Ayhan Balkan

Three-Decade Analysis of Inflammatory Bowel Disease in Türkiye: A Multicenter Study (1993-2024)

Muhammed Bahaddin Durak, Yasir Furkan Çağın, Ayhan Balkan, Yusuf Coşkun et autres

Background/Aims: Inflammatory bowel diseases (IBDs) are increasingly prevalent and challenging globally. Data regarding IBD frequency and severity between Europe and Asia are needed. The aim was to investigate the trend of IBD in Türkiye during the last 3 decades. Materials and Methods: …

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P0498 Relationship Of Disease Activation And Treatment With Pulmonary Function Tests And Obstructive Sleep Apnea Syndrome In Ulcerative Colitis Patients

T Metin, Ayhan Balkan, Hüseyin Emek, Murat Şahan

Abstract Background Ulcerative colitis (UC) is a chronic disease with relapses and remissions that may also be associated with extra-intestinal pathologies (1). Patients may develop anemia due to chronic disease or bloody diarrhea, which may cause shortness of breath and limitation in …

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Effect of tarhana soup on serum lipid profile in BALB/c male mice fed a high-fat-diet

Efsane Yavuz, Mustafa Örkmez, Mehmet Akif Bozdayı, Seren Orhan et autres

Aim: With industrialization, there has been an increase in chronic diseases due to continuous change of nutrition. Tarhana is a traditional grain-based product fermented by lactic acid bacteria in Turkish cuisine. This study aims to evaluate possible effects of tarhana on the …

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Direct-acting Antiviral Agents in Patients with Chronic Hepatitis C: Real-life Data

Ayhan Balkan, Yasemin Balkan, Abdullah Emre Yıldırım, Buğra Tolga Konduk et autres

Objectives: In the treatment of chronic hepatitis C (CHC), very high rates of sustained virological response (SVR) have been obtained with direct-acting antivirals.In this study, we aimed to evaluate the efficacy and safety of therapies containing ledipasvir + sofosbuvir (Led + Sof), …

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Plasma lipids, tumor parameters and survival in HCC patients with HBV and HCV

Hikmet Akkız, Brian Irving Carr, Vito Guerra, Rossella Donghia et autres

Data collection: we analyzed prospectively-collected data from our Turkish multi-institutional collaborating HCC working group [30,31], containing information on survival, baseline clinical and tumor characteristics on 1584 HCC patients who had full baseline tumor parameter data, including CT scan information on maximum tumor …

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Serum levels of gamma-glutamyl transpeptidase in relation to HCC human biology and prognosis

Brian Irving Carr, Hikmet Akkız, Bag HG, Ümit Karaoğullarından et autres

BACKGROUND AND AIM: Hepatocellular carcinoma (HCC) biomarkers are limited, as even the best studied, alpha-fetoprotein (AFP), is elevated in no more than 50% of HCC patients. The aim was to evaluate several serum liver function tests in relation to survival and tumor …

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How Aware are We of the Immune Status of Hepatitis B and Hepatitis A in Chronic Hepatitis C Patients? A Multicenter Retrospective Study from Turkey

Nevin İnce, Selma Yegane Tosun, Ayhan Balkan, Mustafa Zafer Uğuz et autres

Kronik HCV enfeksiyonu olan ve hepatit A veya hepatit B virüsü ile süperenfeksiyonu olan hastalar, HCV enfeksiyonu olmayanlara göre daha yüksek morbidite ve mortaliteye sahiptir.Bu çalışmanın amacı, Türkiye'nin farklı bölgelerindeki kronik HCV hastalarında hepatit A ve B seroprevalans oranlarını ve bağışıklığı belirlemektir.Objectives: …

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Real-world efficacy and safety of Ledipasvir + Sofosbuvir and Ombitasvir/Paritaprevir/Ritonavir ± Dasabuvir combination therapies for chronic hepatitis C: A Turkish experience

Bülent Değertekın, Mehmet Demir, Ulus Salih Akarca, Haluk Tarık Kani et autres

BACKGROUND/AIMS: This study aimed to evaluate the real-life efficacy and tolerability of direct-acting antiviral treatments for patients with chronic hepatitis C (CHC) with/without cirrhosis in the Turkish population. MATERIAL AND METHODS: A total of 4,352 patients with CHC from 36 different institutions …

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Erythrocyte Sedimentation Rate and C-Reactive Protein are Markers for Tumor Aggressiveness and Survival in Patients with Hepatocellular Carcinoma

Brian Irving Carr, Hikmet Akkız, Guerra, Rossella Donghia et autres

International audience

Serum levels of inflammatory markers CRP, ESR and albumin in relation to survival for patients with hepatocellular carcinoma

Hikmet Akkız, Brian Irving Carr, Harika Gözükara Bağ, Ümit Karaoğullarından et autres

INTRODUCTION: Hepatocellular carcinoma is associated with several chronic inflammatory conditions. It is increasingly understood that the inflammation may be part of the carcinogenic process and prognostically important. OBJECTIVE: To evaluate the serum levels of three inflammation markers in relation to survival in …

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Optimum design of an air suspension seat using recent structural optimization techniques

Ayhan Balkan, Ali Rıza Yıldız, Sadiq M. Sait, Sujin Bureerat

Abstract This article is on the optimum design of driver seats in commercial vehicles, which are expected to provide high comfort to drivers during long travel distances. This comfort is usually achieved through a pneumatic actuation and suspension motion that provides alignment …

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Treatment of HCV infection with direct-acting antiviral agents. Real life experiences from the Euro-Asian region

Murat Taner Gülşen, Orhan Sezgın, Sevda Aghayeva, Mehmet Demir et autres

BACKGROUND/AIMS: Hepatitis C virus (HCV) infection is a common disease that causes liver cirrhosis, hepatocellular carcinoma, and extra hepatic manifestations with high mortality and morbidity rates. This study aimed to present real-life experiences and results of treatment of HCV infection with direct-acting …

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