Maxwell Y Lee

Impact of Beers Criteria Medications in Elderly Patients With Head and Neck Cancer

Maxwell Y Lee, Mason Sakamoto, Dale Daniel Kim, Andrey Finegersh et autres

BACKGROUND: Head and neck cancer patients often experience polypharmacy due to complex treatments and comorbidities. The Beers Criteria is a list of potentially inappropriate medications (PIMs) for patients above age 65 developed by the American Geriatrics Society. We hypothesize that increased use …

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Single-cell spatial transcriptomics uncovers niches that govern response to PD-1/PD-L1 blockade in cutaneous squamous cell carcinoma

Maxwell Y Lee, Alistaire R Sherman, Luis Martínez Ramírez, Mobeen Rahman et autres

Neoadjuvant PD-1/PD-L1 blockade demonstrates robust efficacy in cutaneous squamous cell carcinoma, yet a significant proportion of patients do not achieve a major pathological response for unclear reasons. Here, we characterize spatially resolved gene expression profiles before, during, and after treatment in cutaneous …

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Single-cell spatial transcriptomics uncovers niches that govern response to PD-1/PD-L1 blockade in cutaneous squamous cell carcinoma

Maxwell Y Lee, Alistaire R Sherman, Luis Martínez Ramírez, Mobeen Rahman et autres

BACKGROUND: Neoadjuvant PD-1/PD-L1 blockade yields robust efficacy in advanced cutaneous squamous cell carcinoma (cSCC), yet many patients fail to achieve a complete or major pathologic response. The reasons why some patients experience response but others do not are unclear. METHODS: We profiled …

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Table S2 from Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer

Navdeep Malik, Young‐Im Kim, Hualong Yan, Yu‐Chou Tseng et autres

This is supplementary Table 2.

Table S1 from Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer

Navdeep Malik, Young‐Im Kim, Hualong Yan, Yu‐Chou Tseng et autres

This is supplementary Table 1.

Figure S1-9 from Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer

Navdeep Malik, Young‐Im Kim, Hualong Yan, Yu‐Chou Tseng et autres

This file contains supplementary figure 1-9.

Table S3 from Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer

Navdeep Malik, Young‐Im Kim, Hualong Yan, Yu‐Chou Tseng et autres

This is supplementary Table 3.

Table S4. from Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer

Navdeep Malik, Young‐Im Kim, Hualong Yan, Yu‐Chou Tseng et autres

This is supplementary Table 4.

Author response for "Organic composition of ultrafine particles formed from automotive braking"

Adam Thomas, Véronique Perraud, Maxwell Y Lee, Berenice Rojas et autres

Effects of diagnostic delays in head and neck cancer patients presenting to the emergency department

Maxwell Y Lee, Jeffrey D. Huynh, Dale Daniel Kim, John B. Sunwoo et autres

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Procedure time‐of‐day effects on postoperative opioid requirements in children

Clinton L. Fuller, Maxwell Y Lee, Kathleen E. Hosek, Ali Hassanpour et autres

PURPOSE: Postoperative analgesic requirements in adults follow circadian rhythm patterns with requirements for opioids and local anesthetics highest in the morning. Procedure time of day may also potentially affect circadian rhythm patterns with surgery at night promoting wakefulness during nighttime hours. This …

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Detection and identification of single ribonucleotide monophosphates using a dual in-plane nanopore sensor made in a thermoplastic via replication

Junseo Choi, Katie Childers, Steven A. Soper, Collin McKinney et autres

We report the generation of ∼8 nm dual in-plane pores fabricated in a thermoplastic via nanoimprint lithography (NIL). These pores were connected in series with nanochannels, one of which served as a flight tube to allow the identification of single molecules based …

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