucca, Maria Daniela Cortese, Maria Ursino, Francesco Riganello
BACKGROUND: Disorders of consciousness (DoC) remain among the most challenging conditions in neurorehabilitation, with misdiagnosis rates approaching 40% and major implications for treatment planning, prognosis, and ethical decision-making. Current European and American guidelines recommend standardized behavioral assessments and, where available, advanced neuroimaging …
it
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Accès ouvert
2025
article
OpenAlex
Francesco Riganello, Maria Daniela Cortese, Martina Vatrano, Lucia Francesca Lucca et autres
PURPOSE: Paroxysmal sympathetic hyperactivity (PSH) is a severe complication of acquired brain injuries (ABIs), characterized by sudden autonomic surges that exacerbate clinical outcomes. Its pathophysiology remains debated, and early biomarkers are lacking. This study aims to investigate autonomic changes preceding PSH and …
it, us, ca
(code pays fourni par la source)
2025
article
OpenAlex
Marianna Contrada, Ivan Giuseppe Cammarata, Federica Scarfone, Martina Vatrano et autres
BACKGROUND: There has been limited research on the mental health of those caring for individuals with chronic disorders of consciousness (DoCs), particularly in comparing caregivers of patients managed at home versus those admitted to Long-Term Care Specialized Units (LTCSUs). METHODS: This prospective …
it
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Accès ouvert
2025
article
OpenAlex
Francesco Riganello, Maria Daniela Cortese, Martina Vatrano, Lucia Francesca Lucca et autres
Disorders of consciousness (DoC), including unresponsive wakefulness syndrome (UWS/VS) and minimally conscious state (MCS), pose significant diagnostic challenges due to their complexity and high misdiagnosis rates. This study investigates the prognostic potential of heart rate variability (HRV) ratios between stimulation and baseline, …
it, ca
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Accès ouvert
2025
review
OpenAlex
Francesca Giulia Magnani, Filippo Barbadoro, Camilla Ippoliti, Mario Stanziano et autres
Introduction: Consciousness relies on both cortical and subcortical structures and their feedforward and feedback pathways. Within this framework, the thalamus represents a relay station enabling the transmission, reception, and integration of information. However, it is divided into several nuclear groups each composed …
it
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Accès ouvert
2025
article
OpenAlex
Giovanni Nattino, Michele Acler, Stefano Bargellesi, Giannettore Bertagnoni et autres
Background: Severe Acquired Brain Injury (sABI) presents significant challenges in clinical management and rehabilitation due to its diverse and complex nature. The primary objective of the Tiresia project is to identify medium and medium-to-long-term prognostic factors for patients with sABI and to …
it
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Accès ouvert
2024
article
OpenAlex
Marianna Contrada, Federica Scarfone, Maria Girolama Raso, Lucia Francesca Lucca et autres
BACKGROUND/OBJECTIVES: Cranioplasty (CP) is the main surgical procedure aiming to repair a morphological defect in the skull. It has been shown that early CP is useful for patients with traumatic brain injury (TBI) to achieve functional recovery, whereas few studies have investigated …
it
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Accès ouvert
2024
preprint
OpenAlex
Marianna Contrada, Federica Scarfone, Maria Girolama Raso, Lucia Francesca Lucca et autres
Cranioplasty (CP) is the main surgical procedure aimed at reproducing a structural or morphological defect of the skull. It has been shown that cranioplasty can be useful for patients with traumatic brain injury (TBI) to achieve functional cognitive and motor improvements. Here, …
it
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Accès ouvert
2024
article
OpenAlex
Maria Elena Pugliese, Riccardo Battaglia, Maria Ursino, Lucia Francesca Lucca et autres
Venous thromboembolism (VTE) (deep vein thrombosis and its complication, pulmonary embolism) is a major cause of morbidity and mortality in hospitalized patients and about 7% of these cases are due to immobility secondary to a neurological impairment. Acquired brain injury (ABI) has …
it
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Accès ouvert
2024
article
OpenAlex
Francesco Piccione, Antonio Cerasa, Paolo Tonin, Simone Carozzo et autres
BACKGROUND: Foot drop syndrome (FDS), characterized by severe weakness and atrophy of the dorsiflexion muscles of the feet, is commonly found in patients with severe acquired brain injury (ABI). If the syndrome is unilateral, the cause is often a peroneal neuropathy (PN), …
it
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Accès ouvert
2023
article
OpenAlex
Lucia Francesca Lucca, Luisa Spezzano, Francesco Bono, Maria Ursino et autres
Although botulinum toxin is widely considered an effective and safe treatment for a variety of neurological conditions (such as disabling spasticity), local or systemic adverse effects have often been reported. This study describes three cases of patients with severe acquired brain injury …
it
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