Nawazish Naqvi

Correlation of anorectal symptoms and endoanal ultrasound findings after obstetric anal sphincter injuries (OASIS)

Maria Giroux, Nawazish Naqvi, May Alarab

ca (code pays fourni par la source)

405 CORRELATION OF ANORECTAL SYMPTOMS AND ENDOANAL ULTRASOUND FINDINGS AFTER OBSTETRICAL ANAL SPHINCTER INJURIES (OASIS)

Nawazish Naqvi, M Giroux, M Alarab

ca (code pays fourni par la source)

Murradambirra Dhangaang (make food secure): Aboriginal community and stakeholder perspectives on food insecurity in urban and regional Australia

Simone Sherriff, Deanna Kalucy, Allison Tong, Nawazish Naqvi et autres

BACKGROUND: It is widely acknowledged that the invasion by colonial powers of the Australian continent had profound and detrimental impacts on Aboriginal Communities, including food security. Policies of successive governments since European arrival have since further exacerbated the situation, with food insecurity …

au, ca (code pays fourni par la source)

Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts

Amy M. Nicks, Sara Holman, Andrea Y. Chan, Michael Tsang et autres

au, us (code pays fourni par la source)

Remuscularization with triiodothyronine and β1-blocker therapy reverses post-ischemic left ventricular dysfunction and adverse remodeling

Nikolay Bogush, Lin Tan, Emmen Naqvi, John W. Calvert et autres

Abstract Renewal of the myocardium by preexisting cardiomyocytes is a powerful strategy for restoring the architecture and function of hearts injured by myocardial infarction. To advance this strategy, we show that combining two clinically approved drugs, but neither alone, muscularizes the heart …

us, au (code pays fourni par la source)

Abstract 11948: A Standardized Method to Isolate and Purify Cardiomyocytes from Individual Mouse Hearts Irrespective of Postnatal Age

Amy M. Nicks, Sara Holman, Andrea Y. Chan, Ching-ho J Pang et autres

Rational: Primary cardiomyocytes (CMs) are invaluable for understanding postnatal heart development and elucidating disease mechanisms in genetic and pharmacological models, however, a method to obtain freshly purified CMs at any postnatal age, without the need for different age-dependent isolation procedures and cell …

au, us, cn, ru (code pays fourni par la source)

Mechanism-Based Cardiac Regeneration Strategies in Mammals

Nawazish Naqvi, Siiri E. Iismaa, Robert M. Graham, Ahsan Husain

Heart failure in adults is a leading cause of morbidity and mortality worldwide. It can arise from a variety of diseases, with most resulting in a loss of cardiomyocytes that cannot be replaced due to their inability to replicate, as well as …

us, au (code pays fourni par la source)

Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts

Amy M. Nicks, Sara Holman, Andrea Y. Chan, Michael Tsang et autres

Abstract Primary cardiomyocytes are invaluable for understanding postnatal heart development. However, a universal method to obtain freshly purified cardiomyocytes without using different agedependent isolation procedures and cell culture, is lacking. Here, we report the development of a standardised method that allows rapid …

au, us (code pays fourni par la source)

(Murradambirra Dhangaang - Make Food Secure) Aboriginal Community and Stakeholder Perspectives on Food Insecurity in Urban and Regional Australia: A Qualitative Study

Simone Sherriff, Deanna Kalucy, Allison Tong, Nawazish Naqvi et autres

Abstract Background: Food insecurity affects one in five Aboriginal and Torres Strait Islander people residing in non-remote environments. Inequalities in diet contribute to the differential impact on diet-sensitive chronic diseases and the related burden of disease among Aboriginal and Torres Strait Islander …

au, ca (code pays fourni par la source)

Thyroid hormone plus dual-specificity phosphatase-5 siRNA increases the number of cardiac muscle cells and improves left ventricular contractile function in chronic doxorubicin-injured hearts

Lin Tan, Nikolay Bogush, Emmen Naqvi, John W. Calvert et autres

-jetPEI system for delivery of siRNA is already in use in humans, as is T3. Given these considerations, our findings provide a potentially highly translatable strategy for addressing doxorubicin cardiomyopathy, a currently untreatable condition.

us, au (code pays fourni par la source)

DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling

Nikolay Bogush, Lin Tan, Hussain Naib, Ebrahim Faizullabhoy et autres

Cardiomyocytes of newborn mice proliferate after injury or exposure to growth factors. However, these responses are diminished after postnatal day-6 (P6), representing a barrier to building new cardiac muscle in adults. We have previously shown that exogenous thyroid hormone (T3) stimulates cardiomyocyte …

us, au (code pays fourni par la source)

Pressure overload by suprarenal aortic constriction in mice leads to left ventricular hypertrophy without c-Kit expression in cardiomyocytes

Amy M. Nicks, Scott Kesteven, Ming Li, Jianxin Wu et autres

Animal models of pressure overload are valuable for understanding hypertensive heart disease. We characterised a surgical model of pressure overload-induced hypertrophy in C57BL/6J mice produced by suprarenal aortic constriction (SAC). Compared to sham controls, at one week post-SAC systolic blood pressure was …

au, cn, us (code pays fourni par la source)