Wanglin Duan

Non‐Dynamic Chemical Crosslinking Enables Self‐Healing Hydrogels

Xiaoyu Wu, Bin Zhu, Yurong Chen, Sergio Martín‐Saldaña et autres

ABSTRACT Self‐healing hydrogels possess the intrinsic ability to automatically heal and recover from damage. The healing mechanisms of self‐healing hydrogels are mainly classified into two types: dynamic covalent bonds and non‐covalent bonds. This study reports a series of self‐healing hydrogels based on …

cn, es (code pays fourni par la source)

From passive to bioactive: Engineering a smart Band-Aid for complex wound care

Bin Zhu, Xueling Yang, Haiting Ren, Sergio Martín‐Saldaña et autres

cn, es (code pays fourni par la source)

A Versatile Approach to Synergistically Combine Physical Barriers and Bioactive Agents for Intrauterine Adhesion Prevention

Luyao Feng, Bin Zhu, Zhenni Liu, Rui Jia et autres

Abstract Intrauterine adhesions (IUA) are characterized by fibrotic repair and partial or complete occlusion of the uterine cavity, resulting from endometrial damage. The occurrence of IUA can adversely affect the reproductive and physiological health of women. Developing a delivery platform capable of …

cn, in (code pays fourni par la source)

Succinamide ester-containing adhesive hydrogels with controllable degradation for biomedical applications

Bin Zhu, Yurong Chen, Xueling Yang, Ye Zhu et autres

It is crucial to regulate the degradation rate of adhesive hydrogels for achieving their advanced biomedical applications. Here, a series of succinamide ester-containing adhesive hydrogels were fabricated with controllable degradation through adjusting cyclization degradation behavior. First, the degradation mechanism of succinamide ester-containing …

cn, es (code pays fourni par la source)

Self-Assembling Hydrogels of Naproxen-Conjugated Peptides for Osteoarthritis Treatment

Lulu Yang, Liang Shao, Puhua Hao, Jiaqi Song et autres

: By integrating NSAID pharmacology with self-assembling peptide hydrogel delivery platform, we present a multifunctional strategy that significantly improves upon current OA treatments, underscoring its promise for translational healthcare innovation in OA management.

cn (code pays fourni par la source)

Engineering natural arginine finger to deliver phosphate-containing drugs for treating osteoarthritis

Liang Shao, Lulu Yang, Jiaqi Song, Hongwen Yu et autres

cn (code pays fourni par la source)

Nanozyme‐Engineered Hyaluronic Acid Adhesives Loading Platelet‐Rich Plasma for Multilayered Osteoarthritis Treatment with Pain‐Relief Effect

Yiyang Zhao, Wanglin Duan, Bin Zhu, Yurong Chen et autres

Abstract Osteoarthritis (OA) is the most common degenerative joint disease, causing pain, disability, and economic strain. Combining nanozymes with dopamine (DOPA)‐based adhesives offers a promising approach to effectively modulate the microenvironment of OA‐affected tissues. However, traditional fabrication methods of DOPA‐based adhesives often …

cn, es (code pays fourni par la source)

In Situ Forming Injectable Gelatin‐Based Antibacterial Bioadhesives for Preventing Postoperative Leakage and Abdominal Adhesions

Shibo Hu, Wanglin Duan, Xianzhen Jin, Chaowei Li et autres

Postoperative anastomotic leakage (AL) and abdominal adhesions are two major complications after intestinal surgery, with an incidence of 2-25% for AL and 93% for adhesion. Until now, there is no method addressing AL and abdominal adhesions simultaneously. In this work, Bi-PEG-succinimidyl succinate …

cn (code pays fourni par la source)

Organism-Inspired Antioxidant Bioadhesive with Strong Sealing Ability to Prevent Epidural Adhesion

Yining Gong, Bin Zhu, Yurong Chen, Furong Li et autres

Epidural adhesion or epidural fibrosis is the major reason for postoperative pain, which remains a clinically challenging problem. Current physical barriers fail to provide a satisfactory therapeutic outcome mainly due to their lack of adhesion, inability to prevent fluid leakage, and exhibiting …

cn, es (code pays fourni par la source)

Engineering injectable hyaluronic acid-based adhesive hydrogels with anchored PRP to pattern the micro-environment to accelerate diabetic wound healing

Wanglin Duan, Xianzhen Jin, Yiyang Zhao, Sergio Martín‐Saldaña et autres

cn, es (code pays fourni par la source)

Engineering self-healing adhesive hydrogels with antioxidant properties for intrauterine adhesion prevention

Luyao Feng, Liqun Wang, Yao Ma, Wanglin Duan et autres

Intrauterine adhesion (IUA) is the fibrosis within the uterine cavity. It is the second most common cause of female infertility, significantly affecting women's physical and mental health. Current treatment strategies fail to provide a satisfactory therapeutic outcome for IUA patients, leaving an …

cn, es (code pays fourni par la source)

Succinic Ester‐Based Shape Memory Gelatin Sponge for Noncompressible Hemorrhage without Hindering Tissue Regeneration (Adv. Healthcare Mater. 5/2023)

Ye Zhu, Lining Zhang, Wanglin Duan, Sergio Martín‐Saldaña et autres

Shape Memory Sponges In article 2202122, Xifu Zheng, Yazhong Bu, and co-workers successfully develop a fast degradable shape memory sponge for noncompressible hemorrhage without hindering tissue regeneration. The resulting sponge possesses high mechanical stability and hemostatic efficiency. Meanwhile, its fast degradation, resulting …